Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   DQL19_RS03820 Genome accession   NZ_LS483480
Coordinates   736091..736783 (+) Length   230 a.a.
NCBI ID   WP_041175037.1    Uniprot ID   -
Organism   Haemophilus influenzae strain NCTC13377     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 731091..741783
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL19_RS03800 (NCTC13377_00748) ampD 732365..732925 (-) 561 WP_014550480.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  DQL19_RS03805 (NCTC13377_00749) pilA 733040..733489 (+) 450 WP_077643715.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  DQL19_RS03810 (NCTC13377_00750) pilB 733486..734880 (+) 1395 WP_077643716.1 GspE/PulE family protein Machinery gene
  DQL19_RS03815 (NCTC13377_00751) pilC 734877..736094 (+) 1218 WP_077643717.1 type II secretion system F family protein Machinery gene
  DQL19_RS03820 (NCTC13377_00752) pilD 736091..736783 (+) 693 WP_041175037.1 A24 family peptidase Machinery gene
  DQL19_RS03825 (NCTC13377_00753) rho 736839..738101 (-) 1263 WP_015701557.1 transcription termination factor Rho -
  DQL19_RS03830 (NCTC13377_00754) metJ 738349..738666 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  DQL19_RS03835 (NCTC13377_00755) cueR 738680..739066 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  DQL19_RS03840 (NCTC13377_00756) - 739143..739349 (+) 207 WP_005686717.1 heavy-metal-associated domain-containing protein -
  DQL19_RS03845 (NCTC13377_00757) - 739435..739641 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DQL19_RS03850 (NCTC13377_00758) - 739715..739921 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DQL19_RS03855 (NCTC13377_00759) - 739995..740201 (+) 207 WP_015701556.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26774.79 Da        Isoelectric Point: 9.0938

>NTDB_id=1142494 DQL19_RS03820 WP_041175037.1 736091..736783(+) (pilD) [Haemophilus influenzae strain NCTC13377]
MIYFTMFLLGGILGIALWFYLSGFITRLQQEIYATYIELFPQNRSPFQPHFASIQQKKCGHILRYFLSVGVGFIFLQIAF
KDSIFTVWLGATLLILWAISYLDWHYQLISTTLCLWLLTIGLFGADNNFSLLTLSESIKSAASFFIVFYAIYWIAKFYYG
KEAFGRGDYWLAMALGSFIHLETLPHFLLLASVLGICFSLIHKKKKEFIPFAPFMNLSAVIIYFVKYYWY

Nucleotide


Download         Length: 693 bp        

>NTDB_id=1142494 DQL19_RS03820 WP_041175037.1 736091..736783(+) (pilD) [Haemophilus influenzae strain NCTC13377]
ATGATTTACTTCACAATGTTTTTATTAGGCGGCATCTTAGGGATCGCATTGTGGTTCTACCTATCTGGTTTTATTACCCG
TTTACAGCAAGAGATTTATGCGACTTATATTGAATTATTTCCACAAAACCGTTCTCCATTTCAACCGCACTTTGCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGGTATTTTTTAAGTGTTGGGGTAGGATTTATATTTTTACAAATTGCCTTC
AAAGATTCTATTTTTACTGTATGGCTAGGAGCCACACTTCTTATCCTTTGGGCAATTAGTTATCTTGATTGGCACTATCA
ACTTATTTCTACTACTCTCTGTTTATGGCTACTTACAATCGGTTTATTTGGAGCAGACAATAATTTTTCATTGCTTACGT
TATCTGAAAGCATAAAAAGTGCGGCAAGTTTTTTTATTGTTTTCTACGCAATCTATTGGATTGCAAAATTCTATTACGGA
AAAGAAGCCTTTGGACGGGGAGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCATTTAGAAACCTTACCGCACTT
TTTATTATTAGCCTCAGTTCTTGGAATATGTTTTTCGCTTATTCATAAAAAGAAAAAAGAATTTATACCTTTTGCCCCTT
TTATGAACTTATCAGCTGTCATAATTTATTTCGTCAAATATTACTGGTATTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(93-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae Rd KW20

93.043

100

0.93
  pilD Haemophilus influenzae 86-028NP

93.043

100

0.93

Multiple sequence alignment