Detailed information NTG1142837

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQL26_RS04665
• Genome accession: NZ_LS483521
• Coordinates: 909757..910593 (+)
• Length: 278 a.a.
• NCBI ID: WP_111693218.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC8316
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 904757..915593

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL26_RS04635 (NCTC8316_00925)	-	905246..905680 (+)	435	WP_111693216.1	hypothetical protein	-
DQL26_RS04640 (NCTC8316_00926)	-	905730..906641 (-)	912	WP_047235287.1	diacylglycerol/lipid kinase family protein	-
DQL26_RS04645 (NCTC8316_00927)	trhA	906758..907408 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DQL26_RS04650 (NCTC8316_00928)	-	907405..907845 (-)	441	WP_011017769.1	DUF1836 domain-containing protein	-
DQL26_RS04655 (NCTC8316_00929)	ylqF	908064..908912 (+)	849	WP_038433405.1	ribosome biogenesis GTPase YlqF	-
DQL26_RS04660 (NCTC8316_00930)	-	908902..909693 (+)	792	WP_111693217.1	ribonuclease HII	-
DQL26_RS04665 (NCTC8316_00931)	dprA	909757..910593 (+)	837	WP_111693218.1	DNA-processing protein DprA	Machinery gene
DQL26_RS04670 (NCTC8316_00932)	topA	910700..912829 (+)	2130	WP_111693219.1	type I DNA topoisomerase	-
DQL26_RS04675 (NCTC8316_00933)	-	912904..913710 (-)	807	Protein_856	LysR family transcriptional regulator	-
DQL26_RS04685 (NCTC8316_00934)	-	913723..914280 (+)	558	Protein_857	PTS sugar transporter subunit IIC	-
DQL26_RS04690 (NCTC8316_00935)	-	914295..915287 (+)	993	WP_021340798.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31073.07 Da
• Isoelectric Point: 9.2565

>NTDB_id=1142837 DQL26_RS04665 WP_111693218.1 909757..910593(+) (dprA) [Streptococcus pyogenes strain NCTC8316]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1142837 DQL26_RS04665 WP_111693218.1 909757..910593(+) (dprA) [Streptococcus pyogenes strain NCTC8316]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAAGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	56.835	100	0.568
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367