Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   KJA80_RS04570 Genome accession   NZ_OD940422
Coordinates   978213..979535 (+) Length   440 a.a.
NCBI ID   WP_002385251.1    Uniprot ID   -
Organism   Enterococcus faecalis isolate WE0851     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 973213..984535
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KJA80_RS04565 (WE0851_00932) rlmH 977357..977836 (-) 480 WP_002355021.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  KJA80_RS04570 (WE0851_00933) htrA 978213..979535 (+) 1323 WP_002385251.1 trypsin-like peptidase domain-containing protein Regulator
  KJA80_RS04575 (WE0851_00934) - 979582..980202 (-) 621 WP_010712879.1 YtpR family tRNA-binding protein -
  KJA80_RS04580 (WE0851_00935) - 980413..980868 (-) 456 WP_002385249.1 universal stress protein -
  KJA80_RS04585 (WE0851_00936) - 981016..981330 (-) 315 WP_002375619.1 thioredoxin family protein -
  KJA80_RS04590 (WE0851_00937) pepA 981342..982418 (-) 1077 WP_002355013.1 glutamyl aminopeptidase -
  KJA80_RS04595 (WE0851_00938) - 982725..983066 (+) 342 WP_002399791.1 PepSY domain-containing protein -

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 45751.06 Da        Isoelectric Point: 5.1212

>NTDB_id=1150606 KJA80_RS04570 WP_002385251.1 978213..979535(+) (htrA) [Enterococcus faecalis isolate WE0851]
MHLLGGYFMQRKDVTPNSDKKSLLQKFGIGLAGGLLGGALILGGAYSGIIPTPNGGNNAATTTSTNHGDTKVSNVSYNVS
SDVTKAVKKVQNSVVSVINMQSASNNSSADDPFGGLFGGNEGTQDSSGNNGNDLEAASEGSGVIYKKDGKTAYVVTNNHV
VDKAQGLEVVLSDGTKVKGELVGTDAYTDLAVIKISSDKVDQVAEFGNSSKITVGEPAIAIGSPLGSDYANSVTQGIISS
VNRNITNKNESGETININAIQTDAAINPGNSGGPLINIEGQVIGINSVKIVQSTSQVSVEGMGFAIPSNDVVNIINQLEK
DGKVTRPALGITMSDLTGISSQQQEQILKIPASVKTGVVVRGVEAATPAEKAGLEKYDVITKVDGQDVSSTTDLQSALYK
KKVGDKMEVTYYRGSKEMKATIDLTIDKSALTQQNNRSNQ

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=1150606 KJA80_RS04570 WP_002385251.1 978213..979535(+) (htrA) [Enterococcus faecalis isolate WE0851]
ATGCACTTATTGGGAGGTTATTTTATGCAACGAAAAGATGTTACACCTAATTCAGATAAAAAAAGTTTATTGCAAAAATT
TGGGATTGGTTTAGCTGGCGGCTTACTTGGTGGTGCCCTTATTCTAGGAGGCGCTTATTCTGGGATTATTCCCACACCCA
ACGGCGGAAATAATGCGGCGACGACGACGTCCACTAACCACGGCGACACAAAAGTCAGCAATGTGAGTTACAATGTTTCT
AGCGATGTCACAAAAGCCGTGAAAAAAGTTCAAAATTCTGTGGTTTCTGTCATTAATATGCAAAGTGCTAGCAACAATTC
TTCGGCAGATGATCCTTTTGGGGGATTGTTCGGTGGGAATGAAGGTACGCAAGACTCTTCCGGCAACAATGGTAACGATT
TAGAAGCAGCCAGTGAAGGTAGTGGGGTTATTTATAAGAAAGATGGTAAAACGGCTTATGTCGTGACAAATAACCACGTC
GTAGATAAAGCGCAAGGATTGGAAGTTGTTTTGTCTGATGGTACCAAAGTGAAAGGCGAATTAGTCGGAACCGATGCTTA
CACGGATTTAGCCGTGATTAAAATTTCTTCCGACAAAGTTGATCAAGTCGCTGAGTTTGGGAATTCTAGTAAAATCACAG
TCGGTGAGCCTGCTATTGCAATTGGTTCCCCGCTAGGTTCTGATTATGCTAACTCTGTCACACAAGGAATCATCTCTTCT
GTGAATAGAAATATTACCAATAAAAACGAGTCTGGTGAAACCATCAATATTAATGCCATTCAAACCGATGCTGCTATTAA
TCCAGGAAACTCTGGTGGTCCACTAATCAATATTGAAGGACAAGTCATTGGAATTAACTCAGTAAAAATTGTGCAATCAA
CTAGTCAAGTGAGCGTTGAAGGGATGGGCTTTGCCATTCCAAGTAATGACGTAGTCAACATTATCAACCAATTAGAAAAA
GATGGTAAAGTGACGCGGCCAGCTCTAGGGATTACGATGTCTGATTTAACAGGTATCTCTTCACAACAACAAGAACAAAT
TTTAAAAATTCCAGCTTCTGTAAAAACTGGCGTAGTGGTTCGTGGTGTTGAAGCAGCGACCCCTGCTGAAAAGGCTGGAT
TGGAAAAATACGATGTTATCACGAAAGTTGACGGCCAAGACGTAAGCTCTACTACAGATTTACAAAGCGCGCTTTATAAG
AAAAAAGTTGGCGACAAAATGGAAGTGACTTATTATCGTGGTTCTAAAGAAATGAAAGCAACCATCGATTTAACCATTGA
TAAGTCAGCTTTAACACAACAAAATAATCGCAGCAATCAATAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(140-285)

Peptidase family M50 (Peptidase_M50)

(5-424)

PDZ domain (PDZ_2)

(327-424)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

53.171

93.182

0.495
  htrA Streptococcus mutans UA159

58.63

82.955

0.486
  htrA Streptococcus mitis NCTC 12261

55.135

84.091

0.464
  htrA Streptococcus pneumoniae TIGR4

55.807

80.227

0.448
  htrA Streptococcus pneumoniae Rx1

55.807

80.227

0.448
  htrA Streptococcus pneumoniae D39

55.807

80.227

0.448
  htrA Streptococcus pneumoniae R6

55.807

80.227

0.448

Multiple sequence alignment