Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   DQK99_RS06130 Genome accession   NZ_LS483448
Coordinates   1151162..1151866 (-) Length   234 a.a.
NCBI ID   WP_000722076.1    Uniprot ID   Q9S1K0
Organism   Streptococcus pneumoniae strain 4041STDY6836167     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1146162..1156866
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQK99_RS06100 relB 1146380..1146622 (-) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  DQK99_RS06105 - 1146699..1147513 (-) 815 Protein_1165 IS5-like element IS1515 family transposase -
  DQK99_RS06115 - 1147689..1148945 (+) 1257 WP_000530078.1 ISL3 family transposase -
  DQK99_RS06120 vicX 1149009..1149818 (-) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  DQK99_RS06125 micB 1149820..1151169 (-) 1350 WP_000886213.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQK99_RS06130 micA 1151162..1151866 (-) 705 WP_000722076.1 response regulator YycF Regulator
  DQK99_RS06135 mutY 1151922..1153097 (-) 1176 WP_000886152.1 A/G-specific adenine glycosylase -
  DQK99_RS12545 - 1153194..1153319 (+) 126 WP_001818232.1 hypothetical protein -
  DQK99_RS06140 - 1153425..1155095 (-) 1671 WP_000845285.1 formate--tetrahydrofolate ligase -
  DQK99_RS06145 coaB 1155325..1156014 (+) 690 WP_000699494.1 phosphopantothenate--cysteine ligase -
  DQK99_RS06150 coaC 1156026..1156577 (+) 552 WP_001284128.1 phosphopantothenoylcysteine decarboxylase -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26815.63 Da        Isoelectric Point: 4.7164

>NTDB_id=1141825 DQK99_RS06130 WP_000722076.1 1151162..1151866(-) (micA) [Streptococcus pneumoniae strain 4041STDY6836167]
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMRNNA

Nucleotide


Download         Length: 705 bp        

>NTDB_id=1141825 DQK99_RS06130 WP_000722076.1 1151162..1151866(-) (micA) [Streptococcus pneumoniae strain 4041STDY6836167]
ATGAAAAAAATACTAATTGTAGATGATGAGAAACCAATCTCGGATATTATCAAGTTTAATATGACCAAGGAAGGTTACGA
AGTTGTAACTGCTTTTAATGGTCGTGAAGCGCTAGAGCAATTTGAAGCAGAGCAACCAGATATTATTATTCTGGATTTGA
TGCTTCCAGAAATTGATGGTTTAGAAGTTGCTAAGACCATTCGTAAGACAAGCAGTGTGCCCATTCTTATGCTTTCAGCC
AAAGATAGTGAATTTGATAAGGTTATCGGTTTGGAACTTGGGGCAGATGACTATGTAACGAAACCCTTCTCCAATCGTGA
GTTGCAGGCGCGTGTTAAAGCTCTTCTGCGTCGTTCTCAACCTATGCCAGTAGATGGTCAGGAAGCAGATAGTAAACCTC
AACCTATCCAAATTGGGGATTTAGAAATTGTTCCAGACGCCTACGTGGCTAAAAAATATGGCGAAGAACTAGACTTAACC
CATCGTGAATTTGAGCTTTTGTATCATTTAGCATCGCATACAGGTCAAGTCATCACGCGCGAACACTTGCTTGAGACTGT
CTGGGGTTATGACTATTTTGGTGATGTCCGTACAGTTGATGTGACTGTACGACGTCTGCGTGAGAAGATTGAAGATACGC
CCAGCCGACCAGAGTATATCTTGACGCGCCGTGGTGTAGGGTATTACATGAGAAATAATGCTTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 1NXS
  PDB 2A9O
  PDB 2A9P

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

100

100

1
  vicR Streptococcus mutans UA159

78.541

99.573

0.782
  covR Streptococcus salivarius strain HSISS4

44.156

98.718

0.436
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.478

98.291

0.427
  scnR Streptococcus mutans UA159

38.197

99.573

0.38

Multiple sequence alignment