Detailed information NTG1137993

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQM42_RS05260
• Genome accession: NZ_LS483351
• Coordinates: 962899..963735 (+)
• Length: 278 a.a.
• NCBI ID: WP_002984620.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC8195
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 957899..968735

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM42_RS05230 (NCTC8195_01050)	-	958381..958821 (+)	441	WP_002984633.1	hypothetical protein	-
DQM42_RS05235 (NCTC8195_01051)	-	958871..959782 (-)	912	WP_002984631.1	diacylglycerol/lipid kinase family protein	-
DQM42_RS05240 (NCTC8195_01052)	trhA	959899..960549 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DQM42_RS05245 (NCTC8195_01053)	-	960546..960986 (-)	441	WP_002984627.1	DUF1836 domain-containing protein	-
DQM42_RS05250 (NCTC8195_01054)	ylqF	961205..962053 (+)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
DQM42_RS05255 (NCTC8195_01055)	-	962043..962834 (+)	792	WP_002984622.1	ribonuclease HII	-
DQM42_RS05260 (NCTC8195_01056)	dprA	962899..963735 (+)	837	WP_002984620.1	DNA-processing protein DprA	Machinery gene
DQM42_RS05265 (NCTC8195_01057)	topA	963842..965971 (+)	2130	WP_002984618.1	type I DNA topoisomerase	-
DQM42_RS05270 (NCTC8195_01058)	trmFO	966106..967452 (+)	1347	WP_011888869.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30984.94 Da
• Isoelectric Point: 8.8230

>NTDB_id=1137993 DQM42_RS05260 WP_002984620.1 962899..963735(+) (dprA) [Streptococcus pyogenes strain NCTC8195]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCITSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1137993 DQM42_RS05260 WP_002984620.1 962899..963735(+) (dprA) [Streptococcus pyogenes strain NCTC8195]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTTCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGTCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CATCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.986	100	0.68
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363