Detailed information NTG1142352

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: DQN71_RS11545
• Genome accession: NZ_LS483471
• Coordinates: 2173870..2175048 (+)
• Length: 392 a.a.
• NCBI ID: WP_015606090.1
• Uniprot ID: -
• Organism: Streptococcus cristatus strain NCTC13807
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2168870..2180048

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN71_RS11505 (NCTC13807_02188)	sdaAB	2169641..2170312 (-)	672	WP_015606087.1	L-serine ammonia-lyase, iron-sulfur-dependent subunit beta	-
DQN71_RS11520 (NCTC13807_02191)	comE/comE2	2170657..2171400 (-)	744	WP_005591384.1	competence system response regulator transcription factor ComE	Regulator
DQN71_RS11525 (NCTC13807_02192)	comD/comD1	2171397..2172740 (-)	1344	WP_172456456.1	GHKL domain-containing protein	Regulator
DQN71_RS11530 (NCTC13807_02193)	comC	2172766..2172894 (-)	129	WP_041826850.1	competence protein	Regulator
DQN71_RS11540 (NCTC13807_02195)	rlmH	2173188..2173667 (-)	480	WP_015606089.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
DQN71_RS11545 (NCTC13807_02196)	htrA	2173870..2175048 (+)	1179	WP_015606090.1	S1C family serine protease	Regulator
DQN71_RS11550 (NCTC13807_02197)	spo0J	2175111..2175872 (+)	762	WP_015606091.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 392 a.a.
• Molecular weight: 41335.44 Da
• Isoelectric Point: 5.4758

>NTDB_id=1142352 DQN71_RS11545 WP_015606090.1 2173870..2175048(+) (htrA) [Streptococcus cristatus strain NCTC13807]
MKNASNFFKKSLLLFIVLVVGFIGGSLGNLATAFLNNKMANIGPSSSKTTVSTSYKNTTDTTKAVKKVQNAVVSVITYTG
SNQEGVINNESTSDPQVASEGSGVIYKKEGKYAYLVTNTHVLNGATNPDILLADGSKVPGEVVGSDVYSDISVVRINSEK
VKDVAEFGDSNSLTVGETAIAIGSPLGTEYANSVTQGIISSLGRNVTLQSEDGQNISTTALQTDAAINPGNSGGPLINIQ
GQVIGITSSKISHNGQTAVEGMGFAIPSNDVVNIIKQLEKTGTVTRPALGIQMLDLSNIATSDLSKLRLPSSVKSGILVR
SVQEGMPAENKLQKYDVITKVDDKDVESTSDLQSALYRHSLGDELKVTYFRDGKEATTTIKLTKSTQDLSDN

Nucleotide

• Length: 1179 bp

>NTDB_id=1142352 DQN71_RS11545 WP_015606090.1 2173870..2175048(+) (htrA) [Streptococcus cristatus strain NCTC13807]
ATGAAAAACGCTTCAAATTTCTTTAAAAAATCTTTGTTGCTTTTTATTGTTTTAGTTGTAGGATTTATTGGCGGAAGCCT
AGGAAATTTAGCCACTGCATTTCTTAATAATAAAATGGCTAATATTGGTCCTTCTAGCTCAAAGACCACTGTATCAACGT
CTTATAAAAACACAACCGACACCACAAAGGCTGTAAAAAAGGTTCAAAATGCAGTTGTATCAGTAATTACTTATACAGGT
TCAAATCAAGAAGGAGTGATCAATAATGAATCAACCAGTGATCCTCAAGTAGCTAGTGAGGGATCTGGTGTTATTTATAA
GAAGGAAGGAAAATATGCCTACCTTGTTACCAATACTCACGTGCTAAATGGAGCAACAAATCCTGATATTCTACTAGCAG
ATGGTAGTAAGGTTCCTGGTGAGGTCGTTGGTTCAGATGTTTATTCTGATATTTCTGTAGTAAGAATTAACTCTGAAAAG
GTGAAAGATGTAGCTGAATTTGGAGATTCCAACTCCCTGACAGTAGGAGAAACTGCTATTGCCATCGGAAGCCCTCTCGG
AACAGAATACGCTAACTCTGTTACACAAGGAATCATCTCTAGTTTAGGCAGAAATGTAACTCTCCAATCTGAAGACGGCC
AAAATATTTCCACAACTGCCTTGCAAACAGATGCTGCTATCAACCCTGGTAACTCTGGCGGTCCACTCATCAATATCCAA
GGACAAGTTATCGGTATTACGTCCAGCAAAATCTCTCACAATGGTCAAACTGCTGTAGAAGGCATGGGCTTTGCAATTCC
ATCAAACGATGTTGTCAATATTATCAAGCAATTAGAGAAAACTGGAACAGTAACTCGTCCTGCTCTGGGTATCCAAATGC
TCGATTTATCTAATATCGCCACTTCTGACTTATCAAAATTACGTCTGCCTTCATCTGTAAAATCAGGTATCCTTGTCCGC
TCTGTGCAAGAAGGAATGCCTGCTGAAAATAAACTTCAGAAATACGATGTCATCACAAAAGTTGACGATAAGGATGTTGA
GTCAACCAGTGATTTACAATCTGCTCTCTACAGACACTCTCTGGGAGATGAGTTGAAAGTGACTTACTTTAGGGATGGTA
AAGAAGCTACTACAACCATTAAATTGACCAAATCAACCCAGGACTTAAGTGACAACTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (287-382)

• Peptidase family M50 (Peptidase_M50) (233-386)

• Trypsin-like peptidase domain (Trypsin_2) (101-246)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus gordonii str. Challis substr. CH1	67.595	100	0.681
htrA	Streptococcus pneumoniae Rx1	63.939	99.745	0.638
htrA	Streptococcus pneumoniae D39	63.939	99.745	0.638
htrA	Streptococcus pneumoniae R6	63.939	99.745	0.638
htrA	Streptococcus pneumoniae TIGR4	63.939	99.745	0.638
htrA	Streptococcus mitis NCTC 12261	63.939	99.745	0.638
htrA	Streptococcus mutans UA159	54.342	100	0.559