Detailed information NTG1141659

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQN35_RS04915
• Genome accession: NZ_LS483442
• Coordinates: 930442..931278 (-)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC8370
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 925442..936278

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN35_RS04890 (NCTC8370_00969)	-	925684..926676 (-)	993	WP_010922317.1	D-lactate dehydrogenase	-
DQN35_RS04895 (NCTC8370_00970)	-	926691..927236 (-)	546	Protein_889	PTS sugar transporter subunit IIC	-
DQN35_RS09270	-	927249..928131 (+)	883	Protein_890	LysR family transcriptional regulator	-
DQN35_RS04910 (NCTC8370_00972)	topA	928206..930335 (-)	2130	WP_010922315.1	type I DNA topoisomerase	-
DQN35_RS04915 (NCTC8370_00973)	dprA	930442..931278 (-)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
DQN35_RS04920 (NCTC8370_00974)	-	931343..932134 (-)	792	WP_011285534.1	ribonuclease HII	-
DQN35_RS04925 (NCTC8370_00975)	ylqF	932124..932972 (-)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
DQN35_RS04930 (NCTC8370_00976)	-	933191..933631 (+)	441	WP_002989774.1	DUF1836 domain-containing protein	-
DQN35_RS04935 (NCTC8370_00977)	trhA	933628..934278 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DQN35_RS04940 (NCTC8370_00978)	-	934395..935306 (+)	912	WP_010922311.1	diacylglycerol/lipid kinase family protein	-
DQN35_RS04945 (NCTC8370_00979)	-	935356..935724 (-)	369	WP_010922310.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=1141659 DQN35_RS04915 WP_010922314.1 930442..931278(-) (dprA) [Streptococcus pyogenes strain NCTC8370]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1141659 DQN35_RS04915 WP_010922314.1 930442..931278(-) (dprA) [Streptococcus pyogenes strain NCTC8370]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367