Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   DQM75_RS07595 Genome accession   NZ_LS483380
Coordinates   1608796..1610952 (+) Length   718 a.a.
NCBI ID   WP_111692694.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC11824     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1603796..1615952
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM75_RS07540 - 1603878..1604117 (+) 240 WP_337660704.1 helix-turn-helix transcriptional regulator -
  DQM75_RS07545 (NCTC11824_01522) - 1604209..1604799 (-) 591 WP_111692690.1 GNAT family N-acetyltransferase -
  DQM75_RS07550 (NCTC11824_01523) - 1605049..1605462 (-) 414 WP_012679937.1 hypothetical protein -
  DQM75_RS07560 (NCTC11824_01524) - 1606125..1606328 (-) 204 WP_012516109.1 Blp family class II bacteriocin -
  DQM75_RS07565 (NCTC11824_01525) - 1606345..1606599 (-) 255 WP_111692691.1 Blp family class II bacteriocin -
  DQM75_RS07570 (NCTC11824_01526) - 1606753..1607049 (-) 297 WP_111692692.1 bacteriocin immunity protein -
  DQM75_RS07575 (NCTC11824_01527) - 1607049..1607267 (-) 219 WP_037579371.1 leucocin A/sakacin P family class II bacteriocin -
  DQM75_RS07585 (NCTC11824_01528) - 1607985..1608281 (-) 297 WP_111692935.1 bacteriocin immunity protein -
  DQM75_RS07590 (NCTC11824_01529) - 1608288..1608536 (-) 249 WP_111692693.1 garvicin Q family class II bacteriocin -
  DQM75_RS07595 (NCTC11824_01530) comA/nlmT 1608796..1610952 (+) 2157 WP_111692694.1 peptide cleavage/export ABC transporter Regulator
  DQM75_RS07600 (NCTC11824_01531) - 1610963..1612321 (+) 1359 WP_111692695.1 bacteriocin secretion accessory protein -
  DQM75_RS07605 (NCTC11824_01532) - 1612421..1612555 (+) 135 WP_111692696.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  DQM75_RS10200 (NCTC11824_01533) - 1612673..1614007 (-) 1335 WP_111692697.1 sensor histidine kinase -
  DQM75_RS07615 (NCTC11824_01534) comE/blpR 1614007..1614756 (-) 750 WP_042671079.1 LytR/AlgR family response regulator transcription factor Regulator
  DQM75_RS07620 (NCTC11824_01535) - 1615383..1615586 (-) 204 WP_012516120.1 TmhB bacteriocin enhancer peptide -
  DQM75_RS07625 (NCTC11824_01536) - 1615603..1615860 (-) 258 WP_111678353.1 Blp family class II bacteriocin -

Sequence

Protein


Download         Length: 718 a.a.        Molecular weight: 80580.71 Da        Isoelectric Point: 7.7849

>NTDB_id=1139347 DQM75_RS07595 WP_111692694.1 1608796..1610952(+) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
MTLFYKRTFVPQIDARDCGVAALASIARYYGSDYSLAHLRELAKTNKEGTTALGIVIAAKEIGFETRPIQADMTLFDMAD
VPYPLIVHVNKEGKLQHYYVVYKSKKDYLIIGDPNPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFP
LIFKQRALIFYIVLASVLVTVINIAGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYILQQLMSFSRDYLLTVLSQRLTI
DVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSIIDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYT
LIICAFIKPFEQMNHDVMQSNAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFRLSKYTILQATLKQGAQ
LILNIIILWFGAQLVINGRISIGQLITFNTLLAYFTTPLENIINLQTKLQAAKVANNRLNEVYLVESEFKASQALYDLSL
LQGDIQFEAVSYRYGFGKDTLSDITLTIKQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQY
INYLPQQAYIFNGSILENLTLGAKQGISQEDILNACEIADIRHDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTQA
PILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIAERTDQIVVLNQGQIIETGSHQELMKQGGFYYHLFSE

Nucleotide


Download         Length: 2157 bp        

>NTDB_id=1139347 DQM75_RS07595 WP_111692694.1 1608796..1610952(+) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
ATGACACTCTTTTATAAAAGAACCTTTGTACCACAAATAGATGCCAGAGATTGTGGCGTAGCTGCTCTAGCTTCGATCGC
AAGGTATTATGGTTCAGATTATTCATTAGCTCATTTGAGAGAATTAGCAAAGACCAATAAGGAAGGGACAACAGCCCTCG
GTATTGTCATAGCTGCTAAGGAAATAGGGTTTGAAACCAGACCCATTCAAGCGGATATGACCCTCTTTGATATGGCAGAT
GTGCCCTATCCATTGATCGTCCATGTCAATAAAGAAGGAAAGCTACAGCACTACTATGTGGTCTACAAATCTAAAAAAGA
CTATCTTATCATTGGTGATCCCAATCCAATGGTCAAGGTCACAAAAATGTCCAAGGAACGCTTTGCTTCAGAATGGACAG
GTGTCACCATATGCCTTGCTCCTAAGCCAAATTATAAACCACATAAAGACCAAAAAAATGGACTATTAGGCTTCTTTCCG
CTTATTTTTAAACAGCGAGCCCTTATTTTTTATATCGTGTTAGCTTCTGTCTTGGTAACGGTCATTAATATTGCTGGTTC
ATACTATCTCCAAGGGATTTTAGACGAGTATATTCCAAATCAACTGAAATCTACCTTAGGGATTGTATCAATTGGTCTCA
TCATTACCTATATACTCCAGCAGCTAATGAGCTTTTCTAGAGATTATCTTTTAACTGTCCTTAGCCAACGTCTTACGATT
GATGTGATCCTGTCCTATATCCGCCATATTTTCGAATTGCCGATGTCCTTTTTTGCAACACGTCGAACAGGTGAGGTAAC
CTCGCGCTTTACAGATGCTAACTCTATCATTGACGCACTCGCTTCAACCATTTTATCTCTCTTTCTAGACCTCTCTATAT
TAGCTATTGTCGGAAGTGTTCTTTTGGTGCAAAATAGCAGGCTTTTTCTGCTGTCCCTGATTTCTATTCCAGTATACACC
CTTATCATATGTGCCTTTATAAAGCCGTTTGAACAAATGAATCATGATGTGATGCAAAGCAATGCCATGCTAAGCTCTGC
TATTATCGAAGATATCAACGGGATCGAAACCATAAAATCACTAACCAGTGAAGAAAACCGTTACCAAAAAATTGACAGCG
ACTTTGTGGATTACCTCGATAAGTCCTTTAGGCTTAGTAAATATACCATCTTACAAGCCACACTTAAGCAAGGAGCGCAG
CTAATTCTGAATATCATCATTCTTTGGTTTGGGGCTCAACTGGTTATTAATGGTAGGATTTCAATTGGGCAGTTAATTAC
CTTTAACACACTTCTTGCCTATTTTACAACCCCTTTAGAAAATATCATTAATCTTCAAACCAAGCTCCAAGCAGCTAAGG
TTGCCAACAATCGTCTCAATGAGGTCTATCTTGTAGAGTCCGAATTTAAAGCCTCGCAAGCCTTATACGATTTATCGCTC
TTACAGGGTGACATTCAGTTTGAAGCTGTTTCCTATAGGTATGGCTTTGGCAAGGATACATTATCAGATATTACATTAAC
CATTAAGCAGGGAGCAAAAGTAACCCTTGTTGGTGTCAGCGGCTCAGGAAAAACAACCCTAGCCAAGATGCTCGTCAATT
TCTTTGAACCTTATAAGGGACGTATAACCATCAACCAAAACGATCTCAAGACCATTGATAAAAAGAATCTTCGACAATAC
ATCAACTACCTTCCACAACAAGCCTATATCTTTAATGGATCTATCTTAGAAAATCTAACCTTGGGAGCCAAGCAAGGCAT
CAGCCAGGAAGACATTCTTAACGCCTGTGAGATTGCTGACATTCGTCACGACATCGAGCAAATGCCAATGGGATACCAAA
CCGAGCTCTCTGATGGGGCTGGCTTATCTGGCGGACAAAAACAGAGAATTGCACTTGCTAGAGCATTACTAACCCAAGCT
CCTATACTAGTTCTTGATGAAGCAACCAGCGGACTTGACATACTGACAGAAAAGAAAATCATTGACCGTCTCATGAACAT
GACAGACAAAACGATTATTTTCGTTGCCCACCGGCTTAGTATCGCAGAGCGCACTGATCAGATTGTTGTTCTTAATCAAG
GGCAAATCATTGAAACAGGCAGCCACCAGGAATTAATGAAACAAGGTGGATTTTATTACCACCTATTTAGTGAATAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(169-439)

ABC transporter (ABC_tran)

(501-650)

Peptidase C39 family (Peptidase_C39)

(8-143)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

70.432

99.861

0.703
  comA Streptococcus mitis SK321

67.461

99.304

0.67
  comA Streptococcus mitis NCTC 12261

67.181

99.304

0.667
  comA Streptococcus pneumoniae Rx1

66.76

99.304

0.663
  comA Streptococcus pneumoniae D39

66.76

99.304

0.663
  comA Streptococcus pneumoniae R6

66.76

99.304

0.663
  comA Streptococcus pneumoniae TIGR4

66.48

99.304

0.66
  comA Streptococcus gordonii str. Challis substr. CH1

65.077

99.304

0.646

Multiple sequence alignment