Detailed information NTG1140674

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: DQN40_RS00350
• Genome accession: NZ_LS483413
• Coordinates: 55510..56421 (+)
• Length: 303 a.a.
• NCBI ID: WP_003060893.1
• Uniprot ID: A0AAE9U6L1
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC7136
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 50510..61421

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN40_RS00325 (NCTC7136_00066)	purE	51011..51499 (+)	489	WP_012766417.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
DQN40_RS00330 (NCTC7136_00067)	purK	51486..52559 (+)	1074	WP_003055561.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
DQN40_RS00335 (NCTC7136_00068)	-	52569..53825 (+)	1257	WP_003055555.1	DUF4041 domain-containing protein	-
DQN40_RS00340 (NCTC7136_00069)	-	53818..54027 (+)	210	WP_014611912.1	hypothetical protein	-
DQN40_RS00345 (NCTC7136_00070)	purB	54076..55368 (+)	1293	WP_003056595.1	adenylosuccinate lyase	-
DQN40_RS00350 (NCTC7136_00071)	comR	55510..56421 (+)	912	WP_003060893.1	XRE family transcriptional regulator	Regulator
DQN40_RS11460 (NCTC7136_00072)	comS	56508..56606 (+)	99	WP_014611913.1	quorum-sensing system DWW-type pheromone	Regulator
DQN40_RS00355 (NCTC7136_00073)	ruvB	56640..57638 (+)	999	WP_015057190.1	Holliday junction branch migration DNA helicase RuvB	-
DQN40_RS00360 (NCTC7136_00074)	-	57773..58204 (+)	432	WP_003059365.1	low molecular weight protein-tyrosine-phosphatase	-
DQN40_RS00365 (NCTC7136_00075)	-	58233..58634 (+)	402	WP_003049089.1	MORN repeat-containing protein	-
DQN40_RS00370 (NCTC7136_00076)	-	58631..60406 (+)	1776	WP_003059359.1	acyltransferase family protein	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35995.62 Da
• Isoelectric Point: 4.7392

>NTDB_id=1140674 DQN40_RS00350 WP_003060893.1 55510..56421(+) (comR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC7136]
MLEHFGEKVRGLRLEKGISREELCGDEAELSVRQLARIELGQSIPSLAKVIFIAKALEVSVGYLTDGANLELPKRYKELK
YLILRTPTYMDDRKLQVRESQFDEIFENYYDQLPEEEKIAIDIIQAKFEVYQTGDINFGFNILKEFLPQLKKKTVYNLNE
LLLIDLYLIILVVSNFTNDLFDEEFYKEITERILEQHQYLLLEDLFLLNNILLSCADTSIRLKMFERLKDTLQLSHFIMS
TIQDFQRMPMYCMYEWKLSIFYLKDIKRAETYFSQSLTFTQMTNDSYLAQKLQKEWDKDIHPS

Nucleotide

• Length: 912 bp

>NTDB_id=1140674 DQN40_RS00350 WP_003060893.1 55510..56421(+) (comR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC7136]
ATGTTAGAGCATTTTGGTGAAAAAGTGAGAGGATTAAGACTTGAGAAAGGGATTAGTCGAGAGGAATTGTGTGGAGATGA
GGCAGAATTGTCTGTTCGCCAGTTGGCGAGGATAGAGCTAGGTCAATCTATACCAAGTTTAGCGAAGGTTATTTTTATTG
CGAAAGCCTTAGAGGTCAGCGTCGGTTATTTGACGGATGGCGCTAACCTAGAACTCCCTAAACGATATAAAGAGTTAAAA
TATCTCATTTTAAGGACTCCGACTTATATGGACGATCGCAAATTACAGGTCCGGGAGTCTCAGTTTGATGAGATATTTGA
AAACTATTATGATCAATTGCCCGAGGAGGAAAAAATAGCGATTGATATTATCCAGGCAAAATTTGAAGTTTATCAGACAG
GTGATATTAATTTTGGTTTTAATATTTTAAAAGAATTTCTACCACAACTAAAAAAGAAAACGGTTTATAACTTAAATGAA
TTATTATTAATTGATTTATATTTAATTATTTTAGTTGTTTCTAACTTTACAAATGACCTATTTGATGAGGAATTTTATAA
AGAAATAACGGAGCGAATCTTAGAACAGCATCAATACCTGTTATTAGAAGATTTATTTCTATTAAATAATATTCTTTTAT
CTTGCGCAGATACTTCTATTCGTTTAAAAATGTTTGAACGACTAAAGGATACGTTACAACTCAGCCATTTTATTATGTCA
ACCATTCAAGATTTTCAGCGAATGCCCATGTATTGCATGTATGAATGGAAATTGTCTATCTTTTATTTAAAAGATATTAA
ACGAGCAGAAACTTATTTTAGTCAATCTCTCACGTTTACTCAAATGACTAATGATAGTTATTTGGCACAAAAGCTTCAAA
AAGAATGGGATAAGGATATTCATCCCTCTTAA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (12-64)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS315	83.389	99.34	0.828
comR	Streptococcus pyogenes MGAS8232	55.629	99.67	0.554
comR	Streptococcus mutans UA159	46.154	98.68	0.455
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	46.575	96.37	0.449
comR	Streptococcus suis P1/7	37.288	97.36	0.363
comR	Streptococcus suis 05ZYH33	37.288	97.36	0.363