Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   DQM75_RS07615 Genome accession   NZ_LS483380
Coordinates   1614007..1614756 (-) Length   249 a.a.
NCBI ID   WP_042671079.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC11824     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1609007..1619756
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM75_RS07600 (NCTC11824_01531) - 1610963..1612321 (+) 1359 WP_111692695.1 bacteriocin secretion accessory protein -
  DQM75_RS07605 (NCTC11824_01532) - 1612421..1612555 (+) 135 WP_111692696.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  DQM75_RS10200 (NCTC11824_01533) - 1612673..1614007 (-) 1335 WP_111692697.1 sensor histidine kinase -
  DQM75_RS07615 (NCTC11824_01534) comE/blpR 1614007..1614756 (-) 750 WP_042671079.1 LytR/AlgR family response regulator transcription factor Regulator
  DQM75_RS07620 (NCTC11824_01535) - 1615383..1615586 (-) 204 WP_012516120.1 TmhB bacteriocin enhancer peptide -
  DQM75_RS07625 (NCTC11824_01536) - 1615603..1615860 (-) 258 WP_111678353.1 Blp family class II bacteriocin -
  DQM75_RS07630 (NCTC11824_01537) rlmD 1616181..1617548 (-) 1368 WP_042671083.1 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD -
  DQM75_RS07635 (NCTC11824_01538) - 1617545..1618513 (-) 969 WP_111692698.1 DNA-binding protein -
  DQM75_RS07640 (NCTC11824_01539) recX 1618577..1619353 (+) 777 WP_111692699.1 recombination regulator RecX -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29227.69 Da        Isoelectric Point: 8.4602

>NTDB_id=1139348 DQM75_RS07615 WP_042671079.1 1614007..1614756(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRPHQLLSAIKKNCGQQLFFLDIEIKNEDKKGLEVARQIRQIN
PDAMIVFVTTHSEFMPLAFQYQVSALDYIDKELPHTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINPRNVVRVDKIERVVYFRNGSSCLIARSKMNSVLTT
IENLHRGDN

Nucleotide


Download         Length: 750 bp        

>NTDB_id=1139348 DQM75_RS07615 WP_042671079.1 1614007..1614756(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
GTGAGAGTAGTTATTTTAGAAGATGATATGATTCAGCAGAGATATTTAGAAAAGCTCATTAAAGAGCTTGAGGTTAAGCA
CCAGCTATTATTTCAAGGACTTGACTGTTTTGGAAGGCCTCATCAGCTATTAAGTGCTATCAAGAAGAACTGTGGTCAGC
AGCTATTCTTTTTAGATATTGAGATAAAAAATGAGGACAAAAAAGGGCTTGAGGTTGCTAGGCAAATTCGTCAGATAAAT
CCAGATGCGATGATTGTTTTTGTAACGACTCACTCGGAATTTATGCCCTTGGCTTTTCAGTATCAGGTATCTGCTTTGGA
CTATATCGATAAAGAGCTGCCTCACACTGAGTTTGTTCAACGGGTAGAGACTGCTTTATTATATGCTGTGCGGCAAAATA
GTGAAACGATAGCGGAAAGTGCTTTTTATTTTACATCTCGTTATGCTCAGGTACAGGTGCCTTTTAATGATATCCTGTAT
ATTGAGACATCGTCACGAGCGCATCGTGTCAATTTGTATACAAAAAAGGAGAGAATGCAATTTACAGGGACTTTGACGGA
TATTTTGAAGCAAGAGTCTCGTTTTTTGCAATGTCATCGTTCTTTTTTGATTAATCCTAGGAATGTCGTTAGGGTAGATA
AGATTGAGCGAGTGGTTTATTTTCGAAATGGCTCTAGCTGCTTAATTGCTCGTAGTAAAATGAACAGTGTTTTAACAACA
ATTGAGAACCTACATAGAGGAGATAATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

52.61

100

0.526
  comE/comE1 Streptococcus equinus JB1

40.167

95.984

0.386

Multiple sequence alignment