Detailed information NTG1139125

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: DQM54_RS07790
• Genome accession: NZ_LS483375
• Coordinates: 1575060..1577300 (-)
• Length: 746 a.a.
• NCBI ID: WP_111723981.1
• Uniprot ID: -
• Organism: Streptococcus gordonii strain NCTC3165
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1570060..1582300

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM54_RS07760 (NCTC3165_01546)	-	1570329..1570826 (-)	498	WP_111724306.1	DUF1648 domain-containing protein	-
DQM54_RS07765 (NCTC3165_01547)	-	1570813..1571097 (-)	285	WP_111723977.1	autorepressor SdpR family transcription factor	-
DQM54_RS07770 (NCTC3165_01548)	-	1571075..1571863 (-)	789	WP_111723978.1	YhfC family intramembrane metalloprotease	-
DQM54_RS07775 (NCTC3165_01549)	-	1572069..1573142 (-)	1074	WP_111723979.1	serine hydrolase	-
DQM54_RS07780 (NCTC3165_01550)	-	1573254..1573859 (-)	606	WP_045773124.1	superoxide dismutase	-
DQM54_RS07785 (NCTC3165_01551)	holA	1573932..1574969 (-)	1038	WP_111723980.1	DNA polymerase III subunit delta	-
DQM54_RS07790 (NCTC3165_01552)	comEC/celB	1575060..1577300 (-)	2241	WP_111723981.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
DQM54_RS07795 (NCTC3165_01553)	comEA/celA/cilE	1577284..1577949 (-)	666	WP_111723982.1	helix-hairpin-helix domain-containing protein	Machinery gene
DQM54_RS07800 (NCTC3165_01554)	-	1578046..1578573 (-)	528	WP_111723983.1	HXXEE domain-containing protein	-
DQM54_RS07805 (NCTC3165_01555)	-	1578612..1579352 (-)	741	WP_041789898.1	lysophospholipid acyltransferase family protein	-
DQM54_RS07810 (NCTC3165_01556)	-	1579482..1581851 (+)	2370	WP_111723984.1	cation-translocating P-type ATPase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 85516.43 Da
• Isoelectric Point: 9.8787

>NTDB_id=1139125 DQM54_RS07790 WP_111723981.1 1575060..1577300(-) (comEC/celB) [Streptococcus gordonii strain NCTC3165]
MSQWIKKLPLSPIYLCFLLVWLYFAIYSGEKLAYLGVFLLIARLIWHYPRKKWLPTVAILIAFSIFFYARRELAERTFQS
QPAPARQVLVLPDTVKVNGDSLFFRGRIDGRLYQLYYKLASPREKKSFQKLADLVTLEIEGEFNLAEGRRNFSGFDYQAY
LKSQGIYRTVKISRIMSSHSSQSINPFDWLSVWRRKALVFIKSTFPSPMSHYMTGLLFGDLDIEFAEMNDLYSSLGIIHL
FALSGMQVGFFMDAFRKILLRIGLRMETVDWLQFPLSFIYAGLTGFSVSVVRSLVQKLLSQFGVRRLDNFAMAMMALMFL
MPSFLLTTGGVLSCAYAFIITMLDFEDFSGFRKAVLESLSISLGILPILIHYFAEFQPWSILLTFLFSIVFDTFMLPLLS
LIFLISPLFAFTQVNVFFQWLEMVIRWVASLSTRPIILGQPNLPLLIILLLVLALLYDFRKQKKIRAGLSLLAILLFFLS
KYPLQNEITVVDIGQGDSIFLRDVRGRTIVIDTGGRVEIGKKEAWQERVRKSNAETTLIPYLKSRGVDRLDKLVLTHTDT
DHMGDMLELAKHFSIREIYVSKGSMTQVDFVDKLKKMKAKVHVVEVGDRLPIFDSALEVLYPLGQGDGGNDDSIVLYGEF
FRTKFLFTGDLEAPGEGQMVTAYPDLRVDVLKAGHHGSKGSSSPEFLEHIKPKLALISAGKNNRYQHPHKETLDRFEKIQ
TKIFRTDEQGAIRFKGWNSWQIETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=1139125 DQM54_RS07790 WP_111723981.1 1575060..1577300(-) (comEC/celB) [Streptococcus gordonii strain NCTC3165]
ATGTCACAGTGGATTAAAAAACTTCCCCTTTCACCAATCTATTTGTGCTTTCTTTTGGTTTGGCTCTATTTCGCTATTTA
TAGTGGGGAAAAGCTCGCTTATCTGGGAGTTTTTCTGCTTATAGCTCGACTAATCTGGCATTATCCAAGAAAGAAATGGT
TGCCAACTGTAGCTATCCTAATTGCTTTTTCTATCTTTTTTTATGCTAGACGAGAGTTGGCGGAGCGAACCTTTCAGTCT
CAACCGGCTCCAGCAAGACAAGTTCTTGTTTTACCAGATACGGTTAAAGTGAATGGAGATTCCCTGTTTTTCCGTGGTAG
AATAGACGGAAGACTTTATCAGCTCTACTACAAATTAGCAAGTCCAAGAGAGAAAAAATCATTTCAAAAACTAGCAGACT
TGGTCACTTTAGAAATAGAAGGAGAGTTTAATCTAGCAGAAGGTCGGCGAAATTTTTCTGGTTTTGACTATCAGGCTTAT
TTAAAAAGCCAGGGAATTTATCGGACAGTTAAGATCAGTAGGATTATGTCCAGTCACTCTAGTCAATCTATCAATCCATT
TGATTGGCTGTCTGTTTGGCGTAGGAAGGCTTTGGTTTTCATTAAGTCTACTTTTCCAAGCCCGATGAGTCACTACATGA
CAGGACTTTTGTTTGGAGATTTAGATATTGAATTTGCAGAGATGAATGACTTGTACTCAAGTTTAGGAATTATCCATCTT
TTTGCTTTATCAGGAATGCAGGTTGGCTTTTTTATGGATGCCTTTCGGAAAATTCTTCTGCGCATAGGCTTAAGGATGGA
AACGGTAGATTGGTTGCAATTCCCGTTGTCCTTTATTTATGCAGGTTTGACTGGATTTTCTGTGTCAGTAGTGAGAAGTT
TAGTGCAAAAATTATTGTCTCAATTTGGAGTGAGGCGCTTGGATAATTTTGCTATGGCCATGATGGCCTTGATGTTTCTC
ATGCCGAGTTTTCTCCTGACAACAGGCGGAGTCCTATCTTGCGCTTATGCCTTTATCATCACTATGTTGGATTTTGAGGA
TTTTAGTGGCTTTCGTAAAGCCGTACTAGAGAGTTTAAGTATCTCGTTAGGCATTTTACCGATTCTTATCCACTATTTTG
CAGAATTCCAACCTTGGTCTATCCTCTTGACCTTCCTTTTTTCAATCGTCTTTGATACATTTATGTTACCTCTCTTGAGT
CTAATTTTTCTCATTTCGCCTTTGTTTGCCTTCACTCAAGTTAATGTCTTCTTCCAATGGCTGGAAATGGTGATTCGTTG
GGTAGCTAGTTTGTCAACAAGGCCGATAATTTTAGGACAGCCAAATCTGCCTTTGCTTATTATTCTCCTGCTGGTCTTAG
CCTTGCTCTATGACTTTAGAAAACAAAAAAAGATTAGGGCTGGTCTGAGTCTCTTAGCAATCTTACTATTTTTCCTAAGT
AAATATCCTTTACAAAATGAAATCACAGTGGTAGATATTGGGCAGGGAGACAGTATATTTCTGAGGGATGTCAGAGGTAG
GACTATCGTGATTGATACAGGAGGACGGGTGGAGATTGGAAAAAAAGAAGCTTGGCAAGAGCGCGTGAGAAAAAGTAATG
CGGAAACGACCTTGATCCCTTATCTAAAAAGCCGAGGAGTGGATAGATTGGATAAATTGGTCTTGACTCACACCGATACA
GACCATATGGGAGATATGTTGGAGTTAGCTAAGCACTTTTCTATCCGAGAAATTTATGTTTCTAAAGGAAGTATGACTCA
AGTTGATTTTGTAGACAAGTTAAAGAAGATGAAAGCTAAAGTTCATGTGGTCGAGGTGGGAGATCGGCTTCCTATCTTTG
ATTCGGCCCTTGAAGTGCTCTATCCACTAGGTCAAGGAGATGGTGGTAATGATGACTCGATTGTCTTGTATGGTGAATTT
TTCCGGACCAAGTTTCTTTTCACAGGAGATTTAGAAGCTCCAGGTGAAGGTCAGATGGTGACAGCCTATCCAGATTTAAG
AGTAGATGTGCTCAAAGCTGGGCATCATGGTTCTAAAGGATCTTCTAGTCCAGAATTTCTAGAGCATATTAAGCCTAAGT
TGGCCTTGATTTCAGCTGGTAAAAACAACCGTTATCAACATCCCCATAAGGAAACTTTAGATAGATTCGAAAAAATCCAG
ACTAAGATTTTTCGGACAGATGAGCAGGGAGCTATTCGATTTAAAGGCTGGAATTCTTGGCAGATAGAAACGGTTCGCTA
G

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (35-174)

• Metallo-beta-lactamase superfamily (Lactamase_B) (494-700)

• Competence protein (Competence) (216-460)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	57.564	100	0.576
comEC/celB	Streptococcus mitis NCTC 12261	56.702	100	0.567
comEC/celB	Streptococcus pneumoniae TIGR4	56.359	100	0.564
comEC/celB	Streptococcus pneumoniae Rx1	55.823	100	0.559
comEC/celB	Streptococcus pneumoniae D39	55.823	100	0.559
comEC/celB	Streptococcus pneumoniae R6	55.823	100	0.559
comEC	Lactococcus lactis subsp. cremoris KW2	49.597	99.732	0.495