Detailed information NTG1141334

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQN32_RS04990
• Genome accession: NZ_LS483432
• Coordinates: 938354..939190 (+)
• Length: 278 a.a.
• NCBI ID: WP_031488274.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC13745
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 933354..944190

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN32_RS04960 (NCTC13745_00985)	-	933839..934276 (+)	438	WP_031488279.1	hypothetical protein	-
DQN32_RS04965 (NCTC13745_00986)	-	934326..935237 (-)	912	WP_031488278.1	diacylglycerol/lipid kinase family protein	-
DQN32_RS04970 (NCTC13745_00987)	trhA	935354..936004 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DQN32_RS04975 (NCTC13745_00988)	-	936001..936441 (-)	441	WP_031488277.1	DUF1836 domain-containing protein	-
DQN32_RS04980 (NCTC13745_00989)	ylqF	936660..937508 (+)	849	WP_031488276.1	ribosome biogenesis GTPase YlqF	-
DQN32_RS04985 (NCTC13745_00990)	-	937498..938289 (+)	792	WP_031488275.1	ribonuclease HII	-
DQN32_RS04990 (NCTC13745_00991)	dprA	938354..939190 (+)	837	WP_031488274.1	DNA-processing protein DprA	Machinery gene
DQN32_RS04995 (NCTC13745_00992)	topA	939297..941426 (+)	2130	WP_011017773.1	type I DNA topoisomerase	-
DQN32_RS09460	-	941501..942358 (-)	858	Protein_914	LysR family transcriptional regulator	-
DQN32_RS05010 (NCTC13745_00994)	-	942398..942943 (+)	546	Protein_915	PTS sugar transporter subunit IIC	-
DQN32_RS05015 (NCTC13745_00995)	-	942958..943950 (+)	993	WP_031488271.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30960.96 Da
• Isoelectric Point: 9.2511

>NTDB_id=1141334 DQN32_RS04990 WP_031488274.1 938354..939190(+) (dprA) [Streptococcus pyogenes strain NCTC13745]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1141334 DQN32_RS04990 WP_031488274.1 938354..939190(+) (dprA) [Streptococcus pyogenes strain NCTC13745]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGCTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGATAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363