Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DQL19_RS03815 Genome accession   NZ_LS483480
Coordinates   734877..736094 (+) Length   405 a.a.
NCBI ID   WP_077643717.1    Uniprot ID   -
Organism   Haemophilus influenzae strain NCTC13377     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 729877..741094
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL19_RS03795 (NCTC13377_00747) corC 730842..731741 (-) 900 WP_005648977.1 CNNM family magnesium/cobalt transport protein CorC -
  DQL19_RS03800 (NCTC13377_00748) ampD 732365..732925 (-) 561 WP_014550480.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  DQL19_RS03805 (NCTC13377_00749) pilA 733040..733489 (+) 450 WP_077643715.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  DQL19_RS03810 (NCTC13377_00750) pilB 733486..734880 (+) 1395 WP_077643716.1 GspE/PulE family protein Machinery gene
  DQL19_RS03815 (NCTC13377_00751) pilC 734877..736094 (+) 1218 WP_077643717.1 type II secretion system F family protein Machinery gene
  DQL19_RS03820 (NCTC13377_00752) pilD 736091..736783 (+) 693 WP_041175037.1 A24 family peptidase Machinery gene
  DQL19_RS03825 (NCTC13377_00753) rho 736839..738101 (-) 1263 WP_015701557.1 transcription termination factor Rho -
  DQL19_RS03830 (NCTC13377_00754) metJ 738349..738666 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  DQL19_RS03835 (NCTC13377_00755) cueR 738680..739066 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  DQL19_RS03840 (NCTC13377_00756) - 739143..739349 (+) 207 WP_005686717.1 heavy-metal-associated domain-containing protein -
  DQL19_RS03845 (NCTC13377_00757) - 739435..739641 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DQL19_RS03850 (NCTC13377_00758) - 739715..739921 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DQL19_RS03855 (NCTC13377_00759) - 739995..740201 (+) 207 WP_015701556.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 46052.18 Da        Isoelectric Point: 9.6104

>NTDB_id=1142493 DQL19_RS03815 WP_077643717.1 734877..736094(+) (pilC) [Haemophilus influenzae strain NCTC13377]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISHGLTHIKLQQNWQFGAKTKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGIPLNQALDSFLPRTQTWQTKTLVNDIILDKEVRSILQWVSQGY
AFSDSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFNM
GSVIQ

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=1142493 DQL19_RS03815 WP_077643717.1 734877..736094(+) (pilC) [Haemophilus influenzae strain NCTC13377]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAGTTAATAAGCCACGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAAA
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGCAATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAACGAATGGCTTGAACGGCTGCTTCAATCTATTGAATCTGGCTT
AGCATTCTCACAAGCTATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTTGTTTGTAAAAAAATAGCCACACATCGTAGCCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTAGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCCGAATTACCAACAATAACCGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTCTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAGGCTGGCATTCCGCTTAATCAAGCGCTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAACCAAGACGCTTGTAAATGACATCATATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGCTAT
GCGTTTTCTGATAGTGTAAGTAGCGATCTTTTTCCGATGGAAGCACAACAAATGTTACAAATTGGCGAGCAAAGCGGAAA
ACTCGCTTTGATGCTGGAGCATATTGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAATGC
TAGAACCATTAATGATGGTGATCATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAATATG
GGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)

Type II secretion system (T2SS), protein F (T2SSF)

(266-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.044

100

0.973
  pilC Haemophilus influenzae Rd KW20

96.798

100

0.97
  pilC Glaesserella parasuis strain SC1401

38.75

98.765

0.383

Multiple sequence alignment