Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DQN24_RS03290 Genome accession   NZ_LS483411
Coordinates   652718..653938 (-) Length   406 a.a.
NCBI ID   WP_021035705.1    Uniprot ID   -
Organism   Haemophilus influenzae strain NCTC11426     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 647718..658938
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN24_RS03260 (NCTC11426_00645) - 649185..649391 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DQN24_RS03265 (NCTC11426_00646) - 649465..649671 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DQN24_RS03270 (NCTC11426_00647) cueR 649748..650134 (+) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  DQN24_RS03275 (NCTC11426_00648) metJ 650148..650465 (-) 318 WP_021035707.1 met regulon transcriptional regulator MetJ -
  DQN24_RS03280 (NCTC11426_00649) rho 650713..651975 (+) 1263 WP_005648966.1 transcription termination factor Rho -
  DQN24_RS03285 (NCTC11426_00650) pilD 652029..652721 (-) 693 WP_041175383.1 prepilin peptidase Machinery gene
  DQN24_RS03290 (NCTC11426_00651) pilC 652718..653938 (-) 1221 WP_021035705.1 type II secretion system F family protein Machinery gene
  DQN24_RS03295 (NCTC11426_00652) pilB 653935..655329 (-) 1395 WP_111695393.1 GspE/PulE family protein Machinery gene
  DQN24_RS03300 (NCTC11426_00653) pilA 655326..655775 (-) 450 WP_021035703.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  DQN24_RS03305 (NCTC11426_00654) ampD 655890..656444 (+) 555 WP_021035702.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  DQN24_RS03310 (NCTC11426_00655) corC 657076..657975 (+) 900 WP_021035700.1 CNNM family magnesium/cobalt transport protein CorC -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46331.46 Da        Isoelectric Point: 9.7232

>NTDB_id=1140663 DQN24_RS03290 WP_021035705.1 652718..653938(-) (pilC) [Haemophilus influenzae strain NCTC11426]
MTKKLFYYQASNALNQEQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLSVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFAFSFFLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDMVLDKEVRSILQWVSQG
YAFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDFLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=1140663 DQN24_RS03290 WP_021035705.1 652718..653938(-) (pilC) [Haemophilus influenzae strain NCTC11426]
ATGACTAAAAAACTCTTTTATTATCAAGCTAGTAACGCATTAAATCAGGAACAAAAAGGCTCAATTATTGCGGATACAAA
ACAACAAGCACACTTTCAATTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATTAGTGAATTACTCAATCAATTAGCCACGTTGCTACAGTCCGCTATTCCGTTAAAAAACAGTCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAATGAATGGCTTGAACGACTACTTCAATCTATTGAATCTGGTTT
AGCATTCTCACAAGCCATTGAACAACAAGGGAAATATCTTACTCAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CGGGAAAACTTTCCGTTGTTTGTAAAAAAATAGCCACGCATCGTAGCCAATCTTTAGCATTGCAACGTAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCTGAGTTACCAACAATAACCGCAATATTGCTCTCAATATCTAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTTAGTTTTTTTCTATTTTATTACTTCTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAGCTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAGGCTGGCGTACCGCTTAATCAGGCACTAGACAGTTTTCTTCCTCGCACACAAACTT
GGCAAACCAAGAAAACGCTTGTAAACGATATGGTATTAGATAAAGAAGTGCGGTCAATTTTGCAATGGGTTTCTCAAGGC
TATGCGTTTTCTAATAGCGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTACAAATTGGCGAGCAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATCGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTCCTCTCACAAA
TGCTAGAACCATTAATGATGGTAATCATCGGAAGCCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGTTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.783

100

0.978
  pilC Haemophilus influenzae Rd KW20

97.537

100

0.975
  pilC Glaesserella parasuis strain SC1401

37.905

98.768

0.374

Multiple sequence alignment