Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   DQM69_RS08975 Genome accession   NZ_LS483381
Coordinates   1842139..1844445 (-) Length   768 a.a.
NCBI ID   WP_032672998.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain NCTC10921     
Function   transport of ComC (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1840051..1846130 1842139..1844445 within 0


Gene organization within MGE regions


Location: 1840051..1846130
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM69_RS08965 (NCTC10921_01785) - 1840051..1841040 (-) 990 WP_111687998.1 IS30 family transposase -
  DQM69_RS08970 (NCTC10921_01786) comB/nlmE 1841202..1842125 (-) 924 WP_109982751.1 HlyD family efflux transporter periplasmic adaptor subunit Regulator
  DQM69_RS08975 (NCTC10921_01787) comA/nlmT 1842139..1844445 (-) 2307 WP_032672998.1 peptide cleavage/export ABC transporter Regulator
  DQM69_RS08980 - 1844974..1846130 (-) 1157 Protein_1700 IS256 family transposase -

Sequence

Protein


Download         Length: 768 a.a.        Molecular weight: 85991.78 Da        Isoelectric Point: 8.2453

>NTDB_id=1139414 DQM69_RS08975 WP_032672998.1 1842139..1844445(-) (comA/nlmT) [Streptococcus sobrinus strain NCTC10921]
MKQITYIILIVALVIAVNIILEAFRRYFRSKRGKSSPQSSQAVAGSSSSVGLFWRRRYKFIPQVDTRDCGPAALASVAKH
YGSDYSLARLRELSKTDKQGTTALGLVEAAKAIGFETRSIKADMTLFDYTDLTYPFIVHVVKNKRLQHYYVVYGNDKNNL
IIGDPDPNVKVTRMSKQDFQEEWTGLAIFLAPTPNYKPKKDEKNGLMSFFPIILRQKALLTYIVLASLMVTLIDIVGSYY
LQGMLDEYIPDQLISTLGIITIGLIITYIIQQMMSFAKEYLLNVLSLRLVIDVILSYIKHIFTLPMSFFATRRTGEITSR
FSDANQIINAVASTIFSIFLDVTMLILVGGVLLVQNNHLFLLTLISIPIYAIIITAFLKPFEKMNHEVMEANAMVSSSII
EDINGMETIKSLTSESSRYQNIDGEFVDYLEKNFKLQKMNALQTSLKTGAKLILNVVILWYGARLVMDGKISVGQLITFN
ALLSYFQNPIENIISLQTKLQSARVANTRLNEVYLVESEFENDGELSEDSFLDGDISFEKLSYKYGYGRDTLSDINLTIA
KGSKVSLVGPSGSGKTTLAKMMVNFYDPNRGIARINGYDLKVIDKTALRQHISYLPQQAYVFSGTIMDNLTLGAKEGTTQ
EDIIRACEIAEIRSDIEQMPLGYQTELSDGAGVSGGQKQRIALARALLTQAPVLILDEATSSLDVLTEKKIVDNLMAMTD
KTVIFVAHRLSIAQRTDRIIVMDQGKIVEEGSHKELLANKGFYYTLFN

Nucleotide


Download         Length: 2307 bp        

>NTDB_id=1139414 DQM69_RS08975 WP_032672998.1 1842139..1844445(-) (comA/nlmT) [Streptococcus sobrinus strain NCTC10921]
ATGAAGCAGATCACCTATATTATTTTGATTGTAGCTCTTGTTATCGCAGTCAATATTATTTTAGAGGCCTTTAGACGCTA
CTTTAGATCTAAGAGAGGGAAGTCTAGTCCTCAATCATCTCAAGCAGTAGCTGGTTCTTCCAGTTCAGTTGGGCTATTTT
GGCGTAGGCGCTACAAGTTTATTCCTCAAGTGGATACCAGAGACTGTGGTCCAGCAGCCCTAGCTTCAGTAGCCAAGCAC
TATGGTTCGGACTATTCTCTGGCTAGATTGCGAGAGCTTTCAAAGACTGATAAGCAGGGAACGACAGCTCTTGGTTTAGT
AGAAGCTGCCAAGGCTATTGGTTTTGAAACCCGCTCGATCAAGGCTGATATGACTTTGTTTGACTATACGGATTTAACAT
ACCCTTTTATTGTCCATGTGGTTAAGAACAAGCGTCTCCAGCACTATTATGTCGTCTATGGCAATGACAAGAATAATCTG
ATTATTGGCGACCCTGATCCTAATGTCAAGGTTACTCGCATGTCCAAACAGGACTTCCAAGAAGAGTGGACAGGTCTAGC
CATCTTTCTAGCGCCAACCCCCAACTATAAGCCCAAGAAGGATGAAAAAAATGGCCTCATGAGCTTCTTCCCTATTATTT
TAAGGCAGAAGGCCCTCTTGACTTACATTGTTTTAGCCAGTCTGATGGTAACCCTGATTGATATTGTTGGTTCTTACTAT
CTCCAGGGCATGCTGGATGAATACATTCCAGACCAGTTAATTTCAACTCTGGGTATTATTACCATCGGCTTGATTATTAC
CTATATCATTCAGCAGATGATGAGCTTTGCCAAGGAATACTTGCTTAATGTCCTTAGCCTGCGGTTGGTGATTGATGTTA
TTCTATCTTATATCAAGCACATCTTTACCCTGCCTATGTCTTTCTTTGCGACTCGGCGGACAGGGGAAATTACCTCTCGT
TTTTCTGATGCCAATCAGATCATTAATGCTGTCGCGTCAACCATCTTCTCCATCTTCCTGGATGTAACCATGTTAATTCT
GGTTGGTGGGGTGCTTTTGGTGCAAAATAATCACCTCTTCCTCCTGACCCTGATCTCTATCCCAATTTATGCCATTATCA
TCACCGCCTTCCTCAAACCTTTTGAAAAGATGAATCATGAGGTTATGGAAGCTAATGCCATGGTATCTTCTTCTATCATT
GAGGACATTAATGGGATGGAAACCATCAAATCTTTAACCAGTGAATCCAGTCGTTACCAAAATATCGACGGTGAATTCGT
TGATTATTTGGAGAAAAATTTCAAACTTCAAAAGATGAATGCCCTGCAGACCTCACTCAAGACTGGGGCGAAACTCATTC
TCAATGTAGTCATCCTCTGGTATGGGGCACGCTTAGTTATGGATGGTAAGATTTCTGTTGGGCAATTGATTACCTTTAAT
GCTCTCTTGTCTTACTTCCAAAATCCAATTGAAAATATCATCAGCTTGCAAACTAAACTGCAATCAGCGCGTGTAGCCAA
CACCCGTCTTAATGAAGTCTATTTGGTAGAATCCGAGTTTGAAAACGATGGCGAACTCTCAGAAGATAGCTTCCTAGATG
GGGATATCTCCTTTGAGAAACTGTCCTACAAGTATGGTTATGGTCGCGATACCCTTTCAGACATCAACCTGACCATTGCC
AAAGGCTCTAAGGTCAGCTTGGTAGGACCATCAGGCTCTGGTAAGACAACCTTAGCTAAGATGATGGTCAATTTCTATGA
TCCTAACCGAGGGATTGCCCGTATCAACGGCTATGATCTCAAGGTCATTGATAAGACTGCCCTGCGGCAACATATTAGTT
ATTTACCCCAACAAGCCTATGTCTTTTCTGGCACCATCATGGATAACCTAACCCTAGGGGCTAAGGAAGGCACTACCCAG
GAAGACATTATCCGAGCTTGTGAAATTGCAGAAATCCGCTCGGATATTGAGCAGATGCCTCTTGGTTACCAAACAGAACT
CTCTGACGGTGCTGGGGTTTCAGGCGGTCAGAAGCAAAGGATTGCGTTGGCCCGTGCCCTCCTAACTCAGGCCCCTGTCT
TAATTTTGGATGAGGCCACCAGCAGTTTAGATGTCCTGACGGAAAAGAAAATTGTTGATAACCTCATGGCCATGACCGAC
AAGACCGTTATCTTTGTCGCTCACCGATTGAGTATCGCGCAAAGGACAGATCGGATTATCGTCATGGACCAAGGAAAGAT
TGTGGAAGAAGGTAGCCATAAGGAACTCTTGGCTAATAAGGGCTTCTACTACACACTGTTTAACTAA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(57-194)

ABC transporter (ABC_tran)

(552-701)

ABC transporter transmembrane region (ABC_membrane)

(220-489)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

83.203

100

0.832
  comA Streptococcus mitis NCTC 12261

67.643

93.359

0.632
  comA Streptococcus mitis SK321

66.946

93.359

0.625
  comA Streptococcus pneumoniae Rx1

66.806

93.359

0.624
  comA Streptococcus pneumoniae D39

66.806

93.359

0.624
  comA Streptococcus pneumoniae R6

66.806

93.359

0.624
  comA Streptococcus pneumoniae TIGR4

66.527

93.359

0.621
  comA Streptococcus gordonii str. Challis substr. CH1

65.406

92.969

0.608

Multiple sequence alignment