Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   DQM60_RS01475 Genome accession   NZ_LS483366
Coordinates   269416..271512 (+) Length   698 a.a.
NCBI ID   WP_111686473.1    Uniprot ID   -
Organism   Streptococcus salivarius strain NCTC7366     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 264416..276512
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM60_RS01450 (NCTC7366_00288) trkA 264505..265854 (-) 1350 WP_014633874.1 Trk system potassium transporter TrkA -
  DQM60_RS01455 (NCTC7366_00290) - 266132..266641 (+) 510 WP_049529100.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  DQM60_RS01460 (NCTC7366_00292) - 266951..267508 (+) 558 WP_014633876.1 ECF transporter S component -
  DQM60_RS01465 (NCTC7366_00293) - 267511..268161 (+) 651 WP_014633877.1 phosphatase PAP2 family protein -
  DQM60_RS01470 (NCTC7366_00294) comR 268342..269241 (+) 900 WP_045001949.1 helix-turn-helix transcriptional regulator Regulator
  DQM60_RS01475 (NCTC7366_00295) comA 269416..271512 (+) 2097 WP_111686473.1 peptide cleavage/export ABC transporter Regulator
  DQM60_RS01480 (NCTC7366_00296) - 271623..271955 (+) 333 WP_014633880.1 DUF805 domain-containing protein -
  DQM60_RS01485 (NCTC7366_00297) - 272007..273398 (-) 1392 WP_014633611.1 DUF4153 domain-containing protein -
  DQM60_RS01490 (NCTC7366_00298) - 273805..274320 (+) 516 WP_002886548.1 AmiS/UreI family transporter -
  DQM60_RS01495 (NCTC7366_00299) - 274345..274647 (+) 303 WP_002886558.1 urease subunit gamma -
  DQM60_RS01500 (NCTC7366_00300) - 274659..274970 (+) 312 WP_002886559.1 urease subunit beta -

Sequence

Protein


Download         Length: 698 a.a.        Molecular weight: 78451.44 Da        Isoelectric Point: 9.0880

>NTDB_id=1138758 DQM60_RS01475 WP_111686473.1 269416..271512(+) (comA) [Streptococcus salivarius strain NCTC7366]
MSKYPYISQVDQRDCGVAALAMILKHYGSSYSLAYLRELAQTSREGTSALGLVEVAKQLGLETQAIRADLDLFKQESLSY
PFIAHVVKEGGLQHYYTVFGQIKGKLVIGDPDPSKKVIKMPLEEFAKEWTGVALFFVPGETYTKYKEDVPGLLSFLPILF
RRKGLIAVIVLLSFLVTLVNIIGSYYLQSIIDRLIPQEAYTLLTMISLGLCISYLAQQVFTFFKDYLLHRLGNYLSIAVI
LPYIKHVLSLPISFFSSRRTGEITSRFGDANTIIDALASTILSIFLDVTIVMTLAVALILQNQSLFVMTLTVVPLYVLII
LAFYKLFEKENYQLMEANSQVNTAVIDDLRGIETLKSLRVEERRYQEIEVKFHDYLKKSLSKAKWQLTQDGLKTGVQLVS
NVFILWYGAQLVMEGQLSAGQLITYNMLLNYFTTPLINIINLQSKIQQAKVANNRLQEVYVVDKEEKGKLKELSFKQLAL
KGVSHRFSYQQETLSKIDLTIHKGEKIALMGKSGSGKTTLAKMLSGYYTKSSGHVTLDKDAISHAELRQMVTYVPQQTYV
FTGTILENLLLGFEGEVDEKKLLKVCQQADILEDIQKMPLGFQTQVSEDGGLSGGQKQRLAIARALLSQQPILIFDEATS
GLDSDTESRVMANLAKIKRTMIFIAHRNSVRQHVGRVVTMVSGQIESDSPNFNPFQFI

Nucleotide


Download         Length: 2097 bp        

>NTDB_id=1138758 DQM60_RS01475 WP_111686473.1 269416..271512(+) (comA) [Streptococcus salivarius strain NCTC7366]
ATGTCAAAATATCCATATATTTCACAGGTTGATCAGCGTGATTGTGGTGTCGCTGCCTTGGCCATGATTCTTAAACACTA
TGGTTCATCTTATAGTTTAGCTTATTTGCGGGAGTTGGCTCAGACTTCTCGTGAAGGCACTTCTGCGCTTGGTTTGGTTG
AAGTGGCCAAGCAGTTGGGCCTTGAAACTCAGGCTATTCGTGCGGATTTAGACTTGTTTAAACAAGAAAGCCTATCTTAT
CCTTTTATTGCACATGTGGTTAAAGAAGGTGGATTGCAACATTATTATACGGTGTTTGGTCAAATCAAGGGGAAGCTTGT
TATTGGTGATCCAGATCCTAGCAAGAAGGTCATTAAAATGCCCTTAGAGGAGTTTGCCAAAGAGTGGACGGGAGTTGCTC
TCTTTTTTGTTCCAGGAGAAACTTACACTAAATACAAAGAAGATGTGCCTGGGCTTCTTTCATTTTTACCAATTTTGTTT
CGTCGTAAGGGTTTGATTGCAGTTATTGTCTTGTTAAGTTTTCTAGTGACCCTTGTTAATATTATTGGTTCTTATTATTT
GCAATCTATTATTGACCGCTTGATTCCTCAGGAGGCCTACACTCTTCTAACCATGATTTCGCTAGGCCTATGTATCTCTT
ATCTAGCTCAACAAGTATTTACTTTTTTCAAAGATTATCTTCTACATCGATTGGGGAATTACTTGTCCATTGCTGTCATT
CTTCCTTATATTAAGCATGTCCTTTCCTTACCTATTAGTTTCTTTAGTTCACGTCGTACTGGTGAAATAACGTCACGTTT
TGGCGATGCTAACACTATTATCGATGCTCTAGCTTCAACGATTTTATCGATTTTCCTAGATGTGACCATTGTGATGACTC
TAGCTGTGGCTCTTATTTTACAAAATCAGTCACTTTTTGTGATGACTCTCACGGTAGTGCCTCTTTATGTTTTAATCATT
TTGGCCTTCTATAAGCTTTTTGAAAAGGAAAATTATCAATTGATGGAGGCAAATAGTCAGGTCAATACCGCTGTTATTGA
TGATTTGCGAGGCATTGAAACCTTAAAATCCTTGAGAGTTGAAGAAAGACGCTATCAGGAAATTGAGGTGAAATTCCATG
ACTATTTGAAGAAGTCTTTGTCTAAGGCCAAGTGGCAATTAACACAGGATGGTTTAAAGACAGGGGTTCAGTTAGTTTCC
AATGTCTTTATCCTATGGTATGGGGCACAATTGGTCATGGAAGGACAGCTATCTGCAGGTCAGTTGATTACCTATAATAT
GTTGCTGAATTATTTTACAACTCCTTTAATTAATATTATCAATCTCCAATCTAAAATTCAGCAAGCCAAAGTAGCCAATA
ATCGTCTTCAAGAAGTTTATGTTGTGGATAAGGAAGAAAAAGGAAAACTTAAAGAGTTATCCTTTAAACAACTTGCTCTT
AAGGGTGTTAGTCACCGTTTTAGTTATCAGCAAGAGACGCTTAGTAAGATTGATTTAACGATTCATAAGGGGGAGAAAAT
CGCCCTCATGGGTAAAAGTGGATCTGGGAAAACGACCTTGGCTAAAATGTTGTCGGGTTATTACACAAAATCTAGTGGTC
ATGTAACCCTAGATAAAGATGCTATTAGCCATGCGGAGCTGCGTCAAATGGTGACTTACGTTCCCCAGCAGACCTATGTG
TTTACAGGCACTATTTTAGAAAATCTGCTATTAGGATTTGAAGGAGAAGTTGACGAGAAAAAGCTTCTTAAAGTTTGCCA
ACAAGCTGATATCTTAGAGGATATTCAAAAAATGCCACTAGGTTTTCAGACCCAAGTATCTGAAGATGGTGGTCTATCTG
GTGGTCAAAAACAACGCTTGGCGATAGCGAGAGCCCTCTTGTCCCAGCAGCCTATCTTGATTTTTGACGAAGCTACCAGT
GGTCTCGATAGTGATACTGAAAGCAGGGTCATGGCTAATCTTGCTAAGATTAAACGAACAATGATTTTTATTGCTCACCG
CAATAGTGTTCGTCAACATGTCGGTCGTGTGGTGACCATGGTGAGTGGCCAGATTGAGTCGGACAGTCCTAATTTCAATC
CATTCCAGTTTATTTAA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(3-139)

ABC transporter (ABC_tran)

(494-640)

ABC transporter transmembrane region (ABC_membrane)

(167-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis SK321

54.124

98.997

0.536
  comA Streptococcus gordonii str. Challis substr. CH1

53.448

99.713

0.533
  comA Streptococcus mitis NCTC 12261

53.69

98.997

0.532
  comA Streptococcus pneumoniae Rx1

53.546

98.997

0.53
  comA Streptococcus pneumoniae D39

53.546

98.997

0.53
  comA Streptococcus pneumoniae R6

53.546

98.997

0.53
  comA Streptococcus pneumoniae TIGR4

53.401

98.997

0.529
  comA/nlmT Streptococcus mutans UA159

50.29

98.854

0.497

Multiple sequence alignment