Detailed information NTG1139455

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQM89_RS05070
• Genome accession: NZ_LS483382
• Coordinates: 949979..950815 (+)
• Length: 278 a.a.
• NCBI ID: WP_023079425.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC13738
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 944979..955815

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM89_RS05040 (NCTC13738_01002)	-	945467..945901 (+)	435	WP_023079442.1	hypothetical protein	-
DQM89_RS05045 (NCTC13738_01003)	-	945951..946862 (-)	912	WP_076634236.1	diacylglycerol/lipid kinase family protein	-
DQM89_RS05050 (NCTC13738_01004)	trhA	946979..947629 (-)	651	WP_076634237.1	PAQR family membrane homeostasis protein TrhA	-
DQM89_RS05055 (NCTC13738_01005)	-	947626..948066 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
DQM89_RS05060 (NCTC13738_01006)	ylqF	948285..949133 (+)	849	WP_076634238.1	ribosome biogenesis GTPase YlqF	-
DQM89_RS05065 (NCTC13738_01007)	-	949123..949914 (+)	792	WP_023610685.1	ribonuclease HII	-
DQM89_RS05070 (NCTC13738_01008)	dprA	949979..950815 (+)	837	WP_023079425.1	DNA-processing protein DprA	Machinery gene
DQM89_RS05075 (NCTC13738_01009)	topA	950923..953052 (+)	2130	WP_011017773.1	type I DNA topoisomerase	-
DQM89_RS09575	-	953127..954011 (-)	885	Protein_933	LysR family transcriptional regulator	-
DQM89_RS05090 (NCTC13738_01011)	-	954024..954577 (+)	554	Protein_934	PTS sugar transporter subunit IIC	-
DQM89_RS05095 (NCTC13738_01012)	-	954592..955584 (+)	993	WP_076634239.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31046.98 Da
• Isoelectric Point: 8.5827

>NTDB_id=1139455 DQM89_RS05070 WP_023079425.1 949979..950815(+) (dprA) [Streptococcus pyogenes strain NCTC13738]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEDR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1139455 DQM89_RS05070 WP_023079425.1 949979..950815(+) (dprA) [Streptococcus pyogenes strain NCTC13738]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCTGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACTGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGACCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367