Detailed information NTG1138625

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: DQM58_RS08375
• Genome accession: NZ_LS483363
• Coordinates: 1649879..1650589 (-)
• Length: 236 a.a.
• NCBI ID: WP_012766682.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC9414
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1644879..1655589

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM58_RS08355 (NCTC9414_01710)	rnc	1645303..1645995 (-)	693	WP_003057240.1	ribonuclease III	-
DQM58_RS08360 (NCTC9414_01711)	-	1646270..1647133 (+)	864	WP_003060834.1	IS982 family transposase	-
DQM58_RS08365 (NCTC9414_01712)	vicX	1647721..1648530 (-)	810	WP_003059746.1	MBL fold metallo-hydrolase	Regulator
DQM58_RS08370 (NCTC9414_01713)	vicK	1648534..1649886 (-)	1353	WP_022554366.1	cell wall metabolism sensor histidine kinase VicK	Regulator
DQM58_RS08375 (NCTC9414_01714)	vicR	1649879..1650589 (-)	711	WP_012766682.1	response regulator YycF	Regulator
DQM58_RS08380 (NCTC9414_01715)	-	1650854..1651621 (+)	768	WP_111681600.1	amino acid ABC transporter ATP-binding protein	-
DQM58_RS08385 (NCTC9414_01716)	-	1651648..1652448 (+)	801	WP_003057243.1	transporter substrate-binding domain-containing protein	-
DQM58_RS08390 (NCTC9414_01717)	-	1652462..1653163 (+)	702	WP_046159505.1	amino acid ABC transporter permease	-
DQM58_RS08395 (NCTC9414_01718)	-	1653178..1653825 (+)	648	WP_111681599.1	amino acid ABC transporter permease	-
DQM58_RS08400 (NCTC9414_01719)	-	1653921..1654916 (-)	996	WP_003057220.1	DUF3114 domain-containing protein	-

Sequence

Protein

• Length: 236 a.a.
• Molecular weight: 27057.95 Da
• Isoelectric Point: 5.0023

>NTDB_id=1138625 DQM58_RS08375 WP_012766682.1 1649879..1650589(-) (vicR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC9414]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFVAKKHGKEVE
LTHREFELLHHLANHMGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide

• Length: 711 bp

>NTDB_id=1138625 DQM58_RS08375 WP_012766682.1 1649879..1650589(-) (vicR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC9414]
ATGAAAAAAATACTGATTGTGGATGATGAAAAACCGATTTCTGACATTATTAAGTTTAATTTGACAAAAGAAGGTTATGA
CATTGTTACAGCTTTTGATGGACGCGAAGCGGTAACAATTTTTGAAGAAGAAAAGCCAGATTTAATTATTCTTGATTTGA
TGCTCCCTGAGTTGGACGGTCTTGAAGTAGCCAAGGAAATTCGTAAAACCAGTCATGTCCCGATTATTATGCTGTCGGCT
AAGGATAGTGAGTTTGACAAGGTCATTGGTCTTGAAATTGGGGCAGATGATTATGTTACCAAACCTTTTTCAAATCGTGA
ACTATTAGCTCGTGTCAAGGCTCATTTACGTCGAACAGAAACGATCGAAACAGCCGTAGCAGAGGAAAATGCTTCTTCAG
GTTCACAAGAGTTAACCATTGGTAATTTACAAATTTTACCAGATGCTTTTGTGGCTAAAAAACATGGCAAAGAAGTGGAA
TTAACCCATCGTGAATTTGAATTATTACACCACCTGGCCAATCATATGGGTCAAGTGATGACACGAGAGCACTTGCTTGA
GACGGTTTGGGGCTATGATTACTTTGGCGATGTCCGTACTGTTGACGTGACGGTTCGTCGTCTGCGTGAAAAAATTGAAG
ACACACCAAGCCGTCCCGAATATATTTTAACGAGACGCGGTGTTGGGTACTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (156-231)

• Response regulator receiver domain (Response_reg) (4-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	90.678	100	0.907
micA	Streptococcus pneumoniae Cp1015	79.487	99.153	0.788
covR	Lactococcus lactis subsp. lactis strain DGCC12653	44.828	98.305	0.441
covR	Streptococcus salivarius strain HSISS4	44.828	98.305	0.441
scnR	Streptococcus mutans UA159	37.712	100	0.377