Detailed information NTG1140818

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQN57_RS04505
• Genome accession: NZ_LS483415
• Coordinates: 863283..864119 (+)
• Length: 278 a.a.
• NCBI ID: WP_111705614.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC8304
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 858283..869119

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN57_RS04475 (NCTC8304_00887)	-	858705..859205 (+)	501	WP_111705611.1	hypothetical protein	-
DQN57_RS04480 (NCTC8304_00888)	-	859255..860166 (-)	912	WP_111705612.1	diacylglycerol/lipid kinase family protein	-
DQN57_RS04485 (NCTC8304_00889)	trhA	860283..860933 (-)	651	WP_111705613.1	PAQR family membrane homeostasis protein TrhA	-
DQN57_RS04490 (NCTC8304_00890)	-	860930..861370 (-)	441	WP_011017769.1	DUF1836 domain-containing protein	-
DQN57_RS04495 (NCTC8304_00891)	ylqF	861589..862437 (+)	849	WP_011017770.1	ribosome biogenesis GTPase YlqF	-
DQN57_RS04500 (NCTC8304_00892)	-	862427..863218 (+)	792	WP_011017771.1	ribonuclease HII	-
DQN57_RS04505 (NCTC8304_00893)	dprA	863283..864119 (+)	837	WP_111705614.1	DNA-processing protein DprA	Machinery gene
DQN57_RS04510 (NCTC8304_00894)	topA	864227..866356 (+)	2130	WP_111705615.1	type I DNA topoisomerase	-
DQN57_RS04515 (NCTC8304_00895)	trmFO	866491..867837 (+)	1347	WP_111705616.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31114.11 Da
• Isoelectric Point: 9.0334

>NTDB_id=1140818 DQN57_RS04505 WP_111705614.1 863283..864119(+) (dprA) [Streptococcus pyogenes strain NCTC8304]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKYYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1140818 DQN57_RS04505 WP_111705614.1 863283..864119(+) (dprA) [Streptococcus pyogenes strain NCTC8304]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGTATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTTGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAAGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	43.277	85.612	0.371