Detailed information NTG1141752

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: DQL20_RS07730
• Genome accession: NZ_LS483444
• Coordinates: 1468820..1470166 (-)
• Length: 448 a.a.
• NCBI ID: WP_006595892.1
• Uniprot ID: E7SBS5
• Organism: Streptococcus australis strain NCTC13166
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1463820..1475166

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL20_RS07715 (NCTC11371_01509)	rnc	1466695..1467396 (-)	702	WP_006596983.1	ribonuclease III	-
DQL20_RS07720 (NCTC11371_01510)	-	1467555..1467944 (-)	390	WP_006595894.1	YbaN family protein	-
DQL20_RS07725 (NCTC11371_01511)	vicX	1468002..1468811 (-)	810	WP_006595893.1	MBL fold metallo-hydrolase	Regulator
DQL20_RS07730 (NCTC11371_01512)	micB	1468820..1470166 (-)	1347	WP_006595892.1	cell wall metabolism sensor histidine kinase VicK	Regulator
DQL20_RS07735 (NCTC11371_01513)	micA	1470159..1470860 (-)	702	WP_006595891.1	response regulator YycF	Regulator
DQL20_RS07740 (NCTC11371_01514)	-	1471436..1472485 (+)	1050	WP_006595890.1	DUF389 domain-containing protein	-
DQL20_RS07745 (NCTC11371_01515)	tnpA	1472768..1473232 (-)	465	WP_006596946.1	IS200/IS605 family transposase	-

Sequence

Protein

• Length: 448 a.a.
• Molecular weight: 50773.09 Da
• Isoelectric Point: 4.5931

>NTDB_id=1141752 DQL20_RS07730 WP_006595892.1 1468820..1470166(-) (micB) [Streptococcus australis strain NCTC13166]
MINHIKEVMTSYNFVFILLTLGFIIVVALLILENRRDNMKLRLLNDKIKSLIAGEYSDIIDLQGGPELTEISNNINDLSE
VIRLTHENLEQETKRLTSILSYMTDGVLATNRRGQIILVNEMAAKQLNVVVEEVMNISILDLLGISEEYELRDLITNVPE
LTIDSQDENGEYISLRVRFALIRRESGFISGLVAVLHDTTEQDKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGAIS
EPVAPEFVKVSLTETNRMMRMVTDLLSLSRIDNETSQLDVELTNFTAFITFILNRFDKMKSQAGEKKYDIVRDYPISPVW
VEIDTDKMTQVLDNILNNAIKYSPDGGEIRVGMKTTDAQLIISISDEGLGIPKKDLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAILDDGWDNEGE

Nucleotide

• Length: 1347 bp

>NTDB_id=1141752 DQL20_RS07730 WP_006595892.1 1468820..1470166(-) (micB) [Streptococcus australis strain NCTC13166]
ATGATTAATCACATCAAAGAAGTCATGACCTCTTATAATTTTGTTTTTATATTACTCACTCTTGGGTTTATTATCGTGGT
GGCCTTGCTGATTCTAGAAAATCGTCGGGATAACATGAAGCTACGCTTGTTGAATGATAAAATTAAGAGTTTGATTGCTG
GAGAATATTCCGATATCATTGATTTACAAGGAGGTCCTGAATTGACAGAGATTTCCAACAATATCAATGATTTATCAGAA
GTTATCCGTTTGACTCATGAAAATTTGGAGCAAGAAACCAAGCGCTTGACCAGCATTCTTTCCTATATGACAGATGGGGT
TTTAGCGACCAATCGTCGTGGGCAGATTATCCTGGTCAATGAAATGGCTGCCAAACAACTTAATGTCGTGGTCGAAGAGG
TCATGAACATCAGTATTCTGGATTTGCTTGGTATTAGTGAAGAGTATGAACTGCGAGACTTGATTACCAATGTTCCGGAA
CTGACTATCGATTCGCAGGATGAAAATGGGGAGTACATCTCTTTACGGGTTCGCTTCGCCTTGATTCGGAGAGAGTCTGG
TTTCATTTCTGGTCTAGTTGCCGTTTTGCATGATACAACCGAACAGGATAAGGAAGAGCGGGAACGTCGTTTATTCGTAT
CCAACGTAAGTCATGAACTCCGAACACCGCTGACCAGTGTCAAATCCTACTTGGAAGCCTTGGATGATGGGGCCATTTCG
GAACCAGTCGCACCGGAATTTGTCAAAGTATCTTTGACAGAGACCAACCGGATGATGCGGATGGTGACGGATTTATTGAG
TCTTTCACGGATTGATAATGAAACCAGTCAATTGGATGTTGAATTGACCAACTTTACAGCCTTTATCACCTTCATTTTGA
ATCGATTCGATAAGATGAAGAGTCAGGCTGGAGAGAAGAAATATGATATTGTTCGTGATTATCCCATTTCTCCTGTCTGG
GTTGAAATTGACACAGATAAGATGACGCAGGTTTTAGACAATATCTTAAATAACGCCATTAAATATTCCCCAGATGGTGG
GGAAATTCGTGTGGGAATGAAAACGACAGATGCCCAGTTGATTATCTCGATTTCGGATGAGGGCTTAGGGATTCCTAAAA
AGGACCTCCCACGAATTTTTGACCGCTTTTATCGCGTGGATAAGGCACGTAGTCGCGCCCAGGGTGGGACTGGTTTAGGA
CTGGCCATTGCCAAGGAAATTATCAAGCAGCACAAAGGATTTATCTGGGCCAAGAGTGAATATGGAAAAGGTTCTACTTT
CACGATTGTTCTACCATATGATAAAGATGCTATCCTAGATGATGGATGGGATAATGAAGGTGAATAA

Domains

Predicted by InterproScan.

• PAS fold (PAS) (96-198)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

3D structure

• AlphaFold DB: E7SBS5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	78.082	97.768	0.763
vicK	Streptococcus mutans UA159	71.182	90.625	0.645