Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   DQN33_RS10090 Genome accession   NZ_LS483408
Coordinates   2021981..2023177 (+) Length   398 a.a.
NCBI ID   WP_172455898.1    Uniprot ID   -
Organism   Streptococcus uberis strain NCTC4674     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2016981..2028177
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN33_RS10065 (NCTC4674_02119) - 2018204..2020774 (+) 2571 WP_046389799.1 YfhO family protein -
  DQN33_RS10085 (NCTC4674_02123) rlmH 2021310..2021789 (-) 480 WP_046389780.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  DQN33_RS10090 (NCTC4674_02124) htrA 2021981..2023177 (+) 1197 WP_172455898.1 S1C family serine protease Regulator
  DQN33_RS10095 (NCTC4674_02125) spo0J 2023255..2024031 (+) 777 WP_111673597.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 398 a.a.        Molecular weight: 42377.88 Da        Isoelectric Point: 5.1117

>NTDB_id=1140530 DQN33_RS10090 WP_172455898.1 2021981..2023177(+) (htrA) [Streptococcus uberis strain NCTC4674]
MSKFKHFFKYIMIVGLGFIGGALAFFVMNLLPHPSSTTNLNNPTTTSKVTYKNTTNTTKAVKVIQDAVVSVVNYQKNDSL
NSAMDIFSQGDSSTKENDGLSIYSEGSGVIYKKDGDSAYLVTNNHVIDKAERIEIILADGSKVVGKLIGADTYSDLAVVK
ISSDKIKTVAQFADSSKINIGEVAIAIGSPLGTEYANSVTEGIVSSLSRTVTLKNEEGQTVSTNAIQTDAAINPGNSGGP
LINIEGQIIGINSSKISQSKSSGNTVEGMGFAIPANDVIKIINQLESKGEVVRPALGISMVNLSDLSTNALDQLKVPKNV
TSGIVVAKVVDNMPASGKLEQYDIITEIDGEEVSSTSDLQSILYGHDINDTVKVTFYRGNDKKSTTIELTKTTKDLEK

Nucleotide


Download         Length: 1197 bp        

>NTDB_id=1140530 DQN33_RS10090 WP_172455898.1 2021981..2023177(+) (htrA) [Streptococcus uberis strain NCTC4674]
GTGTCTAAGTTTAAACATTTTTTCAAATACATAATGATAGTCGGATTAGGCTTCATTGGTGGTGCTTTAGCATTCTTTGT
GATGAATCTGTTACCACATCCATCATCCACAACAAATCTTAATAACCCAACGACGACAAGTAAAGTAACCTATAAAAATA
CTACTAATACGACTAAAGCTGTTAAAGTGATTCAAGATGCTGTTGTTTCTGTAGTTAACTATCAAAAAAATGATTCTTTA
AACTCAGCCATGGATATTTTTAGTCAAGGTGATTCATCAACTAAAGAGAATGATGGACTTTCTATTTATAGTGAGGGATC
AGGTGTTATATACAAAAAAGATGGTGATTCTGCATATCTGGTAACCAACAACCACGTAATAGACAAAGCTGAAAGAATTG
AAATTATTTTAGCTGATGGTTCAAAAGTTGTTGGGAAATTAATTGGTGCTGACACTTATTCTGACTTGGCTGTTGTAAAA
ATTTCTTCAGACAAAATTAAGACTGTAGCTCAGTTTGCAGATTCTTCCAAAATAAACATAGGTGAAGTTGCAATTGCAAT
TGGTAGTCCTCTTGGAACAGAATATGCTAATTCCGTAACTGAAGGAATTGTTTCAAGTTTAAGTAGAACAGTAACTTTAA
AAAATGAAGAAGGACAAACTGTTTCAACTAATGCCATTCAAACAGATGCTGCTATTAACCCTGGAAACTCTGGCGGACCT
TTAATTAATATTGAAGGACAAATTATTGGAATAAACTCTAGCAAAATCTCACAGTCTAAATCATCTGGAAATACAGTCGA
AGGAATGGGATTTGCAATTCCAGCTAATGACGTTATTAAAATTATTAACCAACTTGAAAGCAAAGGCGAAGTAGTTCGAC
CTGCATTAGGTATTTCAATGGTTAATCTAAGTGATTTATCAACAAATGCCCTTGATCAGCTCAAAGTTCCAAAAAATGTT
ACTAGTGGTATCGTAGTTGCTAAAGTCGTAGACAATATGCCTGCCTCAGGAAAACTTGAACAATATGATATTATCACTGA
AATTGATGGGGAAGAGGTGAGCAGTACAAGTGATTTACAAAGTATTCTGTATGGGCATGACATTAATGATACCGTAAAAG
TCACTTTTTATAGAGGTAATGATAAGAAATCTACTACTATTGAATTAACTAAAACTACCAAAGATTTAGAAAAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(294-389)

Trypsin-like peptidase domain (Trypsin_2)

(106-251)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

62.785

99.246

0.623
  htrA Streptococcus pneumoniae Rx1

56.091

98.995

0.555
  htrA Streptococcus pneumoniae D39

56.091

98.995

0.555
  htrA Streptococcus gordonii str. Challis substr. CH1

56.091

98.995

0.555
  htrA Streptococcus pneumoniae R6

56.091

98.995

0.555
  htrA Streptococcus pneumoniae TIGR4

56.091

98.995

0.555
  htrA Streptococcus mitis NCTC 12261

55.838

98.995

0.553

Multiple sequence alignment