Detailed information NTG1138582

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: DQM58_RS00350
• Genome accession: NZ_LS483363
• Coordinates: 55574..56485 (+)
• Length: 303 a.a.
• NCBI ID: WP_003060893.1
• Uniprot ID: A0AAE9U6L1
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC9414
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 50574..61485

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM58_RS00325 (NCTC9414_00066)	purE	51075..51563 (+)	489	WP_003062588.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
DQM58_RS00330 (NCTC9414_00067)	purK	51550..52623 (+)	1074	WP_111681477.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
DQM58_RS00335 (NCTC9414_00068)	-	52633..53889 (+)	1257	WP_012766419.1	DUF4041 domain-containing protein	-
DQM58_RS00340 (NCTC9414_00069)	-	53882..54091 (+)	210	WP_014611912.1	hypothetical protein	-
DQM58_RS00345 (NCTC9414_00070)	purB	54140..55432 (+)	1293	WP_003056595.1	adenylosuccinate lyase	-
DQM58_RS00350 (NCTC9414_00071)	comR	55574..56485 (+)	912	WP_003060893.1	XRE family transcriptional regulator	Regulator
DQM58_RS11135 (NCTC9414_00072)	comS	56572..56670 (+)	99	WP_198763767.1	quorum-sensing system DWW-type pheromone	Regulator
DQM58_RS00355 (NCTC9414_00073)	ruvB	56704..57702 (+)	999	WP_015057190.1	Holliday junction branch migration DNA helicase RuvB	-
DQM58_RS00360 (NCTC9414_00074)	-	57837..58268 (+)	432	WP_003059365.1	low molecular weight protein-tyrosine-phosphatase	-
DQM58_RS00365 (NCTC9414_00075)	-	58297..58698 (+)	402	WP_003049089.1	MORN repeat-containing protein	-
DQM58_RS00370 (NCTC9414_00076)	-	58695..60470 (+)	1776	WP_003059359.1	acyltransferase family protein	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35995.62 Da
• Isoelectric Point: 4.7392

>NTDB_id=1138582 DQM58_RS00350 WP_003060893.1 55574..56485(+) (comR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC9414]
MLEHFGEKVRGLRLEKGISREELCGDEAELSVRQLARIELGQSIPSLAKVIFIAKALEVSVGYLTDGANLELPKRYKELK
YLILRTPTYMDDRKLQVRESQFDEIFENYYDQLPEEEKIAIDIIQAKFEVYQTGDINFGFNILKEFLPQLKKKTVYNLNE
LLLIDLYLIILVVSNFTNDLFDEEFYKEITERILEQHQYLLLEDLFLLNNILLSCADTSIRLKMFERLKDTLQLSHFIMS
TIQDFQRMPMYCMYEWKLSIFYLKDIKRAETYFSQSLTFTQMTNDSYLAQKLQKEWDKDIHPS

Nucleotide

• Length: 912 bp

>NTDB_id=1138582 DQM58_RS00350 WP_003060893.1 55574..56485(+) (comR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC9414]
ATGTTAGAGCATTTTGGTGAAAAAGTGAGAGGATTAAGACTTGAGAAAGGGATTAGTCGAGAGGAATTGTGTGGAGATGA
GGCAGAATTGTCTGTTCGCCAGTTGGCGAGGATAGAGCTAGGTCAATCTATACCAAGTTTAGCGAAGGTTATTTTTATTG
CGAAAGCCTTAGAGGTCAGCGTCGGTTATTTGACGGATGGCGCTAACCTAGAACTCCCTAAACGATATAAAGAGTTAAAA
TATCTTATTTTAAGGACTCCGACTTATATGGACGATCGCAAATTACAGGTCCGGGAGTCTCAGTTTGATGAGATATTTGA
AAACTATTATGATCAATTGCCTGAGGAAGAAAAAATAGCGATTGATATTATCCAGGCAAAATTTGAAGTTTATCAGACAG
GTGATATTAATTTTGGTTTTAATATTTTAAAAGAATTTCTACCACAACTAAAAAAGAAAACGGTTTATAACTTAAATGAA
TTATTATTAATTGATTTATATTTAATTATTTTAGTTGTTTCTAACTTTACAAATGACCTATTTGATGAGGAATTTTATAA
AGAAATAACGGAGCGAATCTTAGAACAGCATCAATACCTGTTATTAGAAGATTTATTTCTATTAAATAATATTCTTTTAT
CTTGCGCAGATACTTCTATTCGTTTAAAAATGTTTGAACGACTAAAGGATACGTTACAACTCAGCCATTTTATTATGTCA
ACCATTCAAGATTTTCAGCGAATGCCCATGTATTGCATGTATGAATGGAAATTGTCTATCTTTTATTTAAAAGATATTAA
ACGAGCAGAAACTTATTTTAGTCAATCTCTCACGTTTACTCAAATGACTAATGATAGTTATTTGGCACAAAAGCTTCAAA
AAGAATGGGATAAGGATATTCATCCCTCTTAA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (12-64)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS315	83.389	99.34	0.828
comR	Streptococcus pyogenes MGAS8232	55.629	99.67	0.554
comR	Streptococcus mutans UA159	46.154	98.68	0.455
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	46.575	96.37	0.449
comR	Streptococcus suis P1/7	37.288	97.36	0.363
comR	Streptococcus suis 05ZYH33	37.288	97.36	0.363