Detailed information NTG1140319

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: DQN23_RS00355
• Genome accession: NZ_LS483403
• Coordinates: 51353..52231 (+)
• Length: 292 a.a.
• NCBI ID: WP_171009918.1
• Uniprot ID: -
• Organism: Streptococcus lutetiensis strain NCTC13774
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 46353..57231

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN23_RS00325 (NCTC13774_00065)	purD	46413..47675 (+)	1263	WP_111712548.1	phosphoribosylamine--glycine ligase	-
DQN23_RS00330 (NCTC13774_00066)	-	47665..48114 (+)	450	WP_111712549.1	DUF523 domain-containing protein	-
DQN23_RS00335 (NCTC13774_00067)	purE	48114..48602 (+)	489	WP_058813548.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
DQN23_RS00340 (NCTC13774_00068)	purK	48589..49680 (+)	1092	WP_111698145.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
DQN23_RS09160	-	49683..49778 (+)	96	Protein_33	phosphoribosylaminoimidazole carboxylase	-
DQN23_RS00350 (NCTC13774_00069)	purB	49868..51166 (+)	1299	WP_058813549.1	adenylosuccinate lyase	-
DQN23_RS00355 (NCTC13774_00070)	comR	51353..52231 (+)	879	WP_171009918.1	Cro/Cl family transcriptional regulator	Regulator
DQN23_RS00360 (NCTC13774_00071)	ruvB	52433..53431 (+)	999	WP_020916203.1	Holliday junction branch migration DNA helicase RuvB	-
DQN23_RS09125 (NCTC13774_00072)	-	53604..53810 (+)	207	WP_197712753.1	DUF7010 family protein	-
DQN23_RS09625 (NCTC13774_00073)	-	53770..54135 (+)	366	WP_231853261.1	DUF7010 family protein	-
DQN23_RS00370 (NCTC13774_00074)	-	54374..54805 (+)	432	WP_014334179.1	low molecular weight protein-tyrosine-phosphatase	-
DQN23_RS00375 (NCTC13774_00075)	-	54823..55203 (+)	381	WP_006531314.1	membrane protein	-
DQN23_RS00380 (NCTC13774_00076)	-	55200..56993 (+)	1794	WP_111712551.1	acyltransferase family protein	-

Sequence

Protein

• Length: 292 a.a.
• Molecular weight: 34529.34 Da
• Isoelectric Point: 4.6432

>NTDB_id=1140319 DQN23_RS00355 WP_171009918.1 51353..52231(+) (comR) [Streptococcus lutetiensis strain NCTC13774]
MREEKEISREEFYGDETELSVRQLARIELNQSIPNLSKASFIANRLGVKLGTLTDGDSLELPKRYKELKYLLLRTPTYGD
QVRLDRKNDYFDEIAEVFYDVIPEEERLIIDCLQSKFDVHFSEDVNFGEGILNDYFGQVNRKKVFTINDLILIDLYFACL
SSAKKFEGIYSLNFYDDLMKRLVNQKHVSPETDLILNNVLLNNIDLAFQFKREYYIERVITISEKIMTEIHDFQRRPILS
LVEWKYYLKFKHDFALAEQSFTNATLFARLVGDTYLENKLKEEWQLDIDAVE

Nucleotide

• Length: 879 bp

>NTDB_id=1140319 DQN23_RS00355 WP_171009918.1 51353..52231(+) (comR) [Streptococcus lutetiensis strain NCTC13774]
ATGCGGGAGGAAAAGGAAATCTCACGTGAAGAATTCTATGGGGATGAAACAGAATTATCGGTAAGACAATTAGCTAGAAT
TGAGTTGAACCAATCAATACCCAATCTCAGTAAAGCAAGCTTTATTGCCAATCGTCTGGGAGTGAAATTAGGTACCTTAA
CTGATGGTGACAGTTTAGAATTACCTAAGCGGTATAAAGAGTTGAAGTATTTACTTCTTCGAACACCTACATATGGAGAC
CAGGTACGACTTGATCGAAAAAATGACTATTTTGATGAGATTGCTGAAGTATTTTATGATGTTATTCCAGAAGAAGAACG
GTTAATCATTGATTGTTTACAATCAAAATTCGATGTTCATTTTAGTGAAGATGTCAATTTTGGAGAGGGTATTTTAAATG
ATTATTTTGGTCAAGTTAATCGAAAGAAAGTTTTTACCATTAATGATTTAATTTTGATTGATCTTTACTTTGCTTGTCTT
TCTTCTGCTAAGAAGTTTGAAGGAATTTATAGTTTGAATTTTTACGATGATTTGATGAAAAGGTTGGTAAATCAAAAGCA
TGTTTCACCTGAGACTGATTTAATTTTAAATAATGTATTGTTAAATAATATTGACTTAGCATTCCAATTTAAACGAGAAT
ATTATATTGAGCGTGTTATTACAATCAGTGAAAAAATTATGACAGAGATTCATGATTTTCAACGTCGTCCGATTTTAAGT
TTGGTGGAGTGGAAGTATTATCTGAAATTTAAACATGACTTTGCTTTAGCAGAACAGTCATTTACGAATGCAACATTATT
TGCACGATTGGTTGGTGATACTTATTTAGAAAATAAACTTAAAGAAGAATGGCAACTTGATATTGATGCTGTGGAGTAG

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (62-284)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	98.973	100	0.99
comR	Streptococcus mutans UA159	52.778	98.63	0.521
comR	Streptococcus pyogenes MGAS8232	51.027	100	0.51
comR	Streptococcus pyogenes MGAS315	45.548	100	0.455
comR	Streptococcus suis D9	36.519	100	0.366
comR	Streptococcus suis P1/7	36.806	98.63	0.363
comR	Streptococcus suis 05ZYH33	36.806	98.63	0.363