Detailed information NTG1140596

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: DQN21_RS12505
• Genome accession: NZ_LS483409
• Coordinates: 2491267..2492532 (+)
• Length: 421 a.a.
• NCBI ID: WP_077497985.1
• Uniprot ID: -
• Organism: Streptococcus gallolyticus strain NCTC13773
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2486267..2497532

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN21_RS12480 (NCTC13773_02536)	-	2487230..2489824 (+)	2595	WP_077497984.1	YfhO family protein	-
DQN21_RS12500 (NCTC13773_02540)	rlmH	2490577..2491056 (-)	480	WP_009855220.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
DQN21_RS12505 (NCTC13773_02541)	htrA	2491267..2492532 (+)	1266	WP_077497985.1	S1C family serine protease	Regulator
DQN21_RS12510 (NCTC13773_02542)	spo0J	2492602..2493378 (+)	777	WP_074658518.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 421 a.a.
• Molecular weight: 43818.56 Da
• Isoelectric Point: 4.0575

>NTDB_id=1140596 DQN21_RS12505 WP_077497985.1 2491267..2492532(+) (htrA) [Streptococcus gallolyticus strain NCTC13773]
MKKIKLPNLPKLPKFNYKNWLKPLGVILVGFIAGIAGTILVLNMAGISITNVSGSSTKTTTSSVSYSNSNDTTKAVEKVQ
DAVVSVINYKSDSSSSTSDLYNQMFGNDSDSSSDSSSTDDLTVYSEGSGVIYKKDGDSAYVVTNNHVIDGAEQIEIMLAD
GTKVVGELVGADTYSDIAVVKISSDNVSTVAEFADSDKLTVGETAIAIGSPLGTEYANSVTQGIVSSLSRTVTMTNDDGE
TISTNAIQTDAAINPGNSGGALINIEGQVIGINSSKISSTSSSGESVEGMGFAIPSNDVVSIINQLEENGQVIRPALGIS
MVNLSDLSTNAIAQLNIPTSVTSGVVVAAVQSGMPAEGNLEQYDVITAIDDQEVTSTSDLQSILYTHSVGDSVKVTFYRG
TDKKTATIELTKTTQDLSSSN

Nucleotide

• Length: 1266 bp

>NTDB_id=1140596 DQN21_RS12505 WP_077497985.1 2491267..2492532(+) (htrA) [Streptococcus gallolyticus strain NCTC13773]
GTGAAAAAAATAAAATTACCAAATTTACCCAAGTTGCCAAAATTTAATTACAAAAATTGGTTAAAACCATTGGGTGTCAT
TTTAGTCGGCTTTATAGCTGGTATCGCAGGTACAATACTCGTCCTAAATATGGCAGGTATTTCAATCACTAACGTCAGTG
GTTCAAGTACAAAAACAACAACAAGTAGCGTAAGCTATTCTAACTCTAACGATACAACAAAAGCTGTGGAAAAAGTTCAA
GACGCAGTTGTATCTGTTATTAACTACAAATCAGACTCGTCGTCTTCTACAAGTGACCTCTACAATCAAATGTTTGGCAA
TGATTCAGACAGTAGTAGCGATTCAAGCTCTACAGATGATTTGACTGTTTACAGTGAAGGTTCTGGGGTTATTTACAAAA
AAGATGGTGATTCTGCTTATGTCGTCACTAACAATCACGTTATTGATGGGGCCGAACAAATTGAAATCATGCTTGCTGAT
GGAACAAAAGTTGTTGGTGAGCTAGTCGGAGCAGATACTTATTCAGATATTGCCGTTGTCAAAATTTCTTCTGACAACGT
ATCTACAGTTGCTGAATTTGCCGATTCTGATAAATTGACTGTCGGTGAAACTGCTATCGCTATTGGTAGCCCACTTGGTA
CTGAATATGCTAACTCTGTAACACAAGGTATTGTCTCAAGTCTTAGCCGTACAGTAACCATGACAAATGATGATGGTGAA
ACTATCTCAACAAATGCTATCCAAACGGATGCAGCGATTAACCCAGGTAACTCTGGTGGTGCTTTAATTAACATTGAAGG
ACAAGTTATCGGTATCAATTCAAGTAAGATTTCATCTACATCAAGTTCTGGTGAATCTGTCGAAGGTATGGGATTTGCCA
TTCCATCTAACGATGTTGTATCCATTATTAACCAATTGGAAGAAAATGGGCAAGTTATCCGTCCAGCACTTGGTATTTCA
ATGGTAAACTTGAGCGACCTTTCAACAAATGCAATTGCTCAACTTAACATTCCAACAAGTGTAACAAGCGGTGTCGTTGT
GGCGGCTGTTCAATCTGGTATGCCAGCTGAAGGTAATCTCGAACAATATGATGTCATCACAGCTATTGACGACCAAGAAG
TAACATCTACTTCAGATCTTCAAAGTATCCTTTATACTCATTCTGTTGGTGACTCTGTCAAAGTAACCTTCTACCGTGGA
ACTGATAAGAAAACAGCCACAATTGAATTAACTAAGACAACACAAGATTTATCTTCCTCAAACTGA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (127-272)

• PDZ domain (PDZ_2) (315-410)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	64.444	96.2	0.62
htrA	Streptococcus gordonii str. Challis substr. CH1	59.804	96.912	0.58
htrA	Streptococcus pneumoniae D39	57.908	97.625	0.565
htrA	Streptococcus pneumoniae TIGR4	57.908	97.625	0.565
htrA	Streptococcus mitis NCTC 12261	57.908	97.625	0.565
htrA	Streptococcus pneumoniae R6	57.908	97.625	0.565
htrA	Streptococcus pneumoniae Rx1	57.908	97.625	0.565