Detailed information NTG1138416

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQL29_RS04610
• Genome accession: NZ_LS483359
• Coordinates: 892296..893132 (+)
• Length: 278 a.a.
• NCBI ID: WP_002989770.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC12068
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 887296..898132

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL29_RS04580 (NCTC12068_00903)	-	887847..888218 (+)	372	WP_014407581.1	hypothetical protein	-
DQL29_RS04585 (NCTC12068_00904)	-	888268..889179 (-)	912	WP_002989777.1	diacylglycerol/lipid kinase family protein	-
DQL29_RS04590 (NCTC12068_00905)	trhA	889296..889946 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DQL29_RS04595 (NCTC12068_00906)	-	889943..890383 (-)	441	WP_011017769.1	DUF1836 domain-containing protein	-
DQL29_RS04600 (NCTC12068_00907)	ylqF	890602..891450 (+)	849	WP_030125932.1	ribosome biogenesis GTPase YlqF	-
DQL29_RS04605 (NCTC12068_00908)	-	891440..892231 (+)	792	WP_030125931.1	ribonuclease HII	-
DQL29_RS04610 (NCTC12068_00909)	dprA	892296..893132 (+)	837	WP_002989770.1	DNA-processing protein DprA	Machinery gene
DQL29_RS04615 (NCTC12068_00910)	topA	893239..895368 (+)	2130	WP_030125930.1	type I DNA topoisomerase	-
DQL29_RS08790	-	895443..896300 (-)	858	Protein_837	LysR family transcriptional regulator	-
DQL29_RS04630 (NCTC12068_00912)	-	896340..896906 (+)	567	Protein_838	PTS sugar transporter subunit IIC	-
DQL29_RS04635 (NCTC12068_00913)	-	896921..897913 (+)	993	WP_002989762.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30956.84 Da
• Isoelectric Point: 8.5841

>NTDB_id=1138416 DQL29_RS04610 WP_002989770.1 892296..893132(+) (dprA) [Streptococcus pyogenes strain NCTC12068]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1138416 DQL29_RS04610 WP_002989770.1 892296..893132(+) (dprA) [Streptococcus pyogenes strain NCTC12068]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATAGAATTTAAACAGTTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367