Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   DQL20_RS07735 Genome accession   NZ_LS483444
Coordinates   1470159..1470860 (-) Length   233 a.a.
NCBI ID   WP_006595891.1    Uniprot ID   E7SBS4
Organism   Streptococcus australis strain NCTC13166     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1465159..1475860
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL20_RS07715 (NCTC11371_01509) rnc 1466695..1467396 (-) 702 WP_006596983.1 ribonuclease III -
  DQL20_RS07720 (NCTC11371_01510) - 1467555..1467944 (-) 390 WP_006595894.1 YbaN family protein -
  DQL20_RS07725 (NCTC11371_01511) vicX 1468002..1468811 (-) 810 WP_006595893.1 MBL fold metallo-hydrolase Regulator
  DQL20_RS07730 (NCTC11371_01512) micB 1468820..1470166 (-) 1347 WP_006595892.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQL20_RS07735 (NCTC11371_01513) micA 1470159..1470860 (-) 702 WP_006595891.1 response regulator YycF Regulator
  DQL20_RS07740 (NCTC11371_01514) - 1471436..1472485 (+) 1050 WP_006595890.1 DUF389 domain-containing protein -
  DQL20_RS07745 (NCTC11371_01515) tnpA 1472768..1473232 (-) 465 WP_006596946.1 IS200/IS605 family transposase -
  DQL20_RS07750 (NCTC11371_01516) thrS 1473454..1475397 (-) 1944 WP_006595889.1 threonine--tRNA ligase -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26645.57 Da        Isoelectric Point: 4.7260

>NTDB_id=1141753 DQL20_RS07735 WP_006595891.1 1470159..1470860(-) (micA) [Streptococcus australis strain NCTC13166]
MKKILVVDDEKPISDIIKFNMAKEGYEVLTAFDGKEALAVFEAESPDILILDLMLPEIDGLEVARTIRKTSNVPIIVLSA
KDTEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRTELTVESQTESTSDSDIVIGDLKIIPDTFLAQKKGKELELTH
REFELLYHLATHVGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPGRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=1141753 DQL20_RS07735 WP_006595891.1 1470159..1470860(-) (micA) [Streptococcus australis strain NCTC13166]
ATGAAGAAAATTCTTGTTGTAGATGATGAAAAGCCGATTTCTGATATTATAAAATTCAATATGGCCAAAGAAGGCTATGA
AGTCTTGACTGCCTTCGATGGAAAAGAAGCACTGGCTGTTTTCGAAGCTGAGAGCCCAGATATTTTGATCTTGGACCTCA
TGCTTCCTGAAATTGATGGTTTGGAAGTAGCGCGTACCATTCGAAAGACCAGTAATGTACCGATTATTGTCTTATCTGCA
AAAGATACAGAATTTGATAAGGTTATCGGTCTTGAAATTGGTGCGGATGACTATGTGACTAAGCCATTCTCAAATCGTGA
GCTTCAAGCTCGCGTAAAAGCTTTGTTGCGTCGGACAGAACTAACGGTAGAATCACAGACAGAGTCTACATCAGATTCAG
ATATTGTGATTGGTGATTTGAAAATCATTCCGGATACCTTCCTTGCTCAGAAAAAAGGCAAAGAGCTCGAGTTGACCCAT
CGCGAATTTGAGTTGCTCTATCACTTGGCGACCCATGTAGGCCAAGTCATGACCCGTGAGCATTTGCTGGAAACAGTCTG
GGGCTACGATTATTTTGGGGATGTTCGGACAGTGGACGTAACGATTCGACGTTTGCGTGAAAAAATCGAAGATATTCCAG
GCCGTCCGGAGTATATTTTAACGCGCCGCGGTGTCGGTTACTATATGAGAAACAATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E7SBS4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

80.258

100

0.803
  vicR Streptococcus mutans UA159

77.119

100

0.781
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.69

99.571

0.455
  covR Streptococcus salivarius strain HSISS4

41.048

98.283

0.403

Multiple sequence alignment