Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   DQN36_RS06935 Genome accession   NZ_LS483425
Coordinates   1388709..1389419 (-) Length   236 a.a.
NCBI ID   WP_002985645.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC13737     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1383709..1394419
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN36_RS06920 (NCTC13737_01370) rnc 1385416..1386108 (-) 693 WP_002990670.1 ribonuclease III -
  DQN36_RS06925 (NCTC13737_01371) vicX 1386551..1387360 (-) 810 WP_002985641.1 MBL fold metallo-hydrolase Regulator
  DQN36_RS06930 (NCTC13737_01372) vicK 1387364..1388716 (-) 1353 WP_002995609.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQN36_RS06935 (NCTC13737_01373) vicR 1388709..1389419 (-) 711 WP_002985645.1 response regulator YycF Regulator
  DQN36_RS06940 (NCTC13737_01374) - 1389581..1390615 (-) 1035 WP_162472284.1 DUF3114 domain-containing protein -
  DQN36_RS06945 (NCTC13737_01375) - 1390671..1391918 (-) 1248 WP_010921989.1 AMP-binding protein -
  DQN36_RS06950 (NCTC13737_01376) - 1391875..1393023 (-) 1149 WP_111704296.1 acetyl-CoA C-acyltransferase -
  DQN36_RS06955 (NCTC13737_01377) - 1393437..1394222 (-) 786 WP_023078781.1 ABC transporter permease -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27083.99 Da        Isoelectric Point: 4.9038

>NTDB_id=1141155 DQN36_RS06935 WP_002985645.1 1388709..1389419(-) (vicR) [Streptococcus pyogenes strain NCTC13737]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGTQELTIGNLQILPDAFVAKKHGQEVE
LTHREFELLHHLANHMGQVMTREHLLEIVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1141155 DQN36_RS06935 WP_002985645.1 1388709..1389419(-) (vicR) [Streptococcus pyogenes strain NCTC13737]
ATGAAAAAAATACTTATTGTGGATGATGAAAAACCGATTTCTGACATTATTAAGTTTAATTTGACAAAAGAAGGTTATGA
CATTGTTACAGCTTTTGATGGACGCGAAGCGGTAACAATTTTTGAAGAAGAAAAGCCAGATTTAATTATTCTTGATTTGA
TGCTCCCTGAGTTGGACGGTCTTGAAGTAGCCAAGGAAATTCGTAAAACCAGTCATGTCCCGATTATTATGTTGTCGGCT
AAAGATAGTGAGTTTGACAAGGTTATTGGACTTGAAATTGGGGCTGATGATTACGTGACCAAGCCCTTTTCTAATCGGGA
ATTGCTGGCACGTGTCAAGGCTCATCTGCGTCGTACCGAAACTATTGAAACGGCTGTTGCAGAAGAAAATGCTTCTTCAG
GTACACAGGAACTAACCATTGGTAATTTACAGATTTTACCAGATGCGTTTGTTGCTAAAAAACATGGTCAAGAGGTAGAG
TTGACCCATCGTGAATTTGAACTATTGCATCATCTAGCTAACCATATGGGTCAGGTGATGACACGAGAACACTTATTGGA
AATTGTTTGGGGATATGATTATTTTGGCGATGTGCGCACGGTTGATGTGACTGTTCGTCGTCTCCGTGAAAAAATTGAAG
ACACACCAAGTCGTCCTGAGTATATTTTAACAAGACGTGGTGTTGGGTACTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.254

100

0.903
  micA Streptococcus pneumoniae Cp1015

79.06

99.153

0.784
  covR Streptococcus salivarius strain HSISS4

44.828

98.305

0.441
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

36.91

98.729

0.364

Multiple sequence alignment