Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB/nlmE   Type   Regulator
Locus tag   DQM69_RS08970 Genome accession   NZ_LS483381
Coordinates   1841202..1842125 (-) Length   307 a.a.
NCBI ID   WP_109982751.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain NCTC10921     
Function   transport of ComC (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1840051..1846130 1841202..1842125 within 0


Gene organization within MGE regions


Location: 1840051..1846130
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM69_RS08965 (NCTC10921_01785) - 1840051..1841040 (-) 990 WP_111687998.1 IS30 family transposase -
  DQM69_RS08970 (NCTC10921_01786) comB/nlmE 1841202..1842125 (-) 924 WP_109982751.1 HlyD family efflux transporter periplasmic adaptor subunit Regulator
  DQM69_RS08975 (NCTC10921_01787) comA/nlmT 1842139..1844445 (-) 2307 WP_032672998.1 peptide cleavage/export ABC transporter Regulator
  DQM69_RS08980 - 1844974..1846130 (-) 1157 Protein_1700 IS256 family transposase -

Sequence

Protein


Download         Length: 307 a.a.        Molecular weight: 35303.96 Da        Isoelectric Point: 10.3329

>NTDB_id=1139413 DQM69_RS08970 WP_109982751.1 1841202..1842125(-) (comB/nlmE) [Streptococcus sobrinus strain NCTC10921]
MNPKLLESAEFYRRRYHNFATVLIVPLVILIIFIGVFLCFAKKEITVISQGEVAPTKVLAVIQSVSDTSIAQNKLDDNTK
VDKGDLLVQYTENAEPEQKDAQKNTIKDRNKRLDKEIEKEEKKTKKKYKKLSKKERKKREKKDQKKKEKKKKDRDSEDKK
ETDHVSLFAPESGVIHTNSKYDGLNILPKWSEIAQIYPDIQKTKTVLITYYVSSDDVVSMEKGQKTRLSLERKGNDKLMI
EGKINSVASSATSTKKGNLFKVTAKVKLSKKDSKLVKYGMTGKTVTVIDKKTYFDYFKDKLLHKVED

Nucleotide


Download         Length: 924 bp        

>NTDB_id=1139413 DQM69_RS08970 WP_109982751.1 1841202..1842125(-) (comB/nlmE) [Streptococcus sobrinus strain NCTC10921]
ATGAATCCAAAATTACTTGAAAGTGCGGAATTTTACCGTCGTCGCTACCATAATTTTGCGACTGTTCTTATTGTGCCCTT
GGTTATCTTGATTATCTTCATTGGTGTTTTCCTCTGCTTTGCCAAAAAGGAAATCACAGTGATTTCTCAAGGTGAAGTGG
CGCCAACAAAGGTATTGGCCGTTATCCAGTCTGTTAGTGACACATCGATTGCACAAAATAAATTAGACGACAACACTAAG
GTTGATAAGGGTGACCTCTTGGTGCAGTACACAGAGAATGCGGAACCAGAACAAAAGGATGCCCAAAAGAATACAATCAA
GGACCGCAATAAGCGCCTAGACAAGGAAATAGAAAAGGAAGAGAAGAAAACAAAGAAAAAGTATAAAAAGCTTTCCAAAA
AGGAAAGGAAGAAACGGGAGAAAAAAGACCAGAAGAAGAAGGAGAAAAAGAAAAAAGACCGAGATTCAGAGGATAAAAAA
GAAACAGACCACGTTTCCCTCTTTGCTCCTGAGTCAGGAGTGATCCATACTAACAGTAAGTATGATGGCCTCAATATCCT
TCCTAAGTGGTCAGAAATTGCCCAAATCTATCCTGATATTCAAAAGACGAAAACCGTCTTAATTACCTACTACGTCTCAT
CTGACGATGTTGTTTCCATGGAGAAGGGACAAAAGACCCGCCTATCGCTTGAGAGAAAAGGAAATGATAAGTTGATGATT
GAGGGGAAAATCAACAGTGTTGCTTCATCAGCCACCTCAACCAAGAAGGGCAATCTCTTCAAAGTTACCGCTAAGGTTAA
ACTGTCTAAAAAAGACAGTAAGCTAGTCAAATATGGAATGACTGGGAAAACAGTCACCGTGATTGATAAGAAGACCTACT
TTGATTACTTCAAGGATAAATTGCTTCACAAGGTGGAGGATTAA

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(167-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB/nlmE Streptococcus mutans UA159

68.404

100

0.684

Multiple sequence alignment