Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   DQN71_RS05190 Genome accession   NZ_LS483471
Coordinates   1015119..1015793 (+) Length   224 a.a.
NCBI ID   WP_015604895.1    Uniprot ID   A0A512A985
Organism   Streptococcus cristatus strain NCTC13807     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1010119..1020793
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN71_RS05170 (NCTC13807_00989) - 1010775..1011071 (+) 297 WP_015604891.1 hypothetical protein -
  DQN71_RS05175 (NCTC13807_00990) - 1011080..1011400 (+) 321 WP_015604892.1 hypothetical protein -
  DQN71_RS05180 (NCTC13807_00991) - 1011647..1014190 (+) 2544 WP_015604893.1 M1 family metallopeptidase -
  DQN71_RS05185 (NCTC13807_00992) - 1014561..1014998 (+) 438 WP_111694531.1 hypothetical protein -
  DQN71_RS05190 (NCTC13807_00993) ciaR 1015119..1015793 (+) 675 WP_015604895.1 response regulator transcription factor Regulator
  DQN71_RS05195 (NCTC13807_00994) ciaH 1015783..1017147 (+) 1365 WP_015604896.1 sensor histidine kinase Regulator
  DQN71_RS05200 (NCTC13807_00995) - 1017222..1017608 (+) 387 WP_015604897.1 VOC family protein -
  DQN71_RS05205 (NCTC13807_00996) - 1017697..1019094 (+) 1398 WP_015604898.1 polysaccharide deacetylase family protein -
  DQN71_RS05210 (NCTC13807_00997) - 1019176..1020264 (-) 1089 WP_015604899.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25299.00 Da        Isoelectric Point: 4.2907

>NTDB_id=1142315 DQN71_RS05190 WP_015604895.1 1015119..1015793(+) (ciaR) [Streptococcus cristatus strain NCTC13807]
MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLIMTA
KESIDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNENTLSYGDVAVNLSTNSTLVDGKEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTAFANNLQTLRSVGYILKNAE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1142315 DQN71_RS05190 WP_015604895.1 1015119..1015793(+) (ciaR) [Streptococcus cristatus strain NCTC13807]
ATGATTAAGATTCTATTAGTGGAGGATGACCTCGGTCTGTCAAACTCAGTATTTGATTTTTTAGATGATTTTGCAGATGT
TATGCAGGTCTTTGATGGCGAAGAAGGACTATACGAGGCAGAAAGTGGCGTTTATGACCTGATTTTGCTGGACTTGATGT
TGCCTGAAAAGGACGGCTTCCAAGTGCTTAAAGAATTGCGTGAAAAAGGGGTCACCACTCCTGTCCTCATCATGACTGCC
AAGGAAAGTATCGATGATAAAGGCCATGGTTTTGAACTCGGTGCTGACGATTACCTGACTAAGCCTTTTTATCTGGAAGA
GCTTAAAATGCGGATTCAGGCCTTGCTCAAACGCTCTGGTAAGTTTAATGAAAATACCCTGTCCTATGGCGATGTGGCGG
TCAATCTTTCGACCAATTCGACCTTGGTAGACGGAAAAGAAGTGGAACTGCTGGGCAAAGAGTTTGATCTGTTGGTCTAC
TTCCTTCAGAATCAAAATGTCATTTTGCCCAAGACTCAGATCTTCGATCGTTTGTGGGGCTTTGACAGCGATACGACGAT
TTCTGTGGTGGAAGTCTATGTATCTAAGATTCGGAAAAAATTGAAAGGAACGGCTTTTGCGAATAATCTTCAAACCCTTC
GCAGTGTCGGTTACATTTTAAAGAATGCTGAATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

90.625

100

0.906
  ciaR Streptococcus pneumoniae D39

90.625

100

0.906
  ciaR Streptococcus pneumoniae R6

90.625

100

0.906
  ciaR Streptococcus pneumoniae TIGR4

90.625

100

0.906
  ciaR Streptococcus mutans UA159

88.789

99.554

0.884
  covR Lactococcus lactis subsp. lactis strain DGCC12653

39.381

100

0.397
  vicR Streptococcus mutans UA159

35.897

100

0.375
  covR Streptococcus salivarius strain HSISS4

36.283

100

0.366

Multiple sequence alignment