Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   DQN71_RS11525 Genome accession   NZ_LS483471
Coordinates   2171397..2172740 (-) Length   447 a.a.
NCBI ID   WP_172456456.1    Uniprot ID   -
Organism   Streptococcus cristatus strain NCTC13807     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 2166397..2177740
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN71_RS11490 (NCTC13807_02185) - 2167065..2167859 (+) 795 WP_015606084.1 energy-coupling factor transporter transmembrane component T family protein -
  DQN71_RS11495 (NCTC13807_02186) - 2168046..2168702 (+) 657 WP_015606085.1 LysM peptidoglycan-binding domain-containing protein -
  DQN71_RS11500 (NCTC13807_02187) sdaAA 2168760..2169632 (-) 873 WP_015606086.1 L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha -
  DQN71_RS11505 (NCTC13807_02188) sdaAB 2169641..2170312 (-) 672 WP_015606087.1 L-serine ammonia-lyase, iron-sulfur-dependent subunit beta -
  DQN71_RS11520 (NCTC13807_02191) comE/comE2 2170657..2171400 (-) 744 WP_005591384.1 competence system response regulator transcription factor ComE Regulator
  DQN71_RS11525 (NCTC13807_02192) comD/comD1 2171397..2172740 (-) 1344 WP_172456456.1 GHKL domain-containing protein Regulator
  DQN71_RS11530 (NCTC13807_02193) comC 2172766..2172894 (-) 129 WP_041826850.1 competence protein Regulator
  DQN71_RS11540 (NCTC13807_02195) rlmH 2173188..2173667 (-) 480 WP_015606089.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  DQN71_RS11545 (NCTC13807_02196) htrA 2173870..2175048 (+) 1179 WP_015606090.1 S1C family serine protease Regulator
  DQN71_RS11550 (NCTC13807_02197) spo0J 2175111..2175872 (+) 762 WP_015606091.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 447 a.a.        Molecular weight: 53083.12 Da        Isoelectric Point: 5.5650

>NTDB_id=1142350 DQN71_RS11525 WP_172456456.1 2171397..2172740(-) (comD/comD1) [Streptococcus cristatus strain NCTC13807]
MFELFFWILQAAIEVYFTIVIYEKINKVKSSFYFTFLCAIVLILLPLLILNLESIFSLSRHVLYFLLLLIYPLFFYRYFY
KKEKLSALFSIFLSLLLYLTVQAPTTFFSVIISSITGDSFVNDNWAVFYIMINSISVLLMLKFIDYLPFSIRDFKEEVFK
KTIKRINIFYVIDIFILNISHWLSEDEHFNSFSSMLATICFLIFMTTLFYLKAIREKYEKEEEIRQRELEQLQLQQYTDE
IVSLYNEIRGFRHDYAGMLTSFQTAINTQDIKEIEKIYQEVLVDANLKLRSDKYTYFDLNNVGDSALRSVMTETLFKARE
HQIDLTFEVKEPVETLPIKLLDVVRMASILLNNAVEGAIESYEKMIHVTLVQLDTEIIFVVKNSRKQRKLDLEEIYKPEF
STKGYRRGLGLNNLKEILENYEYIMLDTEISKYDFTQVLTIKRRNSL

Nucleotide


Download         Length: 1344 bp        

>NTDB_id=1142350 DQN71_RS11525 WP_172456456.1 2171397..2172740(-) (comD/comD1) [Streptococcus cristatus strain NCTC13807]
ATGTTTGAATTATTTTTTTGGATATTACAAGCTGCCATTGAAGTATATTTCACTATTGTCATATATGAAAAGATCAATAA
AGTAAAATCGAGTTTTTACTTTACTTTTCTGTGTGCTATAGTCTTAATTTTATTACCCTTACTCATATTAAATTTAGAAT
CTATATTTTCTTTGTCAAGGCATGTTCTATATTTTCTTTTACTACTGATTTATCCTCTTTTTTTCTACAGGTATTTTTAT
AAAAAAGAAAAGTTATCAGCTCTTTTCTCTATATTTCTATCTCTTCTTCTTTATTTAACAGTTCAGGCTCCTACTACATT
TTTTTCCGTCATTATTTCCTCAATTACAGGGGATTCATTTGTAAACGATAATTGGGCTGTCTTTTATATCATGATAAATA
GTATCTCTGTTTTATTAATGCTTAAGTTTATTGATTACTTACCATTTTCTATAAGAGATTTTAAAGAGGAGGTCTTTAAA
AAGACAATTAAGAGAATTAATATTTTTTATGTTATAGATATTTTCATTTTAAATATTTCTCATTGGTTGAGTGAAGATGA
GCATTTTAATAGTTTTAGCAGTATGCTAGCGACTATTTGTTTCTTGATCTTTATGACGACTCTTTTCTATTTGAAAGCGA
TTCGGGAAAAGTATGAAAAAGAAGAGGAGATTCGACAAAGAGAATTGGAACAGTTGCAGCTGCAGCAGTACACAGATGAA
ATTGTTTCTCTTTATAATGAAATTCGTGGCTTTCGTCATGATTATGCTGGCATGCTGACTAGCTTTCAGACAGCCATCAA
TACGCAAGATATCAAGGAAATTGAAAAAATATATCAAGAAGTTTTAGTCGATGCGAATTTGAAATTACGTTCAGACAAAT
ACACCTATTTTGATTTGAATAATGTTGGTGACTCAGCTCTTCGAAGCGTTATGACAGAGACTTTGTTCAAGGCGCGTGAA
CACCAGATTGATTTGACATTTGAGGTTAAAGAGCCTGTTGAGACATTACCAATTAAGCTATTAGATGTGGTAAGAATGGC
CAGTATTTTGCTAAACAATGCTGTTGAAGGCGCAATTGAAAGCTATGAAAAAATGATTCATGTGACTTTAGTTCAACTCG
ATACAGAAATCATTTTTGTTGTAAAAAATTCCCGCAAGCAAAGAAAATTAGATTTAGAAGAAATTTATAAACCAGAGTTC
TCAACCAAAGGTTATCGAAGAGGCCTAGGTTTAAATAATCTAAAAGAAATTTTAGAGAATTATGAATATATCATGCTGGA
TACAGAAATAAGTAAGTATGATTTCACCCAAGTATTAACAATTAAAAGAAGGAATAGTTTATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(339-441)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

55.27

87.025

0.481
  comD/comD2 Streptococcus gordonii strain NCTC7865

54.145

86.353

0.468
  comD/comD1 Streptococcus pneumoniae Rx1

42.579

91.946

0.391
  comD/comD1 Streptococcus pneumoniae D39

42.579

91.946

0.391
  comD/comD1 Streptococcus pneumoniae R6

42.579

91.946

0.391
  comD Streptococcus mitis NCTC 12261

43.073

88.814

0.383
  comD/comD2 Streptococcus pneumoniae TIGR4

44

83.893

0.369
  comD Streptococcus mitis SK321

42.933

83.893

0.36

Multiple sequence alignment