Detailed information NTG1138132

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: DQL13_RS00280
• Genome accession: NZ_LS483354
• Coordinates: 47707..48621 (+)
• Length: 304 a.a.
• NCBI ID: WP_012514714.1
• Uniprot ID: A0AAW3GQI0
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC11606
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 42707..53621

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL13_RS00260 (NCTC11606_00052)	purE	43871..44359 (+)	489	WP_012514711.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
DQL13_RS00265 (NCTC11606_00053)	purK	44346..45437 (+)	1092	WP_012514712.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
DQL13_RS00270 (NCTC11606_00054)	-	45447..45671 (+)	225	WP_012514713.1	hypothetical protein	-
DQL13_RS10090	-	45695..45799 (+)	105	WP_370444775.1	hypothetical protein	-
DQL13_RS00275 (NCTC11606_00055)	purB	46116..47408 (+)	1293	WP_037583922.1	adenylosuccinate lyase	-
DQL13_RS00280 (NCTC11606_00056)	comR	47707..48621 (+)	915	WP_012514714.1	helix-turn-helix domain-containing protein	Regulator
DQL13_RS10110 (NCTC11606_00057)	comS	48704..48802 (+)	99	WP_021320241.1	quorum-sensing system DWW-type pheromone	Regulator
DQL13_RS00285 (NCTC11606_00058)	ruvB	48836..49837 (+)	1002	WP_012514715.1	Holliday junction branch migration DNA helicase RuvB	-
DQL13_RS00290 (NCTC11606_00059)	-	50123..50581 (+)	459	WP_012514717.1	low molecular weight protein-tyrosine-phosphatase	-
DQL13_RS00295 (NCTC11606_00060)	-	50587..50988 (+)	402	WP_012514718.1	MORN repeat-containing protein	-
DQL13_RS00300 (NCTC11606_00061)	-	50985..52766 (+)	1782	WP_111721605.1	acyltransferase family protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35823.41 Da
• Isoelectric Point: 4.5517

>NTDB_id=1138132 DQL13_RS00280 WP_012514714.1 47707..48621(+) (comR) [Streptococcus equi subsp. zooepidemicus strain NCTC11606]
MLDNFGEKVRDLRYQKKITREDLCGDESELSIRQLARIELGQSIPSLSKVVYIAKALDVSVGFLTDGEDLELPKRYKELK
YLILRTPTYMDDDKLKLREEQFDEIFEDYYDQLPEEEKLVVDCLQSIMDTLLTENINFGVGLLQEYFEQTKSKTQFREND
LILIELYLAYLDIVGMNGEYSDKGFYDSLLDILLNQFEHFELEELFIVNKIAIGISSLSIKSNKLEILEKVIVLSQKIIL
KTQDFNRMPILNLIEWKYALMKKKDIEMAKKCYDKACLFAQLTGDQYLEKKLREEWGKDIKRYQ

Nucleotide

• Length: 915 bp

>NTDB_id=1138132 DQL13_RS00280 WP_012514714.1 47707..48621(+) (comR) [Streptococcus equi subsp. zooepidemicus strain NCTC11606]
ATGTTAGACAATTTTGGTGAAAAGGTGAGAGACCTTCGGTATCAGAAAAAAATTACCAGAGAGGATTTATGTGGAGATGA
GTCAGAATTATCCATTCGTCAATTGGCACGAATAGAACTGGGCCAATCGATTCCCAGCCTATCAAAGGTGGTTTATATTG
CTAAGGCTCTGGACGTTAGTGTCGGCTTTTTGACAGACGGAGAGGATTTGGAGCTGCCTAAGCGTTATAAAGAACTTAAA
TATTTGATTTTAAGAACGCCGACCTATATGGATGATGACAAATTAAAGCTGCGAGAAGAGCAATTTGACGAAATTTTTGA
AGATTATTATGACCAGTTGCCAGAGGAAGAAAAGCTTGTGGTGGACTGCTTGCAGTCCATAATGGATACGTTATTAACCG
AGAATATCAATTTTGGAGTTGGGTTATTACAGGAATACTTTGAACAGACAAAAAGCAAGACTCAATTTAGAGAGAATGAC
CTTATTCTTATTGAGCTGTATTTAGCGTATCTGGATATTGTGGGAATGAATGGAGAGTATTCAGATAAAGGATTCTATGA
TTCTTTATTAGACATTTTGTTAAATCAGTTTGAACATTTTGAATTAGAGGAATTATTTATCGTCAATAAAATAGCTATAG
GGATTTCCTCGTTGAGCATCAAAAGCAATAAGCTGGAGATTCTTGAGAAGGTTATTGTGCTTAGTCAAAAAATTATTCTC
AAGACTCAGGATTTCAATAGAATGCCTATCTTAAATTTGATAGAGTGGAAATACGCTTTAATGAAGAAAAAAGACATAGA
AATGGCCAAAAAATGCTATGATAAGGCATGCCTGTTTGCTCAATTAACAGGAGATCAGTATTTGGAAAAGAAATTGAGAG
AAGAATGGGGTAAAGATATAAAACGATATCAATAG

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-296)

• Helix-turn-helix (HTH_3) (10-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	74.257	99.671	0.74
comR	Streptococcus pyogenes MGAS315	54.485	99.013	0.539
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	51.379	95.395	0.49
comR	Streptococcus mutans UA159	49.498	98.355	0.487
comR	Streptococcus suis P1/7	38.591	98.026	0.378
comR	Streptococcus suis 05ZYH33	38.644	97.039	0.375
comR	Streptococcus suis D9	37.037	97.697	0.362