Detailed information NTG1141008

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQN75_RS04680
• Genome accession: NZ_LS483420
• Coordinates: 908783..909619 (-)
• Length: 278 a.a.
• NCBI ID: WP_002989770.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC13739
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 903783..914619

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN75_RS04655	-	904114..905110 (-)	997	Protein_839	D-lactate dehydrogenase	-
DQN75_RS04660 (NCTC13739_00933)	-	905125..905679 (-)	555	Protein_840	PTS sugar transporter subunit IIC	-
DQN75_RS09020 (NCTC13739_00934)	-	905731..906472 (+)	742	Protein_841	LysR family transcriptional regulator	-
DQN75_RS04675 (NCTC13739_00935)	topA	906547..908676 (-)	2130	WP_111684890.1	type I DNA topoisomerase	-
DQN75_RS04680 (NCTC13739_00936)	dprA	908783..909619 (-)	837	WP_002989770.1	DNA-processing protein DprA	Machinery gene
DQN75_RS04685 (NCTC13739_00937)	-	909684..910475 (-)	792	WP_030125931.1	ribonuclease HII	-
DQN75_RS04690 (NCTC13739_00938)	ylqF	910465..911313 (-)	849	WP_030125932.1	ribosome biogenesis GTPase YlqF	-
DQN75_RS04695 (NCTC13739_00939)	-	911532..911972 (+)	441	WP_011017769.1	DUF1836 domain-containing protein	-
DQN75_RS04700 (NCTC13739_00940)	trhA	911969..912619 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DQN75_RS04705 (NCTC13739_00941)	-	912736..913647 (+)	912	WP_002989777.1	diacylglycerol/lipid kinase family protein	-
DQN75_RS04710 (NCTC13739_00942)	-	913697..914071 (-)	375	WP_023611058.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30956.84 Da
• Isoelectric Point: 8.5841

>NTDB_id=1141008 DQN75_RS04680 WP_002989770.1 908783..909619(-) (dprA) [Streptococcus pyogenes strain NCTC13739]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1141008 DQN75_RS04680 WP_002989770.1 908783..909619(-) (dprA) [Streptococcus pyogenes strain NCTC13739]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATAGAATTTAAACAGTTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367