Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DQN30_RS04315 Genome accession   NZ_LS483458
Coordinates   848466..849686 (-) Length   406 a.a.
NCBI ID   WP_111696425.1    Uniprot ID   A0A2X4R409
Organism   Haemophilus haemolyticus strain NCTC10839     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 843466..854686
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN30_RS04290 (NCTC10839_00847) - 845213..845419 (-) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  DQN30_RS04295 (NCTC10839_00848) - 845496..845882 (+) 387 WP_111696423.1 Cu(I)-responsive transcriptional regulator -
  DQN30_RS04300 (NCTC10839_00849) metJ 845896..846213 (-) 318 WP_005634287.1 met regulon transcriptional regulator MetJ -
  DQN30_RS04305 (NCTC10839_00850) rho 846461..847723 (+) 1263 WP_005629550.1 transcription termination factor Rho -
  DQN30_RS04310 (NCTC10839_00851) pilD 847777..848469 (-) 693 WP_111696424.1 A24 family peptidase Machinery gene
  DQN30_RS04315 (NCTC10839_00852) pilC 848466..849686 (-) 1221 WP_111696425.1 type II secretion system F family protein Machinery gene
  DQN30_RS04320 (NCTC10839_00853) pilB 849683..851077 (-) 1395 WP_111696426.1 GspE/PulE family protein Machinery gene
  DQN30_RS04325 (NCTC10839_00854) pilA 851074..851514 (-) 441 WP_111696427.1 prepilin peptidase-dependent pilin Machinery gene
  DQN30_RS04330 (NCTC10839_00855) ampD 851629..852183 (+) 555 WP_111696428.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  DQN30_RS04335 (NCTC10839_00856) rppH 852709..853299 (+) 591 WP_111696429.1 RNA pyrophosphohydrolase -
  DQN30_RS04340 (NCTC10839_00857) - 853299..854096 (+) 798 WP_111696430.1 sulfite exporter TauE/SafE family protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46423.54 Da        Isoelectric Point: 9.9100

>NTDB_id=1142196 DQN30_RS04315 WP_111696425.1 848466..849686(-) (pilC) [Haemophilus haemolyticus strain NCTC10839]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGLTHIRLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLSVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITEILLSISNFLKQNIGILLFFAFSFFLFYYFYLKRQTWF
HQKKNQLLSITPIFGTIQKRSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDIVLDKEVRSILQWVSQG
YAFSNSVSSELFPMEAQQMLQIGEQSGKLSLMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=1142196 DQN30_RS04315 WP_111696425.1 848466..849686(-) (pilC) [Haemophilus haemolyticus strain NCTC10839]
ATGACTAAAAAACTTTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAATTAATAAGCCGCGGCCTTACTCACATCAGATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGCAATTCCGTTAAAAAACAGTCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAATGAATGGCTTGAACGACTACTGCAATCCATTGAATCTGGTTT
AGCATTCTCACAGGCGATTGAACAACAAGGGAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CGGGCAAACTTTCCGTTGTTTGTAAAAAAATAGCCACGCATCGTAGCCAATCTTTAGCATTACAACGCAAATTACAGAAA
ATTATGCTGTACCCCTCAATGGTGTTAGGAATTTCTCTATTATTGACGCTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGTAATAATGCTGAGTTACCAACAATAACCGAAATATTGCTCTCTATATCTAATTTTCTTAAGC
AAAATATTGGGATTTTGCTATTTTTCGCTTTTAGTTTTTTTCTATTTTATTACTTCTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTCCTCTCTATTACGCCTATTTTTGGCACAATTCAAAAGCGTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAGGCCGGCGTACCGCTTAATCAAGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAACCAAGAAAACGCTTGTAAATGACATCGTATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGC
TATGCGTTTTCTAATAGCGTAAGTAGCGAGCTTTTCCCAATGGAAGCACAACAAATGCTCCAAATTGGTGAGCAAAGCGG
AAAACTCTCTTTGATGCTAGAGCATATTGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTGATCATCGGCAGTCTGATTGGGATTATTATGATGGGAATGTATCTCCCTATCTTTAAT
ATGGGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2X4R409

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

96.798

100

0.968
  pilC Haemophilus influenzae Rd KW20

96.552

100

0.966
  pilC Glaesserella parasuis strain SC1401

39.401

98.768

0.389

Multiple sequence alignment