Detailed information NTG1140291

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQM79_RS04795
• Genome accession: NZ_LS483401
• Coordinates: 915882..916718 (+)
• Length: 278 a.a.
• NCBI ID: WP_002989770.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC10085
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 910882..921718

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM79_RS04765 (NCTC10085_00933)	-	911364..911804 (+)	441	WP_024623381.1	hypothetical protein	-
DQM79_RS04770 (NCTC10085_00934)	-	911854..912765 (-)	912	WP_002989777.1	diacylglycerol/lipid kinase family protein	-
DQM79_RS04775 (NCTC10085_00935)	trhA	912882..913532 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DQM79_RS04780 (NCTC10085_00936)	-	913529..913969 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
DQM79_RS04785 (NCTC10085_00937)	ylqF	914188..915036 (+)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
DQM79_RS04790 (NCTC10085_00938)	-	915026..915817 (+)	792	WP_002989771.1	ribonuclease HII	-
DQM79_RS04795 (NCTC10085_00939)	dprA	915882..916718 (+)	837	WP_002989770.1	DNA-processing protein DprA	Machinery gene
DQM79_RS04800 (NCTC10085_00940)	topA	916825..918954 (+)	2130	WP_002989768.1	type I DNA topoisomerase	-
DQM79_RS09150	-	919029..919886 (-)	858	Protein_877	LysR family transcriptional regulator	-
DQM79_RS04815 (NCTC10085_00942)	-	919926..920492 (+)	567	Protein_878	PTS sugar transporter subunit IIC	-
DQM79_RS04820 (NCTC10085_00943)	-	920507..921499 (+)	993	WP_002989762.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30956.84 Da
• Isoelectric Point: 8.5841

>NTDB_id=1140291 DQM79_RS04795 WP_002989770.1 915882..916718(+) (dprA) [Streptococcus pyogenes strain NCTC10085]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1140291 DQM79_RS04795 WP_002989770.1 915882..916718(+) (dprA) [Streptococcus pyogenes strain NCTC10085]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATAGAATTTAAACAGTTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367