Detailed information NTG1139285

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQM61_RS04530
• Genome accession: NZ_LS483379
• Coordinates: 869887..870723 (+)
• Length: 278 a.a.
• NCBI ID: WP_023610312.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC10874
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 864887..875723

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM61_RS04500 (NCTC10874_00888)	-	865441..865809 (+)	369	WP_023610297.1	hypothetical protein	-
DQM61_RS04505 (NCTC10874_00889)	-	865859..866770 (-)	912	WP_023610321.1	diacylglycerol/lipid kinase family protein	-
DQM61_RS04510 (NCTC10874_00890)	trhA	866887..867537 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DQM61_RS04515 (NCTC10874_00891)	-	867534..867974 (-)	441	WP_011017769.1	DUF1836 domain-containing protein	-
DQM61_RS04520 (NCTC10874_00892)	ylqF	868193..869041 (+)	849	WP_023610309.1	ribosome biogenesis GTPase YlqF	-
DQM61_RS04525 (NCTC10874_00893)	-	869031..869822 (+)	792	WP_023610315.1	ribonuclease HII	-
DQM61_RS04530 (NCTC10874_00894)	dprA	869887..870723 (+)	837	WP_023610312.1	DNA-processing protein DprA	Machinery gene
DQM61_RS04535 (NCTC10874_00895)	topA	870831..872960 (+)	2130	WP_023610295.1	type I DNA topoisomerase	-
DQM61_RS04540 (NCTC10874_00896)	trmFO	873095..874441 (+)	1347	WP_023610318.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31068.09 Da
• Isoelectric Point: 9.2518

>NTDB_id=1139285 DQM61_RS04530 WP_023610312.1 869887..870723(+) (dprA) [Streptococcus pyogenes strain NCTC10874]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDHFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1139285 DQM61_RS04530 WP_023610312.1 869887..870723(+) (dprA) [Streptococcus pyogenes strain NCTC10874]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCACTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAAGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367