Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   DQN40_RS00780 Genome accession   NZ_LS483413
Coordinates   127756..128787 (+) Length   343 a.a.
NCBI ID   WP_084916952.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC7136     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 122756..133787
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN40_RS00770 (NCTC7136_00160) - 126433..126798 (+) 366 WP_003055257.1 DUF1033 family protein -
  DQN40_RS00775 (NCTC7136_00161) comGA/cglA 126879..127820 (+) 942 WP_014611930.1 competence type IV pilus ATPase ComGA Machinery gene
  DQN40_RS00780 (NCTC7136_00162) comYB 127756..128787 (+) 1032 WP_084916952.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQN40_RS00785 (NCTC7136_00163) comYC 128789..129115 (+) 327 WP_084916953.1 competence type IV pilus major pilin ComGC Machinery gene
  DQN40_RS00790 (NCTC7136_00164) comGD 129090..129518 (+) 429 WP_257638821.1 competence type IV pilus minor pilin ComGD -
  DQN40_RS00795 (NCTC7136_00165) comGE 129526..129771 (+) 246 WP_049519695.1 competence type IV pilus minor pilin ComGE -
  DQN40_RS00800 (NCTC7136_00166) comGF 129752..130192 (+) 441 WP_003061780.1 competence type IV pilus minor pilin ComGF -
  DQN40_RS00805 (NCTC7136_00167) comGG 130215..130544 (+) 330 WP_003058539.1 competence type IV pilus minor pilin ComGG -
  DQN40_RS00810 (NCTC7136_00168) comYH 130607..131560 (+) 954 WP_003060701.1 class I SAM-dependent methyltransferase Machinery gene
  DQN40_RS00815 (NCTC7136_00169) - 131619..132815 (+) 1197 WP_084916957.1 acetate kinase -
  DQN40_RS00820 (NCTC7136_00170) - 133123..133329 (+) 207 WP_003058508.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 38965.39 Da        Isoelectric Point: 9.2055

>NTDB_id=1140678 DQN40_RS00780 WP_084916952.1 127756..128787(+) (comYB) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC7136]
MTFLQRDISVRSKQGLKKLSSKEQYKLIQLLANLLLTGFNLAEIIAFLTKSHLIPEPYVLRMEEALLKGRGLADMLAGIG
FSDAILTQISLADGHGNIETTLVNIQGYLNQMAKLKRKTIEVVTYPIILLVFLFVMILGLRHYVMPQLEAQNQLTIFLTH
FPAIFFGIILFIGVLLGGIWLHWRSQSRLKLFIHFSAYPVLGKLLQQYLTAYYAREWGTLIGQGLELPVILDIMAMEKSL
FMQELAEDIRVSLLAGQAFHDKVATYPFFKKELSLMITYGEIKSKLGSELEIYAQESWTQFFSQLHQATQFIQPIIFLVI
ALTIVMIYAAILLPIYQNMGGVL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=1140678 DQN40_RS00780 WP_084916952.1 127756..128787(+) (comYB) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC7136]
ATGACCTTCTTGCAGCGGGACATCTCAGTCCGGAGCAAGCAAGGTTTGAAAAAATTATCCAGTAAGGAACAATACAAACT
AATTCAGCTATTAGCTAACCTTTTGTTAACAGGATTTAACTTGGCTGAGATAATAGCTTTCTTAACAAAAAGTCATTTGA
TTCCCGAGCCCTATGTTCTCCGCATGGAAGAAGCACTCTTAAAAGGTCGAGGGCTGGCAGATATGTTAGCTGGGATAGGT
TTTTCGGATGCTATTTTAACTCAAATTAGTTTAGCAGATGGTCACGGAAACATTGAGACGACGCTTGTTAATATTCAGGG
CTATCTCAACCAAATGGCTAAACTTAAACGAAAAACCATTGAAGTCGTCACCTATCCGATTATTCTCCTGGTATTTCTTT
TTGTGATGATATTAGGGTTAAGGCATTATGTTATGCCTCAATTAGAAGCTCAAAATCAGCTTACTATTTTTCTGACTCAT
TTTCCAGCTATTTTCTTTGGTATTATCCTTTTTATAGGTGTGCTGTTAGGGGGAATTTGGCTGCATTGGCGATCGCAAAG
TCGCCTCAAGCTTTTTATTCACTTCAGTGCTTATCCTGTTTTAGGGAAACTCTTACAACAGTATCTGACGGCTTATTATG
CTAGAGAATGGGGAACATTGATTGGACAGGGACTTGAATTACCAGTCATTCTGGATATTATGGCCATGGAGAAATCTTTA
TTCATGCAAGAATTGGCTGAAGATATTCGAGTTAGTTTATTGGCAGGACAAGCTTTTCATGATAAGGTAGCTACCTATCC
TTTCTTTAAAAAAGAGTTAAGTTTGATGATTACTTATGGAGAGATTAAATCCAAGTTAGGAAGTGAACTAGAGATTTATG
CTCAAGAGAGTTGGACTCAGTTTTTCAGCCAACTTCATCAAGCAACTCAGTTTATTCAACCGATTATCTTTTTAGTGATT
GCTCTGACGATTGTCATGATTTATGCAGCAATTTTATTACCAATTTATCAAAATATGGGAGGCGTTTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(28-146)

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

53.392

98.834

0.528
  comYB Streptococcus mutans UA159

53.392

98.834

0.528
  comYB Streptococcus gordonii str. Challis substr. CH1

48.673

98.834

0.481
  comGB/cglB Streptococcus mitis NCTC 12261

45.97

97.668

0.449
  comGB/cglB Streptococcus mitis SK321

45.345

97.085

0.44
  comGB/cglB Streptococcus pneumoniae Rx1

43.844

97.085

0.426
  comGB/cglB Streptococcus pneumoniae D39

43.844

97.085

0.426
  comGB/cglB Streptococcus pneumoniae R6

43.844

97.085

0.426
  comGB/cglB Streptococcus pneumoniae TIGR4

43.844

97.085

0.426
  comGB Lactococcus lactis subsp. cremoris KW2

42.478

98.834

0.42

Multiple sequence alignment