Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   DQM45_RS06940 Genome accession   NZ_LS483388
Coordinates   1401591..1402301 (-) Length   236 a.a.
NCBI ID   WP_003084933.1    Uniprot ID   -
Organism   Streptococcus porcinus strain NCTC10999     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1396591..1407301
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM45_RS06925 (NCTC10999_01411) rnc 1398630..1399322 (-) 693 WP_003085736.1 ribonuclease III -
  DQM45_RS06930 (NCTC10999_01412) vicX 1399427..1400239 (-) 813 WP_003084363.1 MBL fold metallo-hydrolase Regulator
  DQM45_RS06935 (NCTC10999_01413) vicK 1400240..1401598 (-) 1359 WP_003082933.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQM45_RS06940 (NCTC10999_01414) vicR 1401591..1402301 (-) 711 WP_003084933.1 response regulator YycF Regulator
  DQM45_RS06945 (NCTC10999_01415) - 1402562..1403341 (+) 780 WP_003083323.1 amino acid ABC transporter ATP-binding protein -
  DQM45_RS06950 (NCTC10999_01416) - 1403354..1404172 (+) 819 WP_003083506.1 transporter substrate-binding domain-containing protein -
  DQM45_RS06955 (NCTC10999_01417) - 1404190..1404894 (+) 705 WP_003085779.1 amino acid ABC transporter permease -
  DQM45_RS06960 (NCTC10999_01418) - 1404910..1405557 (+) 648 WP_003084630.1 amino acid ABC transporter permease -
  DQM45_RS06965 (NCTC10999_01419) - 1405609..1406634 (-) 1026 WP_003084434.1 DUF3114 domain-containing protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27172.12 Da        Isoelectric Point: 4.9981

>NTDB_id=1139803 DQM45_RS06940 WP_003084933.1 1401591..1402301(-) (vicR) [Streptococcus porcinus strain NCTC10999]
MKKILIVDDEKPISDIIKFNLTKEGYDIMTAFDGREAITIFEEDKPDLVILDLMLPEMDGLEVAKEIRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGNQELTIGNLQILPDAFLAKKYGKEVE
LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKQHD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1139803 DQM45_RS06940 WP_003084933.1 1401591..1402301(-) (vicR) [Streptococcus porcinus strain NCTC10999]
ATGAAAAAAATCCTCATTGTAGACGATGAAAAACCTATTTCAGATATTATAAAGTTTAATTTGACCAAAGAAGGTTATGA
TATTATGACGGCTTTTGATGGCCGAGAAGCCATTACAATCTTCGAAGAAGATAAACCTGACTTGGTTATTTTGGATTTAA
TGTTACCAGAGATGGATGGTCTTGAAGTCGCAAAAGAAATCCGAAAAACCAGTCATATCCCTATTATCATGCTTTCTGCA
AAAGATAGTGAATTTGATAAGGTGATTGGTTTAGAAATCGGTGCGGATGATTACGTGACAAAACCTTTTTCAAATCGTGA
GCTCCTAGCGCGTGTTAAAGCTCATTTGCGACGTACTGAGACGATTGAAACAGCTGTTGCTGAAGAAAATGCTTCTTCAG
GAAATCAAGAATTAACTATCGGTAATCTCCAGATTCTACCAGATGCTTTCTTGGCTAAAAAATATGGCAAAGAAGTTGAA
CTGACACATCGCGAATTTGAATTATTACATCATTTAGCAAATCATATTGGGCAAGTTATGACCCGTGAACATTTATTAGA
AACCGTCTGGGGCTATGATTATTTTGGTGATGTGAGAACTGTTGATGTTACCGTACGACGTTTGAGAGAAAAAATAGAAG
ACACACCAAGCCGTCCTGAATATATTTTGACAAGACGTGGCGTTGGTTATTATATGAAACAGCATGACTAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

87.712

100

0.877
  micA Streptococcus pneumoniae Cp1015

77.447

99.576

0.771
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.777

98.729

0.432
  covR Streptococcus salivarius strain HSISS4

42.735

99.153

0.424
  scnR Streptococcus mutans UA159

37.768

98.729

0.373

Multiple sequence alignment