Detailed information NTG1138471

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQM47_RS04650
• Genome accession: NZ_LS483360
• Coordinates: 910541..911377 (-)
• Length: 278 a.a.
• NCBI ID: WP_023079425.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC10876
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 905541..916377

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM47_RS04625 (NCTC10876_00922)	-	905772..906764 (-)	993	WP_023610823.1	D-lactate dehydrogenase	-
DQM47_RS04630 (NCTC10876_00923)	-	906779..907332 (-)	554	Protein_841	PTS sugar transporter subunit IIC	-
DQM47_RS09880	-	907345..908229 (+)	885	Protein_842	LysR family transcriptional regulator	-
DQM47_RS04645 (NCTC10876_00925)	topA	908304..910433 (-)	2130	WP_063632951.1	type I DNA topoisomerase	-
DQM47_RS04650 (NCTC10876_00926)	dprA	910541..911377 (-)	837	WP_023079425.1	DNA-processing protein DprA	Machinery gene
DQM47_RS04655 (NCTC10876_00927)	-	911442..912233 (-)	792	WP_023610685.1	ribonuclease HII	-
DQM47_RS04660 (NCTC10876_00928)	ylqF	912223..913071 (-)	849	WP_023610651.1	ribosome biogenesis GTPase YlqF	-
DQM47_RS04665 (NCTC10876_00929)	-	913290..913730 (+)	441	WP_002989774.1	DUF1836 domain-containing protein	-
DQM47_RS04670 (NCTC10876_00930)	trhA	913727..914377 (+)	651	WP_023079408.1	PAQR family membrane homeostasis protein TrhA	-
DQM47_RS04675 (NCTC10876_00931)	-	914494..915405 (+)	912	WP_023079407.1	diacylglycerol/lipid kinase family protein	-
DQM47_RS04680 (NCTC10876_00932)	-	915455..915889 (-)	435	WP_023079442.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31046.98 Da
• Isoelectric Point: 8.5827

>NTDB_id=1138471 DQM47_RS04650 WP_023079425.1 910541..911377(-) (dprA) [Streptococcus pyogenes strain NCTC10876]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEDR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1138471 DQM47_RS04650 WP_023079425.1 910541..911377(-) (dprA) [Streptococcus pyogenes strain NCTC10876]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCTGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTCAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACTGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGACCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367