Detailed information NTG1141148

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQN36_RS04705
• Genome accession: NZ_LS483425
• Coordinates: 930514..931350 (-)
• Length: 278 a.a.
• NCBI ID: WP_111704191.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC13737
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 925514..936350

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN36_RS04680 (NCTC13737_00920)	-	925733..926724 (-)	992	Protein_836	D-lactate dehydrogenase	-
DQN36_RS04685 (NCTC13737_00921)	-	926739..927305 (-)	567	Protein_837	PTS sugar transporter subunit IIC	-
DQN36_RS09095	-	927318..928202 (+)	885	Protein_838	LysR family transcriptional regulator	-
DQN36_RS04700 (NCTC13737_00923)	topA	928277..930406 (-)	2130	WP_111704190.1	type I DNA topoisomerase	-
DQN36_RS04705 (NCTC13737_00924)	dprA	930514..931350 (-)	837	WP_111704191.1	DNA-processing protein DprA	Machinery gene
DQN36_RS04710 (NCTC13737_00925)	-	931415..932206 (-)	792	WP_031488275.1	ribonuclease HII	-
DQN36_RS04715 (NCTC13737_00926)	ylqF	932196..933044 (-)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
DQN36_RS04720 (NCTC13737_00927)	-	933263..933703 (+)	441	WP_002989774.1	DUF1836 domain-containing protein	-
DQN36_RS04725 (NCTC13737_00928)	trhA	933700..934350 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DQN36_RS04730 (NCTC13737_00929)	-	934467..935378 (+)	912	WP_032460107.1	diacylglycerol/lipid kinase family protein	-
DQN36_RS04735 (NCTC13737_00930)	-	935428..935862 (-)	435	WP_111704192.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31005.88 Da
• Isoelectric Point: 8.3312

>NTDB_id=1141148 DQN36_RS04705 WP_111704191.1 930514..931350(-) (dprA) [Streptococcus pyogenes strain NCTC13737]
MNHFELYELKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGSTCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1141148 DQN36_RS04705 WP_111704191.1 930514..931350(-) (dprA) [Streptococcus pyogenes strain NCTC13737]
GTGAATCATTTTGAACTTTATGAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGATCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363