Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   DQN24_RS03285 Genome accession   NZ_LS483411
Coordinates   652029..652721 (-) Length   230 a.a.
NCBI ID   WP_041175383.1    Uniprot ID   -
Organism   Haemophilus influenzae strain NCTC11426     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 647029..657721
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN24_RS03255 (NCTC11426_00644) - 647042..649210 (-) 2169 WP_041175384.1 heavy metal translocating P-type ATPase -
  DQN24_RS03260 (NCTC11426_00645) - 649185..649391 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DQN24_RS03265 (NCTC11426_00646) - 649465..649671 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DQN24_RS03270 (NCTC11426_00647) cueR 649748..650134 (+) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  DQN24_RS03275 (NCTC11426_00648) metJ 650148..650465 (-) 318 WP_021035707.1 met regulon transcriptional regulator MetJ -
  DQN24_RS03280 (NCTC11426_00649) rho 650713..651975 (+) 1263 WP_005648966.1 transcription termination factor Rho -
  DQN24_RS03285 (NCTC11426_00650) pilD 652029..652721 (-) 693 WP_041175383.1 prepilin peptidase Machinery gene
  DQN24_RS03290 (NCTC11426_00651) pilC 652718..653938 (-) 1221 WP_021035705.1 type II secretion system F family protein Machinery gene
  DQN24_RS03295 (NCTC11426_00652) pilB 653935..655329 (-) 1395 WP_111695393.1 GspE/PulE family protein Machinery gene
  DQN24_RS03300 (NCTC11426_00653) pilA 655326..655775 (-) 450 WP_021035703.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  DQN24_RS03305 (NCTC11426_00654) ampD 655890..656444 (+) 555 WP_021035702.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26754.82 Da        Isoelectric Point: 9.1329

>NTDB_id=1140662 DQN24_RS03285 WP_041175383.1 652029..652721(-) (pilD) [Haemophilus influenzae strain NCTC11426]
MIYFIMFLLGGILGIALWFYLSGFITHLQQEIYATYVELFPQNRSPFQPHFASIQQKKCGHILRYFLSVGVGFIFLQIAF
KDSIFTVWIGLTLIILWTISYLDWHYQLISTTPCLWLLTLGLFGADNNFSLLTLSESIKSAASFFIVFYAIYWIAKCYYR
KEAFGRGDYWLAMALGSFIRLETLPHFLLLASVLGICFSLIHKKKKEFIPFAPFMNLSAVIIYFVKYYGY

Nucleotide


Download         Length: 693 bp        

>NTDB_id=1140662 DQN24_RS03285 WP_041175383.1 652029..652721(-) (pilD) [Haemophilus influenzae strain NCTC11426]
ATGATTTATTTCATAATGTTTTTATTAGGCGGTATCTTAGGGATCGCATTGTGGTTCTACCTATCTGGTTTTATTACGCA
TTTGCAGCAAGAGATTTATGCGACTTACGTTGAATTATTTCCACAAAACCGTTCTCCATTTCAACCGCACTTTGCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGGTATTTTTTAAGTGTTGGAGTTGGATTTATATTTTTACAAATTGCCTTC
AAAGATTCTATTTTTACTGTATGGATCGGACTCACACTTATTATTCTTTGGACAATCAGTTATCTTGATTGGCACTATCA
ACTTATTTCTACGACACCCTGTTTATGGTTACTTACTCTAGGATTATTTGGAGCAGACAATAACTTTTCATTGCTAACGT
TATCTGAAAGCATAAAAAGTGCGGCTAGTTTTTTTATTGTTTTCTACGCAATCTATTGGATTGCAAAATGTTATTACAGA
AAAGAAGCCTTTGGACGGGGAGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCGTTTAGAAACCTTACCGCACTT
TTTATTATTAGCCTCAGTGCTTGGAATATGTTTTTCGCTTATTCATAAAAAGAAAAAAGAATTTATACCTTTTGCCCCTT
TTATGAACTTATCAGCTGTCATCATTTATTTCGTCAAATATTACGGATATTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(92-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae 86-028NP

96.957

100

0.97
  pilD Haemophilus influenzae Rd KW20

94.348

100

0.943

Multiple sequence alignment