Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   DQM56_RS02855 Genome accession   NZ_LS483368
Coordinates   575842..577995 (+) Length   717 a.a.
NCBI ID   WP_012678371.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC6176     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 570842..582995
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM56_RS02830 (NCTC6176_00567) metG 571047..573050 (+) 2004 WP_043038707.1 methionine--tRNA ligase -
  DQM56_RS02835 (NCTC6176_00568) - 573608..574501 (+) 894 WP_024273139.1 helix-turn-helix domain-containing protein -
  DQM56_RS02845 (NCTC6176_00570) - 574854..574994 (+) 141 WP_012515166.1 hypothetical protein -
  DQM56_RS10005 (NCTC6176_00571) - 575107..575265 (+) 159 WP_021320463.1 hypothetical protein -
  DQM56_RS02850 (NCTC6176_00573) - 575448..575615 (+) 168 WP_012515168.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  DQM56_RS02855 (NCTC6176_00574) comA 575842..577995 (+) 2154 WP_012678371.1 peptide cleavage/export ABC transporter ComA Regulator
  DQM56_RS02860 (NCTC6176_00575) comB 578010..579377 (+) 1368 WP_012515170.1 bacteriocin secretion accessory protein Regulator
  DQM56_RS02865 (NCTC6176_00576) - 579886..580122 (+) 237 WP_024273149.1 hypothetical protein -
  DQM56_RS02870 (NCTC6176_00577) nrdF 580580..581593 (+) 1014 WP_012678369.1 class 1b ribonucleoside-diphosphate reductase subunit beta -
  DQM56_RS02875 (NCTC6176_00578) nrdI 581595..582005 (+) 411 WP_043038720.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80511.51 Da        Isoelectric Point: 9.0606

>NTDB_id=1138887 DQM56_RS02855 WP_012678371.1 575842..577995(+) (comA) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
MKFRRKHYRAQVDTRDCGVASLAMIYGYYGSYYSLATLREAAKTTQEGTTAFGLVKVSEALGFETRAIRADMSLFDVEGL
SYPFIAHVLKKGKFLHYYVVTGQDKKYIHIADPDPTVKLTCLSRQRFASEWTGVTIFIAPTPEYKPHKEKKNSLLDFVPL
LAKQKGLITNIVVATLLVMIINIIGSYYLQSIIDTYVPSVMKNTLGIISVGLVIVYALQQVISYAQEYLLLILGQRLSID
VILSYIKHIFNLPMSFFATRRTGEIVSRFNDANSIIDALASTILSIFLDVSVIVIISLVLFSQNVNLFVISLLALPIYAV
IIFAFMKPFERMNQETMEANSIMSSSIIEDINGIETIKSLTSEKIRYQKIDKEFVAYLKKSFNYSRAESQQRALKKVAQL
ILNVSILWIGANLVMDGKMSLGQLITYNSLLIYFTNPLENIINLQTKLQTAQVANNRLNEVYLVESEFSEKKNVQDLSLT
SGDIKFNDVSYRYGYGKDVLSEINLHIKRGSKVAFVGISGSGKTTLAKMIVSFFEPSKGEISLNNVNLNQIDKHALRQHI
NYLPQQPYVFNGTILENLLLGAREGTTQEDIMKAVELAEIKSDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDS
PVLILDEATSNLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEHVVVLDKGKIIEQGTHRDLVSQNGFYAHLVNS

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=1138887 DQM56_RS02855 WP_012678371.1 575842..577995(+) (comA) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
ATGAAATTTAGAAGAAAACACTACCGTGCTCAGGTTGATACTCGCGATTGTGGCGTAGCTTCTCTGGCCATGATTTACGG
TTATTATGGATCGTATTATTCGCTAGCAACGTTACGTGAAGCTGCAAAGACAACGCAGGAAGGGACTACAGCTTTTGGTT
TAGTCAAAGTTTCTGAGGCGCTTGGGTTTGAAACGAGAGCTATTAGGGCTGACATGAGTTTATTTGATGTGGAAGGATTA
TCTTATCCTTTTATTGCCCATGTTCTAAAAAAAGGTAAGTTCCTTCATTATTATGTGGTAACAGGACAAGATAAAAAATA
TATTCATATTGCAGATCCAGATCCAACTGTAAAGTTGACTTGTCTTTCTCGTCAGCGATTTGCTTCAGAGTGGACAGGTG
TGACAATTTTTATCGCTCCTACTCCTGAATACAAACCTCACAAGGAAAAGAAAAATAGTCTGCTAGATTTTGTGCCTCTC
CTAGCAAAGCAAAAAGGATTGATTACTAATATCGTTGTGGCAACGCTTTTGGTAATGATTATCAATATTATTGGTTCGTA
TTATCTTCAATCAATCATTGATACCTATGTTCCTAGTGTGATGAAGAATACACTAGGTATTATTTCCGTAGGTTTGGTTA
TTGTCTATGCCCTTCAACAAGTGATCTCATATGCGCAAGAGTATTTATTGCTGATATTAGGGCAACGTTTATCTATTGAT
GTAATTCTTTCTTATATCAAACATATTTTCAACCTTCCTATGTCTTTTTTCGCGACGAGAAGGACCGGGGAAATTGTTTC
TCGTTTTAATGATGCTAATTCAATCATTGATGCTTTAGCAAGTACAATTTTATCTATTTTCCTTGATGTTTCTGTCATTG
TAATTATATCTCTTGTTCTTTTTTCGCAGAATGTAAATCTATTTGTTATCAGTTTGCTTGCTCTGCCTATCTATGCAGTG
ATTATCTTTGCCTTCATGAAGCCATTTGAACGGATGAATCAAGAGACAATGGAAGCAAATTCAATCATGTCATCTTCTAT
TATTGAAGATATAAACGGTATTGAGACTATTAAATCATTAACTAGCGAAAAGATAAGATACCAAAAAATAGATAAAGAAT
TTGTAGCTTATCTTAAGAAATCTTTCAACTATAGTAGGGCAGAAAGCCAACAACGAGCATTGAAAAAAGTAGCTCAGCTT
ATCCTAAACGTGAGCATACTCTGGATAGGAGCCAATCTGGTTATGGACGGAAAAATGAGTTTAGGTCAACTGATTACCTA
TAACTCTCTCCTAATCTACTTTACAAATCCTCTGGAGAATATTATCAATCTTCAAACGAAACTTCAAACCGCTCAAGTCG
CTAATAATCGATTGAATGAGGTATATCTAGTTGAATCCGAGTTCTCTGAAAAGAAGAATGTTCAAGACTTATCTTTGACC
TCTGGTGACATAAAATTCAATGATGTTAGCTATCGATATGGATATGGAAAAGATGTTTTATCAGAAATAAATTTGCATAT
TAAACGAGGAAGCAAGGTTGCTTTTGTTGGGATTTCAGGTTCTGGAAAAACGACTTTAGCTAAGATGATTGTCAGTTTCT
TTGAACCAAGCAAAGGCGAAATATCATTAAATAATGTGAATCTAAATCAAATTGACAAACATGCTCTTCGCCAGCACATT
AACTATCTTCCTCAACAACCTTACGTATTTAATGGGACAATCCTTGAGAATTTACTTCTTGGAGCACGTGAAGGGACGAC
TCAAGAAGACATTATGAAGGCAGTAGAATTGGCTGAAATCAAGTCTGATATTGAACGTATGCCTTTGAATTATCAAACAG
AGTTAACCTCAGATGGTGCAGGGATTTCTGGAGGTCAACGTCAACGTATTGCCTTAGCAAGGGCATTATTGACAGATTCT
CCTGTTTTGATATTAGACGAAGCTACAAGTAACTTGGATATTTTGACTGAGAAGCGAATTGTTGATAACCTGATGGCTTT
AGATAAAACCTTGATATTTATTGCTCACCGTTTAACTATTGCAGAGCGTACAGAGCATGTCGTCGTTTTGGATAAAGGAA
AGATCATAGAGCAAGGAACACACAGAGACCTTGTTTCTCAGAATGGCTTTTATGCTCACTTGGTCAATAGTTAG

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(170-438)

ABC transporter (ABC_tran)

(500-650)

Peptidase C39 family (Peptidase_C39)

(6-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

82.008

100

0.82
  comA Streptococcus mitis SK321

81.59

100

0.816
  comA Streptococcus pneumoniae Rx1

81.59

100

0.816
  comA Streptococcus pneumoniae D39

81.59

100

0.816
  comA Streptococcus pneumoniae R6

81.59

100

0.816
  comA Streptococcus pneumoniae TIGR4

81.311

100

0.813
  comA Streptococcus gordonii str. Challis substr. CH1

78.522

100

0.785
  comA/nlmT Streptococcus mutans UA159

62.762

100

0.628

Multiple sequence alignment