Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   DQK98_RS04735 Genome accession   NZ_LS483449
Coordinates   895268..895918 (+) Length   216 a.a.
NCBI ID   WP_000387343.1    Uniprot ID   A0AAP5J885
Organism   Streptococcus pneumoniae strain 4041STDY6836170     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 890268..900918
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQK98_RS04700 - 890752..890967 (+) 216 WP_001232082.1 YozE family protein -
  DQK98_RS04705 - 891053..892021 (+) 969 WP_000658183.1 PhoH family protein -
  DQK98_RS04715 - 892214..892714 (+) 501 WP_000566981.1 GNAT family N-acetyltransferase -
  DQK98_RS04720 - 892717..893042 (+) 326 Protein_897 TfoX/Sxy family protein -
  DQK98_RS04725 ald 893343..894454 (-) 1112 Protein_898 alanine dehydrogenase -
  DQK98_RS04730 - 894631..895200 (+) 570 WP_000443748.1 GNAT family N-acetyltransferase -
  DQK98_RS04735 comEA/celA/cilE 895268..895918 (+) 651 WP_000387343.1 helix-hairpin-helix domain-containing protein Machinery gene
  DQK98_RS04740 comEC/celB 895902..898142 (+) 2241 WP_111688084.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DQK98_RS04745 - 898551..899138 (+) 588 WP_050205899.1 ATP-binding cassette domain-containing protein -
  DQK98_RS04750 - 899142..900323 (+) 1182 WP_050213313.1 hypothetical protein -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23195.50 Da        Isoelectric Point: 6.0746

>NTDB_id=1141896 DQK98_RS04735 WP_000387343.1 895268..895918(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain 4041STDY6836170]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDSSTEKEVKKEEKEEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=1141896 DQK98_RS04735 WP_000387343.1 895268..895918(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain 4041STDY6836170]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGAGGATT
TTTCCTGCTAAAACCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGACT
CATCGACCGAAAAGGAAGTGAAGAAGGAAGAAAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAACAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATTGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGCCAAGACCATAGAAAAACTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(151-214)

SLBB domain (SLBB)

(76-126)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

99.537

100

0.995
  comEA/celA/cilE Streptococcus mitis NCTC 12261

97.222

100

0.972
  comEA/celA/cilE Streptococcus pneumoniae Rx1

96.759

100

0.968
  comEA/celA/cilE Streptococcus pneumoniae D39

96.759

100

0.968
  comEA/celA/cilE Streptococcus pneumoniae R6

96.759

100

0.968
  comEA/celA/cilE Streptococcus mitis SK321

93.519

100

0.935
  comEA Lactococcus lactis subsp. cremoris KW2

41.778

100

0.435
  comEA Latilactobacillus sakei subsp. sakei 23K

34.335

100

0.37

Multiple sequence alignment