Detailed information NTG1141060

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQN31_RS04690
• Genome accession: NZ_LS483421
• Coordinates: 909156..909992 (-)
• Length: 278 a.a.
• NCBI ID: WP_014407585.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC10877
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 904156..914992

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN31_RS04665 (NCTC10877_00925)	-	904374..905366 (-)	993	WP_009880715.1	D-lactate dehydrogenase	-
DQN31_RS04670 (NCTC10877_00926)	-	905381..905947 (-)	567	Protein_838	PTS sugar transporter subunit IIC	-
DQN31_RS09065	-	905987..906844 (+)	858	Protein_839	LysR family transcriptional regulator	-
DQN31_RS04685 (NCTC10877_00928)	topA	906919..909048 (-)	2130	WP_014407586.1	type I DNA topoisomerase	-
DQN31_RS04690 (NCTC10877_00929)	dprA	909156..909992 (-)	837	WP_014407585.1	DNA-processing protein DprA	Machinery gene
DQN31_RS04695 (NCTC10877_00930)	-	910057..910848 (-)	792	WP_002995007.1	ribonuclease HII	-
DQN31_RS04700 (NCTC10877_00931)	ylqF	910838..911686 (-)	849	WP_014407584.1	ribosome biogenesis GTPase YlqF	-
DQN31_RS04705 (NCTC10877_00932)	-	911905..912345 (+)	441	WP_014407583.1	DUF1836 domain-containing protein	-
DQN31_RS04710 (NCTC10877_00933)	trhA	912342..912992 (+)	651	WP_014407582.1	PAQR family membrane homeostasis protein TrhA	-
DQN31_RS04715 (NCTC10877_00934)	-	913109..914020 (+)	912	WP_002989777.1	diacylglycerol/lipid kinase family protein	-
DQN31_RS04720 (NCTC10877_00935)	-	914070..914441 (-)	372	WP_014407581.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30988.94 Da
• Isoelectric Point: 8.8230

>NTDB_id=1141060 DQN31_RS04690 WP_014407585.1 909156..909992(-) (dprA) [Streptococcus pyogenes strain NCTC10877]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1141060 DQN31_RS04690 WP_014407585.1 909156..909992(-) (dprA) [Streptococcus pyogenes strain NCTC10877]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367