Detailed information NTG1139699

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQM82_RS04770
• Genome accession: NZ_LS483386
• Coordinates: 911679..912515 (+)
• Length: 278 a.a.
• NCBI ID: WP_023611998.1
• Uniprot ID: A0A5S4TFX7
• Organism: Streptococcus pyogenes strain NCTC13742
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 906679..917515

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM82_RS04740 (NCTC13742_00935)	-	907233..907601 (+)	369	WP_010922310.1	hypothetical protein	-
DQM82_RS04745 (NCTC13742_00936)	-	907651..908562 (-)	912	WP_023612012.1	diacylglycerol/lipid kinase family protein	-
DQM82_RS04750 (NCTC13742_00937)	trhA	908679..909329 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DQM82_RS04755 (NCTC13742_00938)	-	909326..909766 (-)	441	WP_011017769.1	DUF1836 domain-containing protein	-
DQM82_RS04760 (NCTC13742_00939)	ylqF	909985..910833 (+)	849	WP_023611994.1	ribosome biogenesis GTPase YlqF	-
DQM82_RS04765 (NCTC13742_00940)	-	910823..911614 (+)	792	WP_023612045.1	ribonuclease HII	-
DQM82_RS04770 (NCTC13742_00941)	dprA	911679..912515 (+)	837	WP_023611998.1	DNA-processing protein DprA	Machinery gene
DQM82_RS04775 (NCTC13742_00942)	topA	912623..914752 (+)	2130	WP_050336211.1	type I DNA topoisomerase	-
DQM82_RS09920	-	914827..915711 (-)	885	Protein_874	LysR family transcriptional regulator	-
DQM82_RS04790 (NCTC13742_00944)	-	915724..916290 (+)	567	Protein_875	PTS sugar transporter subunit IIC	-
DQM82_RS04795 (NCTC13742_00945)	-	916305..917297 (+)	993	WP_023612447.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30958.92 Da
• Isoelectric Point: 8.8230

>NTDB_id=1139699 DQM82_RS04770 WP_023611998.1 911679..912515(+) (dprA) [Streptococcus pyogenes strain NCTC13742]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGAACVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1139699 DQM82_RS04770 WP_023611998.1 911679..912515(+) (dprA) [Streptococcus pyogenes strain NCTC13742]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCTGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACTGGAGTAAAGTCTGTCCGTAAAATTCTCAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAGCATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

3D structure

• AlphaFold DB: A0A5S4TFX7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367