Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   DQL20_RS10580 Genome accession   NZ_LS483444
Coordinates   2124999..2127152 (-) Length   717 a.a.
NCBI ID   WP_006595359.1    Uniprot ID   E7S8Q8
Organism   Streptococcus australis strain NCTC13166     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 2119999..2132152
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL20_RS10570 (NCTC11371_02057) - 2122762..2123298 (+) 537 WP_006595361.1 TetR/AcrR family transcriptional regulator -
  DQL20_RS10575 (NCTC11371_02058) comB 2123610..2124971 (-) 1362 WP_006595360.1 bacteriocin secretion accessory protein Regulator
  DQL20_RS10580 (NCTC11371_02059) comA 2124999..2127152 (-) 2154 WP_006595359.1 peptide cleavage/export ABC transporter ComA Regulator
  DQL20_RS10585 (NCTC11371_02060) rpsD 2127435..2128046 (-) 612 WP_003009175.1 30S ribosomal protein S4 -
  DQL20_RS10590 (NCTC11371_02061) - 2128644..2128916 (-) 273 WP_006595358.1 Veg family protein -
  DQL20_RS10595 (NCTC11371_02062) dnaB 2128920..2130275 (-) 1356 WP_006596978.1 replicative DNA helicase -
  DQL20_RS10600 (NCTC11371_02063) rplI 2130300..2130752 (-) 453 WP_006596977.1 50S ribosomal protein L9 -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 81021.58 Da        Isoelectric Point: 8.5372

>NTDB_id=1141763 DQL20_RS10580 WP_006595359.1 2124999..2127152(-) (comA) [Streptococcus australis strain NCTC13166]
MGFKKKHYRQQVDMRDCGVAALAMVFGYYGSYYSLASLREKAKTTADGTTALGLVKVAEELGFETRAFRADRTLFDLEGV
TYPLIVHVIKDGRLPHYYVVYKKDKKYLYIADPDPKVKMTKLTIEEFEKEWTGIVIALAPTPAYQPSKEKKNGLLDFVPL
LFKQRQLVLHIVLATLLVTLINIVGSYYLQSIIDTYVPDQMKQTLSVISLGLIVVYILQQVLTYAQDYLLLVLGQRLSID
VILSYIKHVFQLPMSFFATRRTGEVVSRFTDANRIIDALASTLLSIFLDLSIVLILSVVLFSQNAHLFFLTILLLPIYAV
IIFAFMKPFERLNNETMEANSVLSSSIIEDINGIETIKSLTSERSRYQKIDTEFVDYLKKSFAMSKAESLQKGLKHLAQL
ILNVLVLWMGAHLVMKQELSLGQLITYNTLLVYFTGPLENLINLQTKLQAARVANTRLNEVYLIDSEFAEKKPLQERETL
DGDLVFEGVDYKYGFGANVLTDINLRIKKGSKVSFVGISGSGKTTLAKMMVNFYQPNKGTIRLGGTDIQQVDKTLLRQQI
NYLPQQPYVFNGTILENLLLGAREGTSQEDILRAVEIAGIREDIERMPLNYQTELTTDGMGISGGQRQRIALARALLTDA
PILILDEATSSLDILTEKKIVDRLMALDKTIIFIAHRLTIAERSEKVFLLDQGRLKEEGSHEELLKKNGYYSHLVTC

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=1141763 DQL20_RS10580 WP_006595359.1 2124999..2127152(-) (comA) [Streptococcus australis strain NCTC13166]
ATGGGATTTAAGAAAAAACATTATCGCCAACAAGTTGACATGAGAGATTGCGGTGTTGCAGCTTTAGCCATGGTCTTTGG
TTACTATGGATCATACTATTCTTTAGCTAGTCTGAGGGAGAAGGCAAAAACGACTGCAGATGGAACGACCGCCTTAGGTC
TGGTCAAGGTGGCTGAGGAGTTGGGATTTGAGACACGCGCCTTCCGAGCAGACCGCACACTTTTTGACTTGGAAGGAGTG
ACCTATCCATTGATTGTCCACGTGATCAAGGATGGGCGTCTCCCTCACTATTACGTAGTCTATAAGAAAGATAAAAAGTA
TCTTTACATAGCAGATCCAGATCCAAAGGTAAAGATGACCAAATTGACGATCGAAGAGTTTGAAAAGGAATGGACAGGGA
TTGTCATTGCCCTGGCCCCGACTCCAGCCTATCAACCGAGTAAAGAAAAGAAAAATGGGCTCCTAGACTTTGTCCCTCTT
TTGTTTAAACAGCGGCAATTGGTTCTGCATATTGTTCTTGCAACGTTATTGGTGACCCTCATCAATATTGTGGGTTCTTA
CTACTTACAATCGATTATTGATACCTATGTGCCTGATCAGATGAAGCAGACGCTGAGTGTGATTTCACTAGGGTTGATCG
TGGTTTACATCTTACAGCAAGTCCTGACCTATGCGCAAGATTACTTGCTTCTTGTTTTAGGCCAACGCTTGTCTATAGAT
GTCATTCTATCCTATATTAAGCATGTTTTTCAGTTGCCTATGAGTTTCTTTGCAACTCGACGGACAGGAGAAGTGGTGTC
GCGGTTTACAGATGCCAACCGGATTATCGATGCTCTGGCTAGTACGTTGCTTTCAATCTTTTTGGATCTGTCTATTGTTT
TGATTTTATCAGTAGTCCTGTTTAGCCAAAATGCTCATCTCTTTTTCTTGACCATTCTCTTACTGCCGATTTATGCGGTC
ATTATTTTTGCCTTTATGAAGCCTTTTGAGCGCTTAAATAATGAAACCATGGAAGCCAATAGTGTCTTGTCTTCTTCTAT
TATCGAAGATATCAATGGGATTGAAACCATCAAGTCTCTGACCAGTGAGCGTAGTCGTTATCAAAAGATTGACACAGAAT
TTGTGGATTATCTGAAGAAGTCCTTTGCCATGAGCAAGGCGGAGAGTCTTCAAAAGGGGCTCAAGCACTTGGCCCAGTTG
ATTTTGAATGTCTTGGTCTTGTGGATGGGAGCTCATTTGGTCATGAAGCAAGAATTGAGTTTGGGTCAGCTGATTACCTA
CAATACTCTCCTTGTTTACTTCACAGGGCCTCTAGAGAATTTGATCAACCTCCAAACTAAACTGCAAGCAGCCCGAGTGG
CCAATACACGTCTGAATGAAGTCTATTTGATAGACTCTGAGTTCGCAGAGAAGAAGCCTCTTCAAGAGCGTGAGACTCTC
GATGGTGATCTGGTTTTTGAGGGAGTGGACTACAAGTACGGTTTTGGAGCCAATGTTTTAACAGATATTAACTTAAGGAT
CAAAAAAGGGAGCAAGGTGAGTTTTGTCGGTATTTCCGGTTCTGGAAAAACCACGCTAGCAAAGATGATGGTGAATTTCT
ACCAACCCAATAAAGGGACGATTCGTCTGGGAGGAACGGATATCCAGCAAGTCGATAAAACTTTGCTCCGCCAGCAAATC
AATTATTTACCCCAGCAGCCCTATGTCTTTAATGGTACGATTTTAGAGAACTTGTTACTGGGAGCGCGGGAAGGAACCAG
TCAGGAAGATATTTTGCGCGCGGTTGAAATCGCAGGAATTCGAGAAGACATTGAGCGCATGCCCCTCAATTACCAAACGG
AATTGACTACGGATGGCATGGGAATTTCTGGTGGACAACGGCAGCGGATTGCCTTGGCGCGTGCCTTATTAACGGATGCT
CCGATTCTGATTCTGGATGAAGCGACCAGTAGCCTGGATATCTTGACGGAGAAGAAAATTGTGGACCGCTTGATGGCCTT
AGATAAAACCATTATCTTTATTGCCCACCGGTTAACGATTGCAGAGCGTTCTGAAAAAGTCTTCCTCCTGGACCAAGGTC
GTCTGAAAGAAGAAGGAAGTCATGAAGAACTGCTGAAAAAGAATGGTTATTACAGCCATTTGGTAACTTGTTAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(171-438)

Peptidase C39 family (Peptidase_C39)

(6-142)

ABC transporter (ABC_tran)

(500-650)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E7S8Q8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

77.266

100

0.773
  comA Streptococcus mitis NCTC 12261

75.314

100

0.753
  comA Streptococcus pneumoniae Rx1

75.174

100

0.752
  comA Streptococcus pneumoniae D39

75.174

100

0.752
  comA Streptococcus pneumoniae R6

75.174

100

0.752
  comA Streptococcus mitis SK321

75.174

100

0.752
  comA Streptococcus pneumoniae TIGR4

74.756

100

0.748
  comA/nlmT Streptococcus mutans UA159

63.497

99.721

0.633

Multiple sequence alignment