Detailed information NTG1140096

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQM37_RS04465
• Genome accession: NZ_LS483394
• Coordinates: 866058..866894 (+)
• Length: 278 a.a.
• NCBI ID: WP_076639652.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC10880
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 861058..871894

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM37_RS04435 (NCTC10880_00883)	-	861540..861980 (+)	441	WP_024623381.1	hypothetical protein	-
DQM37_RS04440 (NCTC10880_00884)	-	862030..862941 (-)	912	WP_002989777.1	diacylglycerol/lipid kinase family protein	-
DQM37_RS04445 (NCTC10880_00885)	trhA	863058..863708 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DQM37_RS04450 (NCTC10880_00886)	-	863705..864145 (-)	441	WP_111694807.1	DUF1836 domain-containing protein	-
DQM37_RS04455 (NCTC10880_00887)	ylqF	864364..865212 (+)	849	WP_111694808.1	ribosome biogenesis GTPase YlqF	-
DQM37_RS04460 (NCTC10880_00888)	-	865202..865993 (+)	792	WP_111694809.1	ribonuclease HII	-
DQM37_RS04465 (NCTC10880_00889)	dprA	866058..866894 (+)	837	WP_076639652.1	DNA-processing protein DprA	Machinery gene
DQM37_RS04470 (NCTC10880_00890)	topA	867001..869130 (+)	2130	WP_111694810.1	type I DNA topoisomerase	-
DQM37_RS09075	-	869205..870089 (-)	885	Protein_813	LysR family transcriptional regulator	-
DQM37_RS04485 (NCTC10880_00892)	-	870102..870668 (+)	567	Protein_814	PTS sugar transporter subunit IIC	-
DQM37_RS04490 (NCTC10880_00893)	-	870683..871675 (+)	993	WP_111694811.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30978.99 Da
• Isoelectric Point: 9.2511

>NTDB_id=1140096 DQM37_RS04465 WP_076639652.1 866058..866894(+) (dprA) [Streptococcus pyogenes strain NCTC10880]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1140096 DQM37_RS04465 WP_076639652.1 866058..866894(+) (dprA) [Streptococcus pyogenes strain NCTC10880]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGATAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363