Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   DQN30_RS04310 Genome accession   NZ_LS483458
Coordinates   847777..848469 (-) Length   230 a.a.
NCBI ID   WP_111696424.1    Uniprot ID   A0A2X4RD39
Organism   Haemophilus haemolyticus strain NCTC10839     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 842777..853469
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN30_RS04285 (NCTC10839_00846) - 843067..845238 (-) 2172 WP_111696422.1 cation-translocating P-type ATPase -
  DQN30_RS04290 (NCTC10839_00847) - 845213..845419 (-) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  DQN30_RS04295 (NCTC10839_00848) - 845496..845882 (+) 387 WP_111696423.1 Cu(I)-responsive transcriptional regulator -
  DQN30_RS04300 (NCTC10839_00849) metJ 845896..846213 (-) 318 WP_005634287.1 met regulon transcriptional regulator MetJ -
  DQN30_RS04305 (NCTC10839_00850) rho 846461..847723 (+) 1263 WP_005629550.1 transcription termination factor Rho -
  DQN30_RS04310 (NCTC10839_00851) pilD 847777..848469 (-) 693 WP_111696424.1 A24 family peptidase Machinery gene
  DQN30_RS04315 (NCTC10839_00852) pilC 848466..849686 (-) 1221 WP_111696425.1 type II secretion system F family protein Machinery gene
  DQN30_RS04320 (NCTC10839_00853) pilB 849683..851077 (-) 1395 WP_111696426.1 GspE/PulE family protein Machinery gene
  DQN30_RS04325 (NCTC10839_00854) pilA 851074..851514 (-) 441 WP_111696427.1 prepilin peptidase-dependent pilin Machinery gene
  DQN30_RS04330 (NCTC10839_00855) ampD 851629..852183 (+) 555 WP_111696428.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  DQN30_RS04335 (NCTC10839_00856) rppH 852709..853299 (+) 591 WP_111696429.1 RNA pyrophosphohydrolase -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26715.72 Da        Isoelectric Point: 8.8543

>NTDB_id=1142195 DQN30_RS04310 WP_111696424.1 847777..848469(-) (pilD) [Haemophilus haemolyticus strain NCTC10839]
MIYFAMFLLGGILGIALWFYLSGFITRLQQEIYATYVELFPQNFLSFQPSFSSIQQKKCGHILRYFLSVGVGFIFLQIAF
KDSIFTIWIGLTLLILWAISYLDWDYQLISTTHCLWLLTLGLFGADNNFSLLTLSESIKSAASFFIVFYAIYWIAKFYYR
KEAFGRGDYWLAMALGSFIHLEALPHFLLLASVLGICFSLIHKKKKEFLPFAPFMNLSAIIIYFVKYYGY

Nucleotide


Download         Length: 693 bp        

>NTDB_id=1142195 DQN30_RS04310 WP_111696424.1 847777..848469(-) (pilD) [Haemophilus haemolyticus strain NCTC10839]
ATGATTTACTTCGCAATGTTTTTATTAGGCGGCATCTTAGGGATCGCATTGTGGTTCTACCTATCTGGTTTTATTACTCG
TTTACAGCAAGAGATTTATGCGACTTACGTTGAATTATTTCCACAAAACTTTCTGTCATTTCAGCCTAGCTTTTCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGGTATTTTTTAAGTGTTGGAGTTGGATTTATATTTTTACAAATTGCCTTC
AAAGATTCTATTTTTACTATATGGATCGGACTCACACTTCTTATCCTCTGGGCAATCAGTTATCTTGATTGGGATTATCA
ACTTATTTCTACGACTCACTGTTTATGGTTACTTACTCTCGGTTTATTTGGCGCAGACAATAATTTTTCATTGCTTACGT
TATCTGAAAGCATAAAAAGTGCGGCAAGTTTTTTTATTGTTTTCTACGCAATCTATTGGATTGCAAAATTCTATTACAGA
AAAGAAGCCTTTGGGCGGGGAGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCATTTAGAAGCCTTACCGCACTT
TTTATTATTAGCCTCAGTGCTTGGAATATGTTTTTCGCTTATTCATAAGAAGAAAAAAGAATTTTTACCTTTTGCCCCTT
TTATGAACTTGTCGGCTATCATAATTTATTTCGTCAAATATTACGGATATTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(92-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2X4RD39

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae 86-028NP

92.174

100

0.922
  pilD Haemophilus influenzae Rd KW20

90.87

100

0.909

Multiple sequence alignment