Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   DQK98_RS06090 Genome accession   NZ_LS483449
Coordinates   1164971..1165675 (-) Length   234 a.a.
NCBI ID   WP_000722076.1    Uniprot ID   Q9S1K0
Organism   Streptococcus pneumoniae strain 4041STDY6836170     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1159971..1170675
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQK98_RS06060 - 1160164..1161150 (+) 987 WP_000204727.1 L-lactate dehydrogenase -
  DQK98_RS06065 - 1161439..1162182 (-) 744 Protein_1148 potassium channel family protein -
  DQK98_RS06070 - 1162229..1162483 (-) 255 WP_001809704.1 type II toxin-antitoxin system RelE family toxin -
  DQK98_RS06075 relB 1162485..1162727 (-) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  DQK98_RS06080 vicX 1162818..1163627 (-) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  DQK98_RS06085 micB 1163629..1164978 (-) 1350 WP_001861620.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQK98_RS06090 micA 1164971..1165675 (-) 705 WP_000722076.1 response regulator YycF Regulator
  DQK98_RS06095 mutY 1165731..1166906 (-) 1176 WP_050212015.1 A/G-specific adenine glycosylase -
  DQK98_RS12150 - 1167003..1167128 (+) 126 WP_001818232.1 hypothetical protein -
  DQK98_RS06100 - 1167234..1168904 (-) 1671 WP_111688111.1 formate--tetrahydrofolate ligase -
  DQK98_RS06105 coaB 1169134..1169823 (+) 690 WP_111688112.1 phosphopantothenate--cysteine ligase -
  DQK98_RS06110 coaC 1169835..1170386 (+) 552 WP_001284129.1 phosphopantothenoylcysteine decarboxylase -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26815.63 Da        Isoelectric Point: 4.7164

>NTDB_id=1141902 DQK98_RS06090 WP_000722076.1 1164971..1165675(-) (micA) [Streptococcus pneumoniae strain 4041STDY6836170]
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMRNNA

Nucleotide


Download         Length: 705 bp        

>NTDB_id=1141902 DQK98_RS06090 WP_000722076.1 1164971..1165675(-) (micA) [Streptococcus pneumoniae strain 4041STDY6836170]
ATGAAAAAAATACTAATTGTAGATGATGAGAAACCAATCTCGGATATTATCAAGTTTAATATGACCAAGGAAGGTTACGA
AGTTGTAACTGCTTTTAATGGTCGTGAAGCGCTAGAGCAATTTGAAGCAGAGCAACCAGATATTATTATTCTGGATTTGA
TGCTTCCAGAAATTGATGGTTTAGAAGTTGCTAAGACCATTCGTAAGACAAGCAGTGTGCCCATTCTTATGCTTTCAGCC
AAAGATAGTGAATTTGATAAGGTTATCGGTTTGGAACTTGGGGCAGATGACTATGTAACGAAACCCTTCTCCAATCGTGA
GTTGCAGGCGCGTGTTAAAGCTCTTCTGCGTCGTTCTCAACCTATGCCAGTAGATGGTCAGGAAGCAGATAGTAAACCTC
AACCTATCCAAATTGGGGATTTAGAAATTGTTCCAGACGCCTACGTGGCTAAAAAATATGGCGAAGAACTAGACTTAACC
CATCGTGAATTTGAGCTTTTGTATCATTTAGCATCGCATACAGGTCAAGTCATCACGCGCGAACACTTGCTTGAGACTGT
CTGGGGTTATGACTATTTTGGTGATGTCCGTACAGTTGATGTGACTGTACGACGTCTGCGTGAGAAGATTGAAGATACGC
CCAGCCGACCAGAGTATATCTTGACGCGCCGTGGTGTAGGGTATTACATGAGAAATAATGCTTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 1NXS
  PDB 2A9O
  PDB 2A9P

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

100

100

1
  vicR Streptococcus mutans UA159

78.541

99.573

0.782
  covR Streptococcus salivarius strain HSISS4

44.156

98.718

0.436
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.478

98.291

0.427
  scnR Streptococcus mutans UA159

38.197

99.573

0.38

Multiple sequence alignment