Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   DQL00_RS07840 Genome accession   NZ_LS483523
Coordinates   1452738..1453442 (+) Length   234 a.a.
NCBI ID   WP_000722076.1    Uniprot ID   Q9S1K0
Organism   Streptococcus pneumoniae strain 4041STDY6836169     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1447738..1458442
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL00_RS07820 coaC 1448028..1448579 (-) 552 WP_001284124.1 phosphopantothenoylcysteine decarboxylase -
  DQL00_RS07825 coaB 1448591..1449280 (-) 690 WP_000699499.1 phosphopantothenate--cysteine ligase -
  DQL00_RS07830 - 1449510..1451180 (+) 1671 WP_000845279.1 formate--tetrahydrofolate ligase -
  DQL00_RS12250 - 1451286..1451411 (-) 126 WP_001818232.1 hypothetical protein -
  DQL00_RS07835 mutY 1451508..1452683 (+) 1176 WP_023396302.1 A/G-specific adenine glycosylase -
  DQL00_RS07840 micA 1452738..1453442 (+) 705 WP_000722076.1 response regulator YycF Regulator
  DQL00_RS07845 micB 1453435..1454784 (+) 1350 WP_000886213.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQL00_RS07850 vicX 1454786..1455595 (+) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  DQL00_RS07855 relB 1455686..1455928 (+) 243 WP_000208079.1 type II toxin-antitoxin system RelB family antitoxin -
  DQL00_RS07860 - 1455930..1456184 (+) 255 WP_023396301.1 type II toxin-antitoxin system RelE family toxin -
  DQL00_RS07865 - 1456231..1457007 (+) 777 WP_023396300.1 potassium channel family protein -
  DQL00_RS07870 - 1457263..1458249 (-) 987 WP_000204727.1 L-lactate dehydrogenase -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26815.63 Da        Isoelectric Point: 4.7164

>NTDB_id=1142978 DQL00_RS07840 WP_000722076.1 1452738..1453442(+) (micA) [Streptococcus pneumoniae strain 4041STDY6836169]
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMRNNA

Nucleotide


Download         Length: 705 bp        

>NTDB_id=1142978 DQL00_RS07840 WP_000722076.1 1452738..1453442(+) (micA) [Streptococcus pneumoniae strain 4041STDY6836169]
ATGAAAAAAATACTAATTGTAGATGATGAGAAACCAATCTCGGATATTATCAAGTTTAATATGACCAAGGAAGGTTACGA
GGTTGTAACTGCTTTTAATGGTCGTGAAGCGCTAGAGCAATTTGAAGCAGAGCAACCAGATATTATTATTCTGGATTTGA
TGCTTCCAGAAATTGATGGTTTAGAAGTTGCTAAGACCATTCGTAAGACAAGCAGTGTGCCCATTCTTATGCTTTCAGCC
AAAGATAGTGAATTTGATAAGGTTATCGGTTTGGAACTTGGGGCAGATGACTATGTAACGAAACCCTTCTCCAATCGTGA
GTTGCAGGCGCGTGTTAAAGCTCTTCTGCGTCGTTCTCAACCTATGCCAGTAGATGGGCAGGAAGCAGATAGTAAACCTC
AACCTATCCAAATTGGGGATTTAGAAATTGTTCCAGACGCCTACGTGGCTAAAAAATATGGCGAAGAACTAGACTTAACC
CATCGTGAATTTGAGCTTTTGTATCATTTAGCATCGCATACAGGTCAAGTCATCACGCGCGAACACTTGCTTGAGACTGT
CTGGGGTTATGACTATTTTGGTGATGTCCGTACAGTTGATGTGACTGTACGACGTCTGCGTGAGAAGATTGAAGATACGC
CCAGCCGACCAGAGTATATCTTGACGCGCCGTGGTGTAGGGTATTACATGAGAAATAATGCTTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 1NXS
  PDB 2A9O
  PDB 2A9P

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

100

100

1
  vicR Streptococcus mutans UA159

78.541

99.573

0.782
  covR Streptococcus salivarius strain HSISS4

44.156

98.718

0.436
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.478

98.291

0.427
  scnR Streptococcus mutans UA159

38.197

99.573

0.38

Multiple sequence alignment