Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   DQM58_RS08370 Genome accession   NZ_LS483363
Coordinates   1648534..1649886 (-) Length   450 a.a.
NCBI ID   WP_022554366.1    Uniprot ID   A0A9X8T4M5
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC9414     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1643534..1654886
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM58_RS08355 (NCTC9414_01710) rnc 1645303..1645995 (-) 693 WP_003057240.1 ribonuclease III -
  DQM58_RS08360 (NCTC9414_01711) - 1646270..1647133 (+) 864 WP_003060834.1 IS982 family transposase -
  DQM58_RS08365 (NCTC9414_01712) vicX 1647721..1648530 (-) 810 WP_003059746.1 MBL fold metallo-hydrolase Regulator
  DQM58_RS08370 (NCTC9414_01713) vicK 1648534..1649886 (-) 1353 WP_022554366.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQM58_RS08375 (NCTC9414_01714) vicR 1649879..1650589 (-) 711 WP_012766682.1 response regulator YycF Regulator
  DQM58_RS08380 (NCTC9414_01715) - 1650854..1651621 (+) 768 WP_111681600.1 amino acid ABC transporter ATP-binding protein -
  DQM58_RS08385 (NCTC9414_01716) - 1651648..1652448 (+) 801 WP_003057243.1 transporter substrate-binding domain-containing protein -
  DQM58_RS08390 (NCTC9414_01717) - 1652462..1653163 (+) 702 WP_046159505.1 amino acid ABC transporter permease -
  DQM58_RS08395 (NCTC9414_01718) - 1653178..1653825 (+) 648 WP_111681599.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51476.06 Da        Isoelectric Point: 5.7411

>NTDB_id=1138624 DQM58_RS08370 WP_022554366.1 1648534..1649886(-) (vicK) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC9414]
MTRDIIGNLSAFELAILLLLVFVAFYFIHLAVRDYRNARIIRMMSHKIRDLINGRYTDMINEKADIELMELADQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLTKEKALEKNITDLLEGDTPYTYRELVSKTPV
VTVNSRNDMGEFVTLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLSVEMTNFTAFMTSILNRFDLVKNQHTGTGKVYEIVRDYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEDDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=1138624 DQM58_RS08370 WP_022554366.1 1648534..1649886(-) (vicK) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC9414]
ATGACTAGAGATATCATTGGAAACTTATCTGCTTTTGAATTAGCGATTCTCTTATTACTTGTTTTTGTTGCCTTTTATTT
TATTCACTTAGCGGTGCGTGATTACCGAAATGCCCGTATTATTCGAATGATGAGCCATAAAATCAGAGACCTGATTAATG
GCCGTTATACCGACATGATTAACGAAAAGGCTGACATTGAATTGATGGAACTGGCAGATCAGTTAAACGATCTCTCAGAC
GTGTTTCGCTTAACCCATGAGAATCTTGCTCAGGAAAAAAATCGCTTGGCCAGCATTCTGGCCTATATGTCAGATGGCGT
ACTTGCCACAGACCGTTCTGGGAAAATCATCATGATTAACGAGACTGCCCGCAAGCAGCTCAATCTGACCAAGGAGAAGG
CCCTTGAAAAGAACATTACCGATTTGTTGGAGGGAGATACCCCCTATACCTATCGTGAATTGGTTTCCAAAACGCCTGTT
GTGACGGTCAATAGTCGCAATGACATGGGTGAGTTTGTGACATTACGTTTACGCTTCGCCTTAAACAGACGAGAAAGTGG
TTTTATTTCTGGTTTGGTTGTGGTGCTCCATGACACTACAGAACAGGAAAAGGAAGAACGTGAACGCCGGTTGTTTGTTT
CTAATGTGAGTCATGAGTTGAGAACACCTTTGACATCGGTGAAATCCTACTTGGAAGCTCTTGATGAAGGTGCACTTAAA
GAAGATATTGCTCCAAGTTTCATAAAAGTTTCTCTTGATGAAACTAATCGGATGATGCGTATGATTTCTGATCTTTTAAA
CTTGTCTCGCATTGATAACCAAGTAACTCAGTTATCTGTCGAGATGACCAATTTTACAGCTTTTATGACATCTATCCTGA
ACCGATTTGACCTAGTTAAAAACCAGCACACCGGTACTGGCAAGGTTTATGAAATTGTGAGAGACTATCCGATTACCTCT
GTTTGGCTGGAAATTGATAATGATAAGATGACGCAGGTTATTGAAAATATCCTAAACAACGCGATTAAATACTCTCCTGA
TGGTGGGAAAATCACTGTTCGCATGAAAACAACCGACACGCAATTGATTATTTCCATCTCAGACCAAGGCTTAGGCATTC
CGAAGAAGGATCTGCCCCTTATTTTTGACCGTTTTTACCGTGTGGACAAGGCAAGAAGCCGTGCTCAAGGTGGAACTGGT
CTAGGGCTTGCCATTGCCAAAGAAATTATTAAGCAGCATCACGGGTTTATTTGGGCGAAGAGTGATTATGGCAAAGGATC
AACCTTTACCATCGTCTTGCCATATGAAAAAGATGCTGCCATTTACGAAGAGTGGGAGGATGACATAGATTAA

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-165)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.43

92

0.676
  micB Streptococcus pneumoniae Cp1015

66.824

94.444

0.631

Multiple sequence alignment